... T, Nakanishi K,Shimada A, Uga M, Kurihara S, Kawabata Y, et al: Genetic associationbetween the interleukin-2 receptor-alpha gene and mode of onset of type 1 diabetes in the Japanese population. ... Candidate-geneapproaches have also demonstrated a role for the Idd3locu s in human celiac disease and RA [25], as well as inT1D [26,27]. Interestingly, neither the Idd3 locus, norany of the ... diabetes [69]. Additionally, the T cells found in the blood, whether it be in their reper -toire, function and state of activation, may not accu-rately reflect the status and behavior of theircounterparts...