Báo cáo khoa học: "Modification of pharmacokinetics of norfloxacin following oral administration of curcumin in rabbits" pps

Báo cáo khoa học: "Medical treatment for the terminally ill: the ‘risk of unacceptable badness’"

... end -of- life issues to patients and their families[11]. It is not uncommon for physicians to ask loadedquestions in their quest for end -of- life decisions. For example, ‘This is your grandmother’s ... futile. Under the current rules, the only test of futility is that embodied by the question, ‘Will this treatment result in sustained life?’ If the answer is ‘yes’,then virtually any treatment is ... revitalize the patient.Perhaps the most effective way of dealing with strong familialincentives to tread the path of least resistance in end -of- lifecare is twofold. First, in end -of- life issue...

Tài liệu Báo cáo khoa học: The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid ppt

... antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid Bilal A. Azakir, Guillaume Desrochers and Annie AngersDe´partement ... tBid levels and the ubiquitin ligase activity of Itch. In this study, we first examined the ability of Itch tointeract with Bid and tBid. We found that Itch specifi-cally interacts with tBid, but ... proteins Bim and Bak and the C-terminal fragment of Bid. The ubiquitin ligases responsible for the ubiquitylation are in most cases not known [44].Here, we have identified Itch as the ubiquitin ligase responsible...

Tài liệu Báo cáo khoa học: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle doc

... Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle Nikolai P. Kaimachnikov1,2 and Boris N. Kholodenko1,31 Department of Pathology, ... branch of the Z-shaped curve (i.e. low Src activity) and the stateO3at the upper branch (i.e. high Src activity) are both Switches, pulses and oscillations in Src signaling N. P. Kaimachnikov and ... activators and inhibitors, and the Src abundanceaffect the basal low activity state of Src and bringabout oscillations, pulses and toggle switches in Src activity.Figure 5 shows regions in the plane...

Tài liệu Báo cáo khoa học: Competition between innate multidrug resistance and intracellular binding of rhodamine dyes pdf

... 2008 FEBS Competition between innate multidrug resistance and intracellular binding of rhodamine dyes Daniella Yeheskely-Hayon, Ronit Regev, Hagar Katzir and Gera D. EytanDepartment of Biology, ... activepumping of the agents out of the cells and their pas-sive uptake [10,31] and (b) competition between theactive pumping of the agents out of the cells and their intracellular binding to receptors and ... the multidrug resistance- associated protein (MRP1, ABCC1) [6] and breast cancer resistance protein (BCRP⁄ MXR ⁄ ABCP,Keywords innate multidrug resistance; MDR; MRP1; multidrug resistance; rhodaminesCorrespondenceG....

Tài liệu Báo cáo khoa học: A facile method for expression and puriﬁcation of the Alzheimer’s disease-associated amyloid b-peptide pdf

... GGGTTCT AACAAGGGTGCT-3Â;Abc, 5Â-CACAACGCCACCAACCATCAGACCGATGATAGCACCCTTGTTAGAACCCAC-3Â;Ab-start, 5Â-GCGTAGGGTCGACATATGGACGCTGAATTCCGTCACG-3Â;Abstop, 5Â-CCTGCCGAGCTCCTATTACACAACGCCACCAACCATCAG-3Â. The ... according to the manufacturer’s guidelines and using the following primers: Aba, 5Â-ATGGACGCTGAATTCCGTCACGACTCTGGTTACGAAGTTCACCACCAGAAGCTGGTG-3Â;Abb, 5Â-GTTCACCACCAGAAGCTGGTGTTCTTC GCTGAA GACGT GGGTTCT ... SEC-isolated Ab(1–40) and Ab(M1–40) are at least 97%pure. In the lanes containing Ab(1–42) and Ab(M1–42), there were prominent bands at approximately4 kDa and faint bands at approximately 14 kDa....

Báo cáo khoa học: A novel splicing variant form suppresses the activity of full-length signal transducer and activator of transcription 5A pot

... thataggregation of STAT 5A_ DE18 suppresses the tran-scriptional activity of STAT 5A. DiscussionWe isolated a novel STAT 5A splicing variant from the mouse brainstem. The STAT 5A_ DE18 variant lacked the transactivation ... activity of full-length signal transducer and activator of transcription 5A Yoshihisa Watanabe1, Masaya Ikegawa2, Yoshihisa Naruse3 and Masaki Tanaka11 Department of Cell Biology, Research ... with Flag–STA-T 5A_ FL and STAT 5A_ DE18–EGFP (B–D) or Flag–STAT 5A_ FL alone (E–G). Flag–STAT 5A_ FL was detected with a primary antibody againstSTAT 5A_ FL and Alexa Fluor 546-conjugated secondary antibody...

Báo cáo khoa học: "Modification of pharmacokinetics of cefotaxime in uranyl nitrate-induced renal damage in black bengal goats" pps

... 6FLHQFHJ. Vet. Sci. (2004),/5(1), 1–3Modification of pharmacokinetics of cefotaxime in uranyl nitrate-induced renal damage in black bengal goatsBiswa Priya Dutta, Shiben Chandra Debnath, ... available in kidney damaged goats. Therefore, thepresent study, investigates the alteration of dispositionkinetics of cefotaxime in healthy and kidney damaged goatsfollowing single intramuscular ... concentration of cefotaxime at differenttime interval after single dose intramuscular administrationat 50 mg/kg in healthy goats has been incorporated in Fig. 1. Cefotaxime could be detected in plasma of...

