Báo cáo hóa học: "TAp73 is one of the genes responsible for the lack of response to chemotherapy depending on B-Raf mutational status" pot

... 36:4222-4232.doi:10.1186/1479-5876-8-15Cite this article as: Herreros-Villanueva et al.: TAp73 is one of the genes responsible for the lack of response to chemotherapy depending on B-Raf mutational status. Journal of Translational ... came to the conclusion that if TAp73 is regulateddifferently depending on the B-Raf status, this could bea good reason for the lack of response to chemotherapy when B-Raf is mutated. When B-Raf ... of Translational Medicine 2010, 8:15http://www.translational-medicine.com/content/8/1/15Page 5 of 8RESEARC H Open AccessTAp73 is one of the genes responsible for the lack of response to chemotherapy...

Báo cáo hóa học: " Could sound be used as a strategy for reducing symptoms of perceived motion sickness?" docx

... one in the non-positioned sound and one in the sound horizon, with aminimum of one week apart. They were not informedabout which experimental condition they were exposed to until after they ... a few sessions depending on the duration of the exposure [10].Considerable research has been devoted to identifying the specific autonomic responses associated with symptoms of motion sickness ... in the analysis of the resultsand preparation of the manuscript. AS participated in the experimental trials, were responsible for the statisticalanalysis and participated in the drafting of the...

báo cáo hóa học:" PAR1 is selectively over expressed in high grade breast cancer patients: a cohort study" docx

... Johnston M, PassH: International Registry of Lung metastases Results of lungmetatarsectomy from breast cancer: prognostic criteria on the basis of 467 cases of the International Registry of lungmetastases. ... andinterpretation of the data. TAV has been involved in the analysis of the immnuohistochemistry data, and helpwith the interpretation of the data. VMP Also have beeninvolved in the analysis and interpretation ... from time of diagnosis to dead. The follow up period began at the date of diagnosis. Patients were followed until death or cen-sored from this analysis at the time of their last visit to ourInstitution.ImmunoblottingWe...

báo cáo hóa học:" Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson''''s disease" doc

... high potassium (56 mM K+) and the buffer was subjected to HPLC assay.HPLC analysis of the synthesis and release of DA by RPE cellsFigure 5HPLC analysis of the synthesis and release of DA ... and synthesize DADDC is an enzyme that converts L-dopa to DA; the expres-sion of DDC indicates the RPE cells have the ability to produce DA. To determine whether the RPE cells can syn-thesize ... neurodegenerative disorder whichaffects approximately 1% population over the age of 60[1]. The most motor symptoms of this disease are causedby dysfunction of the nigro-striatal pathway. DAergic neu-rons...

báo cáo hóa học:" Mass spectrometry-based serum proteome pattern analysis in molecular diagnostics of early stage breast cancer" pdf

... by aster-isks).Estimation of the performance of classification of breast can-cer samplesFigure 1Estimation of the performance of classification of breast cancer samples. A – The total error ... value of 50 the corresponding spectral component wasexcluded from further more detailed analyses. Based on the decomposition of the average mass spectrum into the Gaussian components, the classifier ... advantage of genomics and proteomics, novel fields of modern biology. Proteomics is the study of the pro-teome, the complete protein components of the cell, tis-sue or organism, which in contrast to...

báo cáo hóa học:" Protective versus pathogenic anti-CD4 immunity: insights from the study of natural resistance to HIV infection" potx

... diseases. The depletion of the CD4 T lymphocytes is the hallmark of the progression of HIV infection and, in the absence of antiviral treatment, the main contributor to the development of opportunisticinfections ... arthritis the developmental pattern of arthritis differed substantially between three distinctmonoclonals, two of them preventing, the third one accel-erating the development of the disease ... generation of various self-epitopes, which in the absence of HIV are ignored due to tolerance mecha-nisms. In fact, the formation of Env (gp160)-CD4 com-plexes in the ER can lead to their retention...

Báo cáo hóa học: " Adenoviruses with an avb integrin targeting moiety in the fiber shaft or the HI-loop increase tumor specificity without compromising antitumor efficacy in magnetic resonance imaging of colorectal cancer metastases" pdf

... residues of the fiber bindingmotif has been suggested to avoid vector ending into the liver hepatocytes but this modification has beenshown to be an inadequate to change the biodistribution of the ... were d one with SPSS 15.0 for Windows. One- way analysis of variance (ANOVA) followed byDunnett’s Pairwise Multiple Comparison t-test was used to analyze the differences in the cell killing potency ... production of most of the viruses used for this article. Especially, we thank Prof. Alemany for his advice during the development of this work. We thank Eerika Karli,Aila Karioja-Kallio, Sirkka-Liisa...

Báo cáo hóa học: " Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice" doc

... decided to test the effects of cortisol receptor blockade using the drug mife-pristone (RU486). Mifepristone is a progesterone analo-gue that can act as an antagonist for the glucocorticoidreceptor ... tumors formed in C57BL/6mice. With the addition of mifepristone treatment to the Ad5IL-12 vector, cytotoxic activity in the TSLN is enhanced. These results indicate that the inclusion of RU486 ... addi-tion of RU486 (mifeprist one) in combination with intra-tumor injection of Ad5IL-12 vector can enhanceprostate cancer therapeutic efficacy versus that of vectortherapy alone. The inclusion of...

báo cáo hóa học: " Fatness and fitness: how do they influence health-related quality of life in type 2 diabetes mellitus?" docx

... approval for the version to be published. AW contributed to the development of the analytic plan and editing the manuscript has given finalapproval for the version to be published. BB contributed to ... stage one hypertension (defined assystolic blood pressure (BP) of 130–159 and/or diastolicBP of 85–99 mm Hg). Subjects who were using only one medicine for hypertension were allowed to discontinuetheir ... contributed to the development of the analytic plan and editing the manuscript and has given final approval for the version to be published. KS was the principal investigator for the twotrials that this...

báo cáo hóa học: " Struggles, strengths, and strategies: an ethnographic study exploring the experiences of adolescents living with an ostomy" doc

... like the plastic ring. So I'm justafraid that someone is going to feel it and say 'what is that?'." " one of my friends went like this to my stomachand one of (her) ... experi-ence in the information and support needs of this popu-lation, and was involved in various elements of the study.AMG is a staff gastroenterologist in the Division of Clini-cal Nutrition and ... adolescent reflected on a hospitalization, andplaced responsibility upon himself for the deprivation of the healthy sibling's time with the parent." ;One time I went to the hospital, I was...

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