... (CD)—fed the control diet; (2) 3% coffee diet (3%Co)—fed a diet containing 3% of brewed coffee; (3) 6% coffee diet (6%Co)—fed a diet containing 6% of brewed coffee; (4) 0.04% caffeine diet (0.04%Ca),— ... cognitive function, our data show that chronic coffee consumption modulates the endogenous antioxidant system in the brain. Therefore, chronic coffee ingestion, through the protection of the ... according to the standards applied by the Brazilian Coffee Industry Association (ABIC). The content of caffeine in coffee powder was 12.5 mg caffeine/g of coffee (1.25%), determined by HPLC. Boiled,...