Báo cáo khoa học: " Modification of maturation condition improves oocyte maturation and in vitro development of somatic cell nuclear transfer pig embryos" pps

... class="bi x0 y3 w3 h 5" alt ="" ...

Báo cáo khoa học: "Modification of pharmacokinetics of norfloxacin following oral administration of curcumin in rabbits" pps

... Modification of pharmacokinetics of norfloxacin following oral administration of curcumin in rabbits 295Fig. 1. Semilogarithmic plot of plasma concentration-time profile of norfloxacin in control ... examine the influence of curcumin on the disposition profile of norfloxacin in rabbits after oral administration. The disposition of norfloxacin after a single oral dose JOURNAL OF VeterinaryScienceJ. ... disposition of norfloxacin following single oral administration. Sixteen rabbits were divided into two groups of eight each consisting of either sex. Animals in group-I were administered norfloxacin...

báo cáo khoa học: " Patient- and delivery-level factors related to acceptance of HIV counseling and testing services among tuberculosis patients in South Africa: a qualitative study with " pdf

... delivery-level factors related to acceptance of HIV counseling and testing services among tuberculosis patients in South Africa: a qualitative study with community healthworkers and program managersJ ... program managers also pointed to a lack of appropriately trained staff members, as well as p oorinfrastructure to monitor and deliver HCT, as factors contributing to low acceptance rates among ... Ouedraogo H, Matteelli A, Sawadogo M:Access to and uptake of HIV testing among TB patients in Burkina Faso.38th World Conference on Lung Health of the International Union Against Tuberculosis and...

báo cáo khoa học: " Modification of a neuronal network direction using stepwise photo-thermal etching of an agarose architecture" pptx

... citation purposes)Journal of NanobiotechnologyOpen AccessResearch Modification of a neuronal network direction using stepwise photo-thermal etching of an agarose architectureIkurou Suzuki1, ... micro-chambers in a step-by-step fashion. This has helped us tounderstand the meaning of the spatial pattern of a neuro-nal network by comparing the changes in cell signalingbefore and after changing ... cultivation and observation, image analysis.They were equally contributed for this article. KY con-ceived of the study, and participated in its design andcoordination. All authors read and approved...

báo cáo khoa học: "Sub-cellular internalization and organ specific oral delivery of PABA nanoparticles by side chain variation" pdf

... and organ specific oral delivery of PABA nanoparticles by side chain variation.Journal of Nanobiotechnology 2011 9:10.Submit your next manuscript to BioMed Central and take full advantage of: ... entry into the food chain via eco-consumers.Efficiency of organ specific delivery of PABA nanomaterials by side chain variation in DrosophilaTo categorize the intensity of fluorescent molecules ... erties of PABA nanopart icles and their uptake mechanism that facilitates targeted organ delivery via oral consumption.ResultsSynthesis of nanoparticles Nanoparticles with different side chain...

báo cáo khoa học: " Mapping QTLs for oil traits and eQTLs for oleosin genes in jatropha" ppsx

... Access Mapping QTLs for oil traits and eQTLs for oleosin genes in jatrophaPeng Liu, Chun Ming Wang*, Lei Li, Fei Sun, Peng Liu and Gen Hua Yue*AbstractBackground: The major fatty acids in seed ... genes. Conclusions In conclusion, we identified 18 QTLs underlying the oil traits and 3 eQTLs of the oleosin acid genes. Amongthem, qC18:1-1, qOilC-4 and qOleIII -5, controlling oleicacid, total oil content and ... Tofind as many putative QTLs (eQTLs) as possible, and toobtain a clearer understanding of the relationshipsamong examined traits, a threshold eQTL analysis of oleosin genes in of 2.0 for declaring...

báo cáo khoa học: " Modification of tobacco plant development by sense and antisense expression of the tomato viroid-induced AGC VIIIa protein kinase PKV suggests involvement in gibberellin signaling" doc

... tobacco plant development by sense and antisense expression of the tomato viroid-induced AGC VIIIa protein kinase PKV suggests involvement in gibberellin signalingRosemarie W Hammond* and Yan ... PKV gene by antisense expression resulted in a taller stature and increased numbers of influorescences in transgenicplants. The combined results of reversal of stunting in plants over expressing PKV ... roles in auxin signalling and plant cell death, respectively.To better understand the biological role of PKV in plant development, we introduced sense and antisense copies of the full-length pkv...

Báo cáo khoa học: "Intensive care unit delirium is an independent predictor of longer hospital stay: a prospective analysis of 261 non-ventilated patients" ppt

... non-venti-lated ICU patients.ã Even after adjustment for relevant covariates, delirium was found to be an independent predictor of longer hospital stay. While univariate analysis found an associ-ation ... to conduct this investigation.References1. American Psychiatric Association: Diagnostic and Statistical Man-ual of Mental Disorders Washington, DC: American PsychiatricAssociation; 1987. ... manuscript has: made substantial contribu-tions to conception and design, acquisition of data, and the analysis or interpretation of data; been involved in drafting thearticle or revising it critically...

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