... outcomes in several populations of patients, including critically ill patients. In a recent systematicreview of 45 observational studies reporting theimpact of transfusions on patient outcome ... cell transfusion in the ICUAnemia is common in ICU patients and appears early in the ICU course [1]. In an observational, multicenter,cohort study in Scotland, 25% of patients admitted tothe ... (e.g.,trauma, surgery, gastrointestinal bleeding), multipleother etiologies c ontribute to its pathophysiology and often coexist in the same patient [11]. These includeblood losses related to minor...