Báo cáo sinh học: " Darwin and Huxley revisited: the origin of allometry" docx
Tài liệu Báo cáo khoa học: Osmosensing and signaling in the regulation of mammalian cell function docx
... integrin-dependent cell volume sensing and signaling integrates into the overall context of insulin signaling. Similarly, sensing of glutamine-induced hepatocyte swelling by integrinsfeeds into ... 2007 The Authors Journal compilation ª 2007 FEBS MINIREVIEW Osmosensing and signaling in the regulation of mammalian cell function Freimut Schliess, Roland Reinehr and Dieter HaăussingerClinic ... cell volume to a functional outcome.This minireview summarizes recent progress in the understanding of how osmosensing and osmosignaling integrate into the overall context of growthfactor signaling...
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Tài liệu Báo cáo khoa học: Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc docx
... as the products that they gave rise to.This revealed both the major and minor pathways for the metabolism of vitamin D3 by P450scc. Results Metabolism of vitamin D3 by P450scc Six different products, ... of D3 metabolism by P450scc were identified by MS and by examining their sub-sequent metabolism by P450scc. These products were 23-hydroxyvitamin D3, 17a-hydroxyvitamin D3 and 17a,20-dihydroxyvitamin ... pathways for the metabolism of vitamin D3 by P450scc and toidentify both major and minor products. NMR was car-ried out on two of the major products, and identifiedthem as 20,23-dihydroxyvitamin D3...
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Báo cáo khoa học: Flexibility and communication within the structure of the Mycobacterium smegmatis methionyl-tRNA synthetase Henrik Ingvarsson and Torsten Unge potx
... 2010 The Authors Journal compilation ê 2010 FEBS Flexibility and communication within the structure of the Mycobacterium smegmatis methionyl-tRNA synthetase Henrik Ingvarsson and Torsten Unge Department ... amide groups of Ile128 and Arg129.Despite these differences in the coordination of the res-idues in the tip, the fold of the loop is strikingly simi-lar. The rmsd for the Ca atoms of the residues ... aeolicus) and 292 ⁄ 306 (T. thermophilus) allow rotation of the KMSKS loop. The two positions of the loop correspond to a rotation of 90°.H. Ingvarsson and T. Unge Crystal structure of M. smegmatis...
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Báo cáo Y học: Ascidian arrestin (Ci-arr), the origin of the visual and nonvisual arrestins of vertebrate pdf
... the shutting-down of the downstream signaling [1–4]. Vertebrate arrestins can be divided into two classes; visual arrestins and nonvisual, b -arrestins. Visual arrestins arecomposed of rod- and cone -arrestins, ... in the evolutionary process to vertebrates the duplication of the prototype resulted in two different types of arrestins, visual and b -arrestins. If so, Ciona must haveonly one gene for arrestin. Fig. ... of the aminoacid sequence similarity and the position of the intron to the vertebrate type of arrestin (Fig. 1). Therefore, it may bepresumed that the function was lost in vertebrate visual arrestin...
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Báo cáo hóa học: " Endotoxin and CD14 in the progression of biliary atresia" ppt
... to investigate endotoxin levels in patients with BA and the relation of theselevels with the expression of the endotoxin receptor, CD14. Methods: The plasma levels of endotoxin and soluble CD14 ... of endotoxin stimulated CD14 production by hepatocytes in the early stage of BA for removal of endotoxin; whereas, endotoxin signaling likely induced liver injury and impaired soluble CD14 synthesis ... change of CD14 production in the liver and the subsequent effects on LPS-inducedliver injury during BA is not clear. In this study, we investigated the role of CD14 in BA-associated liver injury,...
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báo cáo sinh học:" Employment and sociodemographic characteristics: a study of increasing precarity in the health districts of Belo Horizonte, Brazil" pdf
... for Health Open AccessResearch Employment and sociodemographic characteristics: a study of increasing precarity in the health districts of Belo Horizonte, BrazilMaria Cristina Ramos de Vasconcellos ... competing interests.Authors' contributionsMC, AA and SB jointly formulated the study design. MCobtained the data. MC and AA were involved in the con-ceptualization, initial drafts and final ... gratefully acknowledge the assistance of Dra. Ana Flavia Mach-ado, Professor of Demography at the University of Minas Gerais, in analysis of the data and for her helpful comments and editing.This...
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báo cáo sinh học:" A framework for evaluating the impact of the United Nations fellowship programmes" ppt
... fruition of a fellowship programme mitigates these limitations byassessing the importance and contribution of each steponthelogicalpathwaytowards training impact andascertaining that the f ellowship ... behavior, and results) are the pre-trainingdomain of planning, design and implementation, andthelongtermimpact(’mega -impact ) following the training programme. A major advantage of the co ntribution ... 8:7http://www.human-resources-health.com/content/8/1/7Page 6 of 8 METH O D O LOG Y Open Access A framework for evaluating the impact of the United Nations fellowship programmesArie Rotem1, Michael A Zinovieff2, Alexandre...
