... andprogressive diseases that are characterized by selectiveand often symmetric loss of neurons in motor, sensoryand cognitive systems. Clinically relevant examples ofthese disorders are Alzheimer s ... melatonin-deacety-lating enzymes, which are either specific melatonindeacetylases [36] or less specific aryl acylamidases; aseserine-sensitive acetylcholinesterase has an aryl acy-lamidase side activity, melatonin ... tissues),glutathione reductase (GRoad), c-glutamylcysteine synthase, glucose 6-phosphate dehydrogenase [5,5,49,79–85]; hemoperoxidase ⁄ catalase,Cu-, Zn- and Mn-superoxide dismutases (SODs)...