Báo cáo hóa học: " Postural adaptations to long-term training in Prader-Willi patients" pdf
Báo cáo hóa học: " Postural adaptations to long-term training in Prader-Willi patients" pdf
... home-based training on PWSindividuals was not effective in improving balance capacity. Possible causes of the lack of effectiveness of ourintervention include lack of training specificity, an inadequate ... effectiveness of the training. Our results are in contrast with those obtained byMaffiuletti et al [12] on morbidly obese individuals. In their study, specific balance training, in addition to abody weight ... due to their insatiable appetiteand food-seeking b ehavior. It could be speculated thatweight loss in addition to specific balance training ismandatory in order to improve balance capacity in PWS.Baseline...
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báo cáo hóa học:" CRP identifies homeostatic immune oscillations in cancer patients: a potential treatment targeting tool?" pdf
... might be able to assist the clinician by pin-pointing recurring opportunities to selectively enhance T-effectors and/or deplete or inhibit T-reg cells, in a cyclespecific manner, in the near ... purposes)CRP curve each vaccination had occurred. This allowed us to investigate the timing of vaccinations with respect to the CRP cycle, while examining the clinical responses.Since the periodicity ... thatbetter timing of administration of T-effector enhancing orT-reg depleting agents might be able to improve immuneresponses to break dominance of T-reg over T-effectorcells, to achieve consistent...
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báo cáo hóa học:" Main roads to melanoma" potx
... through an induction regulated by NF-kB, TNF-α, and INF-γ mediators) and expression levels of iNOS is shown. CALM, calmodulin; IkB, inhibitor of kB protein; IKK, inhibitor-of-kB-protein kinase; ... Extracellular-related kinase 1 or 2; IkB, inhibitor of kB protein; IKK, inhibitor-of-kB-protein kinase; MC1R, melanocortin-1-receptor; MITF, Microphthalmia-Associated Transcription Factor; MEK1/2, Mitogen-activated ... act in a common pathway leading to growth-arrest of nevi. In particular, the p16CDKN2A protein acts asan inhibitor of melanocytic proliferation by binding theCDK4/6 kinases and blocking...
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Báo cáo hóa học: " Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032" potx
... unresectablemelanoma inv olving the skin of the l eft chest wall, pro-gressing after treatment with topical imiquimod and sys-temic temozolomide, was referred to another institutionfor a phase II clinical ... cells in culture; HMK,participated in writing of the manuscript; DN, excised tumors and providedthe material for research; RH, in charge of analyzing tumor specimens andparticipated in writing ... mutations should be included in current and future trials of BRAF inhibitors.AcknowledgementsThis work was supported by the Yale SPORE in Skin Cancer funded by theNational Cancer Institute grant...
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Báo cáo hóa học: " The Armeo Spring as training tool to improve upper limb functionality in multiple sclerosis: a pilot study" ppt
... function training is often limited, princi-pally being indicated in highly disabled MS patients whohave a multiplicity of symptoms requiring treatment. Onthe other hand, training duration and training ... Spring training (n = 9)Variable BaselinevalueΔ after 24 training sessionspofΔ after 24 training sessionsΔ at 2-month follow-up,relative to baselinepofΔ at 2-month follow-up,relative to ... that completed the training program (n = 9) are presented in Table 1. Eachof them concluded all 24 training sessions within maxi-mal 9 weeks.Effects of the Armeo Spring training program on upperlimb...
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báo cáo hóa học: " Design strategies to improve patient motivation during robot-aided rehabilitation" docx
... obtained by summing the scores obtained in the tasks executed during each cycle of exercise lasting5 min. Finally, the Robot score was obtained by averagingthe four cycle scores obtained in ... neuro-adaptive control, hasbeen used to generate custom training forces to "trick"subjects into altering their target-directed reaching move-ments to a prechosen movement as an after-effect ... altered accordingly. The single taskscore was obtained by summing the scores obtained in each point to point reaching movement of the task (e.g.four reaching movements in the case of a square)....
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báo cáo hóa học: " Locomotor adaptation to a powered ankle-foot orthosis depends on control method" ppt
... intended uses includ-ing enhancing human performance in healthy individu-als, replacing motor capabilities in disabled individuals,and aiding in neurological rehabilitation. In each case,Published: ... improvemotor learning by enhancing errors in neuromuscularactivation patterns in a manner to that found by Patton etal.[25]. Future studies are needed to examine this possibil-ity.Competing interestsThe ... Sawicki GS, Domingo A, Ferris DP: The effects of powered ankle-foot orthoses on joint kinematics and muscle activation dur-ing walking in individuals with incomplete spinal cord injury.J Neuroeng...
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báo cáo hóa học: " Microglial responses to amyloid β peptide opsonization and indomethacin treatment" doc
... to insure that any failure ofindomethacin to affect chemotaxis to or phagocytosis ofAβ was not due to inadequate drug dosage. In some exper-iments, a 0.1 µg/ml concentration of indomethacin,which ... 4D).Microglial secretion of cytokinesConsistent with our previous studies covering a widerange of cytokines, chemokines, and inflammatory toxins[12], exposure of microglia to Aβ significantly enhancedsecretion ... ELISA(R&D Systems) using the manufacturer's protocols. To confirm the results with another pro-inflammatorycytokine, and to evaluate the interaction of indomethacinwith antibody opsonization,...
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báo cáo hóa học: " Brain microvascular pericytes are immunoactive in culture: cytokine, chemokine, nitric oxide, and LRP-1 expression in response to lipopolysaccharide" ppt
... (p38MAPK inhibitor, Tocris, USA), PD98059 (MAPKK/MEKinhibitor, Tocris, USA), UO126 (MEK-1/MEK-2 inhibi-tor, Tocris, USA), SP600126 (c-Jun N-Terminal kinaseinhibitor, Sigma, USA) and PTDC (NF-Binhibitor,Sigma, ... modified“biotin-switch” method. Specific mitogen-activated protein kinase (MAPK) pathway inhibitors were used to determine involvement of these pathways on NO production. Cytokines and chemokines were analyzed bymultianalyte ... isincreased in brain pericytes under inflammatoryconditions.Conclusions In conclusion, our results as presented here show thatcultured mouse brain pericytes secreting NO, cytokines,and chemokines...
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Báo cáo hóa học: " Evaluation of liver enzyme levels in workers exposed to vinyl chloride vapors in a petrochemical complex: a cross-sectional study" pot
... VCM.Demographic data including age, weight height, workexperience, alcohol consumption, tobacco smoking, pastmedical history, drug history, performing heavy exercises,work history including any changes ... damage in long-term. In this study we intend to assess the effects of mild to moderate long term exposure to VCM on liver and to assess theimportance of liver enzyme measurements as a screening tool.Methods: ... were usually in the normal range and our findings in fact show thechanges of these tests in working population. The clinicalimportance of these subtle changes of liver function in working populations...
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