... 100 100Minus pantoate 2Minus ATP 46 50Minus ATP, minus pantoate 3Minus ATP, minus Pi45Minus ATP, minus ADP 3Eqn (1)Complete system 20Minus pantoate 1Minus ATP NDMinus ATP, minus pantoate ... are able to synthesize panto-thenate de novo, whereas animals rely on pantothenate in their diet.Pantothenate synthetase (PS) catalyzes the last step in the biosynthesis of pantothenic acid, ... of14C-label into pantothenate to negligible levels in both the Eqns (1,2) systems. In contrast, removing ATPabolished the accumulation of [14C]pantothenate only in the Eqn (1) system, whereas the...