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Báo cáo sinh học: " A critical assessment for the value of markers to gate-out undesired events in HLA-peptide multimer staining protocols" pot
... FMO staining, a staining with irrelevant MULTIMER, dupli-cate stainings with the CMV and Melan -A multimers. The staining with the irrelevant MULTIMER was usedas a negative control. At least ... 13 RESEARCH Open Access A critical assessment for the value of markers to gate-out undesired events in HLA-peptide multimer staining protocolsSebastian Attig1†, Leah Price2†, Sylvia Janetzki3, ... al.: A critical assessment for the value of markers to gate-out undesired events in HLA-peptide multimer staining protocols. Journal of Translational Medicine 2011 9:108.Submit your next manuscript...
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Báo cáo sinh học: " Macrophages and cytokines in the early defence against herpes simplex virus" potx
... replication in most organs, including the liver,spleen, and eventually the brain [284]. The disseminationof infection to the brain and the severity of infection of the peripheral organs depend in part ... of the host, it will be in both interests, including the virus,to settle the conflict amicably. Some important weapons of the unspecific defence and the early strikes and beginning battle during ... cycle of the virus. A little later, other cytokines such as IL-12, IL-18 and IFN-γ are produced and give rise to other weapons in the battle against the virus. They will, in turn, within the nextreplication...
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Báo cáo toán học: " Synthesis and anti-HSV-1 evaluation of new " docx
... (1a–k), and new three 3H-pyrido[2,3-b]pyrazolo[3,4-h]-1,6-naphthyridine derivatives (2a–c). 1 Synthesis and anti-HSV-1 evaluation of new 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridines and 3H-pyrido[2,3-b]pyrazolo[3,4-h]-1,6-naphthyridines ... acceptance. Fully formattedPDF and full text (HTML) versions will be made available soon. Synthesis and anti-HSV-1 evaluation of new 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridines and 3H-pyrido[2,3-b]pyrazolo[3,4-h]-1,6-naphthyridinesOrganic ... previously reported the synthesis, SAR studies, and evaluation anti-HSV-1 activity of 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridines. In the course of our search for new 1,6-naphthyridines derivatives...
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Báo cáo sinh học: " Darwin and Huxley revisited: the origin of allometry" docx
... 2007,110044::12931-12935.23. Darwin CR: Journal of Researches into the Natural History and Geology of the Countries Visited During the Voyage of H.M.S.Beagle Round the World, Under the Command of Capt. Fitz ... of this article isnot Thomas (Darwin s ‘Bulldog’), but his grandson Julian, the author of Problems of Relative Growth [1], brother of the novelist Aldous (Brave New World) and half-brother of ... the relative size of the larger fiddler crabclaw (chela; Figure 2a). When the weight of the large claw of the fiddler crab was plotted double logarithmically against the weight of the rest of...
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Báo cáo toán học: "Meet and Join within the Lattice of Set Partitions" doc
... replacement of n by n − 1andofrby r − r/(1 + r)n +O(n−2), is the formula stated as Theorem 3. the electronic journal of combinatorics 8 (2001), #R15 6 Meet and Join within the Lattice of Set PartitionsE. ... ,xit). The various xijare themselves partitions of a set Si⊆ [n]; the join (over j)ofthexijequals {Si} ;and = {Si:1≤ i ≤ } is apartition of [n].Once the definition of the set Qnthas ... are the nonempty intersections of the blocks of πjwith the set Si.In the other direction ←− ,letT be a set of the form (4), consisting of t-tuples of partitions xij. We know that each join...
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Báo cáo sinh học: "Efficient algorithms for training the parameters of hidden Markov models using stochastic expectation maximization (EM) training and Viterbi training" potx
... RESEARC H Open AccessEfficient algorithms for training the parameters of hidden Markov models using stochastic expectation maximization (EM) training and Viterbi training Tin Y Lam, Irmtraud M ... ) ( , ( ))=Π and EyLM E yX Xiiqs(, , ) (, , ( ))=Π.Proof: The proof for this theorem is very similar to the proof of theorem 1 for Viterbi training and thereforeomitted. The key differences ... EM 1 Stochastic EM 3 Stochastic EM 5 Viterbi Figure 8 Performance for the CpG island model.Theaverageperformance as function of the number of iterations for each training algorithm. The performance...
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Báo cáo sinh học: "A simulation study on the accuracy of position and effect estimates of linked QTL and their asymptotic standard deviations using multiple interval mapping in an F2 scheme" ppsx
... articleA simulation study on the accuracy of position and effect estimates of linked QTL and their asymptotic standard deviations using multiple interval mapping in an F2schemeManfred M a∗,YuefuLb, ... III. Means and empirical standard deviations of additive QTL effect estimates over 100 replicates of simulation models 1 and 2 and means and standard deviations of the estimated asymptotic standard ... effect estimates for multiple, linked and interacting QTL using multiple interval mapping in an F2popula-tion and to examine the confidence intervals based on the standard statisticaltheory.2....
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Báo cáo sinh học: "Precision and information in linear models of genetic evaluation" ppt
... the individual CDs found in selection index theory. Precision increases with heritability (table IVd). Original articlePrecision and information in linear models of genetic ... set of eigenvectors, since 0 is a linear function of I and the inverse of a linear function of I and L’(Z’MZ)L.- The CDs can be verified to be between 0 and 1: ... 0. Since the smallest eigenvalue pi is null, wehave: Information for a linear combinationThe distributions of linear combinations x’u and x’u)11 are:By the algebra in...
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