... UMP kinase from the Gram-positive bacterium Bacillus subtilis is strongly dependent on GTP for optimal activity Cristina Gagyi1, Nadia Bucurenci2, Ovidiu ... demonstrating the ability of the encoded protein to synthesize UDP [18].These observations reopened the question of the roleplayed by UMP kinase in the metabolism of B. subtilis, and in Gram-positive ... UMP kinase from B. subtilis is conserved in the enzyme from S. aureus, Pseudomonas aeruginosa, Bordetella pertussis,Mycobacterium tuberculosis, Neisseria meningitidis, Chla-mydia trachomatis...