Báo cáo khoa học: "B6C3F1 mice exposed to ozone with 4-(N-methyl-Nnitrosamino)-1-(3-pyridyl)-1-butanone and/or dibutyl phthalate showed toxicities through alterations of NF-κB, AP-1, Nrf2, and osteopontin" pdf

... 131–137B6C3F1 mice exposed to ozone with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and/ or dibutyl phthalate showed toxicities through alterations of NF-κB, AP-1, Nrf2, and osteopontinMin ... indicatetreatment of mixture of toxicants increased toxicity through NF-κB, AP-1, Nrf2, and OPN. Our data could be applied to the elucidation of mechanism as well as the risk assessment of mixture-induced toxicity.Key ... both mice sexes exposed to the combination of ozone, NNK, and DBP for16, 32, and 52 wk compared to single exposure to ozone, NNK or DBP [25,26]. Thus, high mutations and decreaseddegradation of...

Báo cáo khoa học: "A Functional Approach to Generation with TAG " pptx

... is not one of the arguments to the top level process. Thus a standard declarative form should be chosen for the realization of this top level element. Standard implementations of systemic ... more practical to replace the use of such realization operators with a more formal grammat- ical system (and that the use of such a system is perfectly consistent with the tenets of systemic ... Mumble-86. 3 Generator Architecture There are many different ways of imple- menting a TAG-based generator. We consider the principles that we take to be common to any TAG generator and indicate...

báo cáo khoa học: " Absorption and translocation to the aerial part of magnetic carbon-coated nanoparticles through the root of different crop plants" potx

... in tomato. h) Detail of a longitudinal section in wheat after 48 h of exposure to bioferrofluid. i) Detail of a crosssection of the first internode of pea after 24 h of exposure to bioferrofluid. ... Idem in tomato. d) Crown of wheat after 24 h of exposure, showing an intense accumulation of bioferrofluid in tissues. e) Detail of the crown of pea after 48 h of exposure to bioferrofluid.f) ... Idem in tomato. l) Detail of a cross section of the first internode of pea after 48 h of exposure to bioferrofluid. m) Idem in sunflower. n) Idem in tomato. o) Detail of a cross section of thesecond...

Báo cáo khoa học: "Molecular analysis of hprt mutation in B6C3F1 mice exposed to ozone alone and combined treatment of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and/or dibutyl phthalate for 32 and 52 weeks" ppsx

... by our groupon B6C3F1 mice exposed to 0.5 ppm ozone for 12 weekrevealed 0.5 ppm ozone was genotoxic to the exposed mice [20]. Moreover, we also showed that additive and/ or synergistic responses ... occurred when both mice sexes were exposed to ozone, NNK, and DBP, and the combination of ozone, NNK, and DBP through chromosome aberration and supravital micronucleus assays in 16-, 32-, and 52-wkstudies ... responsible for toxicity and combined exposure to ozone, NNK, and DBP inducesadditive genotoxicities compared to ozone alone.Key words: Ozone, NNK, DBP, hprt mutationIntroduction Ozone is the...

Báo cáo khoa hoc:"Analysis of response to 20 generations of selection for body composition in mice: ﬁt to inﬁnitesimal model assumptions" pdf

... articleAnalysis of response to 20 generations of selection for bodycomposition in mice: fit to infinitesimal model assumptionsVictor MARTINEZ∗, Lutz BÜNGER, William G. HILLInstitute of Cell, Animal and ... was twice and in the L lines half that of C. A log transformationremoved both asymmetry of response and heterogeneity of variance among lines, and so was used throughout. Estimates of genetic ... is the vector of fixed effects (gener-ations, generations × replicates and the regression of GFPR on litter size atweaning), a is the vector of additive genetic effects, f is the vector of full-sibfamily...

Tài liệu Báo cáo khoa học: Exposure of IgG to an acidic environment results in molecular modiﬁcations and in enhanced protective activity in sepsis doc

... 1B).Enhanced binding of low-pH buffer -exposed IVIg to recombinant human interferon-c (IFN-c) and other self-antigensInteractions of IVIg with cytokines and other mole-cules of the immune system ... < 0.05) stronger binding to this human proinﬂam-matory cytokine (Fig. 1C). Next, the reactivity of native and of low-pH buffer (pH 2.8) -exposed IVIgtowards a panel of structurally unrelated ... buffer- exposed IVIg to recombinant human IFN-c. (D) Increased binding of low-pH buffer -exposed IVIg to human factor H. In both panels, binding of the native IVIg is indicated by a solid line, and...

Tài liệu Báo cáo khoa học: Khai thác yếu tố ngôn ngữ trong giảng dạy văn học Việt Nam sau năm 1975 doc

...

Tài liệu Báo cáo khoa học: What MAN1 does to the Smads TGFb/BMP signaling and the nuclear envelope Luiza Bengtsson pdf

... cancer, ﬁbrosis and autoimmune disorders. Signa-ling is initiated by binding of the cytokine to ahomodimeric complex of cytokine receptor type II,which recruits type I receptor and activates ... cell type and signal-speciﬁc transcription acti-vators or repressors. There are three classes of Smads:regulatory Smads (BMP-responsive R-Smads 1, 5 and 8 and TGFb-responsive R-Smads 2 and 3), ... signal is conferred by mixing and matching of receptor subtypes in the oligomeric recep-tor complexes as well as by regulation of Smad interac-tions in the cytoplasm and in the nucleus. Smads canbe...

Tài liệu Báo cáo khoa học: An immunomodulator used to protect young in the pouch of the Tammar wallaby, Macropus eugenii pptx

... 1.CCK-8 and caerulein bind to CCK receptors [42].There are two types of CCK receptor, CCK1 and CCK2, differing in anatomical locations and actions[43]. The sequences of the CCK receptors are ... 1).Synthesis of eugeninEugenin was synthesized to conﬁrm the structure of the compound, and to provide sufﬁcient material to allow biological testing to be performed.The synthesis of tyrosine ... MS and MS ⁄ MS data onthe components of all HPLC fractions indicate thepresence of a variety of lipid, sugar and phosphateFig. 1. The young of Macropus eugenii (A)climbing into the pouch and...

Tài liệu Báo cáo khoa học: "Fine-grained Tree-to-String Translation Rule Extraction" docx

... Bottom-up decoding tree -to- string string -to- tree Figure 1: Illustration of the training and decod-ing processes for tree -to- string and string -to- treetranslations.fJ1is a sentence of ... times with “ko-roshita” and 1 time with “korosareta”; and “VBN(killed:passive)” appears 1 time with “ko-roshita” and 3 times with “korosareta”. Now, byattaching the voice information to “killed”, ... are neither descendantsnor ancestors of n. span(n) and comp span(n) of each n can be computed by ﬁrst a bottom-upexploration and then a top-down traversal of Et.By restricting each fragment...

Xem thêm