báo cáo hóa học: " Primary Sjögren''''''''s Syndrome: health experiences and predictors of health quality among patients in the United States" potx
Tài liệu Báo cáo khoa học: "Finding Synonyms Using Automatic Word Alignment and Measures of Distributional Similarity" pdf
... and for applying the frequency cutoff. In the following section we describe the data and resources used in our experiments and finally the results of this approach.869Proceedings of the COLING/ACL ... of conveying the same in- formation in different ways are referred to by the term paraphrase and in the case of single wordssharing the same meaning we speak of synonyms.Identification of synonyms ... well-known combinatorialmeasure that computes the ratio between the size of the intersection of two feature sets and the sum of the sizes of the individual feature sets. Dice†is a measure that incorporates...
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Tài liệu Báo cáo khoa học: Cell surface heparan sulfate proteoglycans Target and partners of the basic ®broblast growth factor in rat Sertoli cells pptx
... 509 The bFGF binding requires speci®c motifs on highlysulfated HS chains. Sodium chlorate, in inducing structuralalteration of HS chains, prevents the bFGF binding. Ourresults indicate that the ... sequences of HS chains are de®ned for the bFGF binding and for the recognition of the speci®c bFGFreceptor, leading to the formation of a ternary complexcomprising HSPG±bFGF±FGFR. These oligosaccharidicmotifs ... cells were incubated for 24 heither in the absence or in prese nce of FSH, dbcAMP,cholera toxin or bFGF, either in combination with FSH ordbcAMP or cholera toxin and bFGF.Extraction of total...
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Báo cáo khoa học: Staphylococcus aureus elongation factor G – structure and analysis of a target for fusidic acid pdf
... affect the FA-binding pocket at the domain interface.Residues 666 and 670, within one b-strand of domain V, are also important for interdomain interac-tions. The N-terminal part of the strand interacts ... at the surface of EF-G and forms part of the FA-bindingsite, it points to the opposite direction in our structure,interacting with Glu93 in helix BG and Tyr126 in helixCG in the core of the ... Comparison of the positions of the tip of domain IV in all available EF-G structures in the PDB. The structures were superimposed on the basis of domains I and II. Looking from the direction of the...
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Báo cáo khoa học: Relation between domain evolution, specificity, and taxonomy of the a-amylase family members containing a C-terminal starch-binding domain pot
... evolution of this domain [30].This together with the findings of the present study indicatesa separate evolution of the domains C and E compared to the domains A and B. The recent introduction ... thick dashed line separates the amylase group from the CGTase group, while the thin dotted line indicates the change of the border between the two parts in the C domain tree and the SBD tree.Ó ... N-terminal part of the enzymes toone in uenced more by taxonomy at the C-terminal part of the same enzymes (Figs 3 and 4) can be seen in the presentstudy. The four- and five-domain members of GH...
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Báo cáo khoa học: "Viterbi Training for PCFGs: Hardness Results and Competitiveness of Uniform Initialization" doc
... of the string 10.A parse of the string sφusing Gφwill be usedto get an assignment by setting Yr= 0 if the ruleVYr→ 0 or V¯Yr→ 1 are used in the derivation of the parse tree, and ... self-training for parsing. In Proc. of HLT-NAACL.D. McClosky, E. Charniak, and M. Johnson. 2006b.Reranking and self-training for parser adaptation. In Proc. of COLING-ACL.R. McDonald and G. ... solving and even ap-proximating Viterbi training for PCFGs isNP-hard. We motivate the use of uniform-at-random initialization for Viterbi EM asan optimal initializer in absence of furtherinformation...
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Báo cáo khoa học: "A global model for joint lemmatization and part-of-speech prediction" doc
... (Collins, 2000).For training the joint model, we maximize the log-likelihood of the correct assignment to the words in LDev, marginalizing over the assign-ments of other related words added to the ... availability of a set of wordforms which are possible lemmas; in the no rootlist setting,no other word forms in the language are given in addition to the forms in the training set; in the complete ... and testing, which can inform the lemma-tization. The tagger is described in Section 4.2 and the transducer is described in Section 4.1. In a pipeline approach to combining the tagging and lemmatization...
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Báo cáo khoa học: Cas utilizes Nck2 to activate Cdc42 and regulate cell polarization during cell migration in response to wound healing docx
... and stained for GM130 to visualize the Golgi.Cells on the wound edge were divided equally into threesectors, including the front sector between the nucleus and the leading edge. The Golgi in ... tyrosine residues in the substrate-bindingdomain of Cas are phosphorylated in response to vari-ous extracellular stimuli, including integrin-mediated01020304050607080Ctrl CasCasActinCtrl ... pipette tip and incubatedfor 24 h. Data are the mean ± SD of the distance that leading edge of the monolayertraveled into the wound area in fiverandomly selected fields from threeindependent...
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Báo cáo khoa học: Etoposide upregulates Bax-enhancing tumour necrosis factor-related apoptosis inducing ligand-mediated apoptosis in the human hepatocellular carcinoma cell line QGY-7703 pdf
... function of TRAIL containing the extracellular domain (amino acids 114–281) of the human liver cancer cell line, QGY-7703 [27], we treated the cells with increasing concentrations of TRAIL and thenanalysed ... level of tBid.We also examined the expression of tBid and Bax bycombined treatment of TRAIL and etoposide; these resultsare shown in Fig. 4C. The protein levels of both tBid and Bax increased ... such as procaspase-9 and caspase-3,by binding to the inhibitor of apoptosis proteins and thusdisrupts linkage of the caspase–inhibitor of apoptosisproteins complex during apoptosis [48–50]....
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Báo cáo khoa học: From meiosis to postmeiotic events: Alignment and recognition of homologous chromosomes in meiosis ppt
... DNAs with DSBs and the con-sequent recombination are involved in homologysearching in S. cerevisiae [5]. On the other hand,homologous pairing is independent of recombination in many organisms ... formation and recombination of DNA,some residual levels of pairing still remain, suggestingthat a DSB-independent pairing mechanism may also beoperating in this organism [42–44].On the other hand, ... homologous DNAs involved in the process of homology searching and recombination along the chro-mosomes allow DSB-dependent pairing to occur [5].However, even in a mutant lacking Spo11 and other keyfactors...
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Báo cáo khoa học: Ets-1/ Elk-1 is a critical mediator of dipeptidyl-peptidase III transcription in human glioblastoma cells pdf
... Mutations of these binding sites abolished not only binding of the Ets protein, butalso the intrinsic promoter activity. Increased DNA-binding activity of Ets-1 ⁄ Elk-1 by v-Ha-ras also augmented the ... regulation of the gene. In thisregard, we identified the region that plays an impor-tant role in determining the basal promoter activity of the gene. Furthermore, with the help of binding assays and ... reported in brain homogenates of rat, monkey and guinea pig [5,7,16]. The presence of DPP-III in the central nervous system facilitates the degradation of angiotensins and encephalin, suggesting its...
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