... Ishikawa T, Nakagawa S, Yamaguchi T,Yoshida N, Minami M, Kita M, Imanishi J, Yoshikawa T: Enhancedintestinal inflammation induced by dextran sulfate sodium in tumor necrosis factor-alpha deficient ... of edema, acute inflammatory infiltrates, and focal ulceration. Chronic colitis generated by 3 cycles of 5 days of 3% DSS in drinking water, followed by 16 days of plain water resulted in development ... began (day 0), at the end of each 5 day cycle of DSSadministration (day 5, 26, and 47, and after 16 days of recovery prior to beginning the next DSS cycle (days 21,42, and 63). Freshly obtained...