... indicates an important role of the TRB chain in fine-tuning TR affinity of Melan-A-specific T cells of melanoma patients and argues against the hypothesis thathigh affinity TRs against self-Ags, like ... comparedusing particular BV or BVBJ combinations. Of clinical rel-evance, the Glycine-Leucine-Glycine motif was detected in lymphocytes obtained from untreated patients, represent-ing spontaneous ... Zhou J, Dudley ME, Rosenberg SA, Robbins PF: Selective growth, in vitro and in vivo, of individual T cell clones from tumor-infiltrating lymphocytes obtained from patients withmelanoma. J Immunol...