báo cáo hóa học:" Treatment of stiff thoracic scoliosis by thoracoscopic anterior release combined with posterior instrumentation and fusion" potx

báo cáo hóa học:" Activation of human B cells by the agonist CD40 antibody CP-870,893 and augmentation with simultaneous toll-like receptor 9 stimulation" doc

... studies were designed by ELC, JR, and RHV and wereperformed by ELC. ELC and RHV wrote the paper together with RM and JR. RM provided all statistical analyses. Allauthors read and approved the final ... is agonistic and activates naïve and memory Bcells with properties consistent with licensed APC. B cellactivation with CP-870,893 can be further increased with TLR9 co-stimulation and can be ... both memory and naïve B cellscan be activated by the drug CP-870,893, and this CP-870,893 effect can be increased by the addition of CpGODN 2006. Naïve B cells, as defined by lack of CD27expression,...

báo cáo hóa học:" Serum high mobility group box-1 (HMGB1) is closely associated with the clinical and pathologic features of gastric cancer" pptx

... Thesensitivity and specificity of serum HMGB1 was 71% and 67% (cut-off value of 5 ng/ml) for thediagnosis of early gastric cancer, and 70% and 64% (cut-off value of 4 ng/ml) for the diagnosis of high-risk ... was 67% and 71%(cut-off value of 5.5 ng/ml), and 71% and 67% (cut-offvalue of 5 ng/ml). The sensitivity and specificity of serumCEA levels for the diagnosis of high-risk lesions was 39% and 76% ... 28% and 79% (cut-off value of 3 ng/ml), and 40% and 66%(cut-off value of 2.5 ng/ml), respectively. In contrast toCEA, the sensitivity and specificity of serum HMGB1 lev-els for the diagnosis of...

Báo cáo hóa học: " Quality of Life as reported by school children and their parents: a cross-sectional survey" docx

... psychiatry, and the KINDL for moreextensive and broad assessment of QoL in children.The primary aims of the study were to compare child and parent by proxy ratings of child QoL and to investigatefactors ... results of an analysis of unconditional random effects showed that only 3.6% of the total variance of the ILC LQ0-28 scores and 6.5% of the total KINDL Total QoL scores could be explained by differences ... the ILC by 1777 child and parent pairsFigure 3The prevalence of reported problems in percentages on the ILC by 1777 child and parent pairs. ***p < 0.001 χ2.Health and Quality of Life Outcomes...

Báo cáo hóa học: " Validity of gait parameters for hip flexor contracture in patients with cerebral palsy" pot

... conception and design. SJC, DGK, and SHL have been involved in acquisition of data,analysis and interpretation of data. SJC, KML and MSP drafted themanuscript. All authors read and approved ... analysis.Validity of kinematic and kinetic variables, and psoaslength in hip flexor functionThere are no gold standards for measuring hip flexorfunction during gait. Therefore, the validity of kinematic and ... palsy and was approved by the institutional review board. The study was designedto include a group of normal children and a group of patients with cerebral palsy. For the group of normalchildren,...

Báo cáo hóa học: " Effect of terminal accuracy requirements on temporal gaze-hand coordination during fast discrete and reciprocal pointings" doc

... update of the i nitial hand moto r plan on thebasis of an accurate encoding of the target location[13-15] and (i i) an accurate control of the final phase of the p ointing movement on the basis of ... between the end of thehand movement (n) and the onset of the gaze for the fol-lowing movement (n + 1). It was calculated as follows:OFFSET latency end of hand movement onset of gaze n 1 () ... response of eye and hand motor systems in pointing at a visual target. I. Spatio-temporal characteristics of eye and hand movements and theirrelationships when varying the amount of visual...

báo cáo hóa học: "Usability of a virtual reality environment simulating an automated teller machine for assessing and training persons with acquired brain injury" pdf

... in persons with ABI, whilethe second compared the effects of using the VR-ATMprogram with those of using CAI when training persons with ABI to operate ATMs for cash withdrawals and money transfers. ... of cash withdrawals and money transfers using a real ATM were used to measure average reaction time, percentage of incorrect responses, level of cues required, and time spent as generated by ... sensitivity of the VR-ATM was 100% for cash withdrawals and 83.3% for money transfers, and the specificity was 83% and 75%, respectively. For cash withdrawals, the average reaction time of the VR...

báo cáo hóa học: " Inhibition of microglial inflammatory responses by norepinephrine: effects on nitric oxide and interleukin-1β production" pdf

... NOS2expression (assessed by nitrite and nitrate accumulation, NO production, and NOS2 mRNA levels) and IL-1β release (assessed by ELISA). Effects of NE were examined by co-incubating cells with different ... is formed by reaction of NO with superoxide, we used oxidation of H2DCF as a marker of NO production. Briefly, cells were activated by LPS for dif-ferent periods of time. At the end of each ... are mediated by β2-ARs and may involve cAMPThe inhibition of nitrite accumulation by NE was mim-icked by the β-AR agonist isoproterenol used between 0.1 and 10 µM (Figure 4A), and by the cAMP...

báo cáo hóa học: " Inhibition of NF-κB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia" docx

... h of reperfusion after 20 min MCAO. The results are presented as mean ± SD of normalized expression of target gene with respect to GAPDH mRNA from three sets of ani-mals. (C) Treatment with ... is one of the leading causes of death worldwide and a major cause of morbidity and mortality in the United States of America. Brain ischemia-reperfusion (IR) triggers acomplex series of biochemical ... both in vivo and in vitro.Results and discussion: Both pre- and post -treatment with BW-B 70C reduced infarctions and improved neurological deficit scores. Immunohistochemical study of brain sections...

báo cáo hóa học: " Inhibition of secreted phospholipase A2 by neuron survival and anti-inflammatory peptide CHEC-9" docx

... elevation of sPLA2s are associ-ated with most forms of inflammation [1-5]. The secretedisoforms are part of a growing family of PLA2 enzymeswhose activity leads to the production of several ... study were approved by both the Institu-tional Animal Care and Use Committee and by Institutional Review Board of Drexel University College of Medicine. Blood samples were treated with citrate-phos-phate-dextrose ... direction of change of Km and Vmax was the same fol-lowing inhibitor treatment, and Ki was less than 100 nM.Km and Vmax and r2 were determined with regressionsoftware (Prism) from Graphpad...

báo cáo hóa học: " Activation of retinal microglia rather than microglial cell density correlates with retinal neovascularization in the mouse model of oxygen-induced retinopathy" ppt

... design of the study and performed the statistical analysis. HTA conceived of the study, and participated in its design and coordination and helped to draft themanuscript. All authors read and approved ... microglial cells are oftenfound in close association with blood vessels, suggestingan interaction of microglial and vascular cells.One of the best-known mediators released by micro-glial cells ... ramified cells to cells with short and broad processes (see flat mounts). E and F arethe same as C and D, respectively, with the red channel omitted.Fischer et al. Journal of Neuroinflammation...

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