... the NBD than ATP. Rapid dissociation of hydrolysis productmay be expected as part of the kinetics of the transport cycle of the intact transporter. Furthermore, the data demon-strate that the ... determinations of both intact ABC transportersand NBD proteins also lend weight to asymmetry in theseproteins. The crystal dimer of the NBD of the maltose- uptake system of Thermococcus littoralis (MalK) ... Schnell,C.,Vonrhein,C.,Boos,W.&Welte,W.(2000)Crystalstructure of MalK, the ATPase subunit of the trehalose /maltose ABC transporter of the archaeon Thermococcus litoralis. EMBO J. 19,5951–5961.45. Hopfner,...