Báo cáo Y học: Potential active-site residues in polyneuridine aldehyde esterase, a central enzyme of indole alkaloid biosynthesis, by modelling and site-directed mutagenesis ppt
Báo cáo Y học: Potential active-site residues in polyneuridine aldehyde esterase, a central enzyme of indole alkaloid biosynthesis, by modelling and site-directed mutagenesis ppt
... Potential active-site residues in polyneuridine aldehyde esterase, a central enzyme of indole alkaloid biosynthesis, by modelling and site-directed mutagenesis Emine Mattern-Dogru1, Xueyan ... Mechanistic aspects of the reaction catalyzedwere investigated by site-directed mutagenesis, replacing theamino acids of the putative catalytic triad and individualcysteine residues by alanine ... H1 7A: 5¢-GCATTTTGTTCTGGTACACGGCGGATGTCTCGGAGCTTGG-3¢.H-8 6A: 5¢-GGTTGTTCTTCTTGGCCATAGCTTTGGTGGCATGAGTTTGGG-3¢. S8 7A: 5¢-GTTCTTCTTGGCCATAGCTTTGGTGGCATGAGTTTGGG-3¢. H24 4A: 5¢-CAAAGAAGCAGATCATATGGGAATGCTTTCGCAGCCAAGGG-3¢. D21 6A: 5¢-GCGAGCTTATATCTTTTGCAATGAAGATAAATCATTTCCAGTTGAG-3¢All of the primers...
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Báo cáo y học: "Electronic patient record use during ward rounds: a qualitative study of interaction between medical staff"
... complex nature of interaction of multidisciplinarycommunication in an ICU, we have chosen to triangulate threetypes of qualitative data: video-based interaction analysis,observation, and interviews. ... onachieving a conversation, on being wary that formation affectsinteraction and that the substantial amount of information in the EPR might distract rather than add to the interaction, and on encouraging ... observation chart, the drugchart, and the plan of the day) and a folder or binder for mis-cellaneous and patient-specific forms and papers. The obser-vation chart was A3 -size paper that lay flat...
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Báo cáo khoa học: "Veterinary decision making in relation to metritis - a qualitative approach to understand the background for variation and bias in veterinary medical records"
... time are central to minimizingvariation and bias, regardless of the later use of the datafor quantitative analyses. Definitions of accuracy and pre-cision here are defined in accordance with ... consequences of variation and bias in relation to monitoring of animal disease incidence onherd and national level, causal analysis on national level,as well as estimation of validated treatment ... level. Potential consequences of bias and variation in veterinary recordsVeterinary medical records can be applied in the dairy sec-tor in many ways and for many reasons. In the followingwe will discuss...
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Báo cáo Y học: Conformationally constrained human calcitonin (hCt) analogues reveal a critical role of sequence 17–21 for the oligomerization state and bioactivity of hCt ppt
... potencies in vivo of hCt,sCt, analogues 1–6 and/ or 1a, 1b, 2a, and 3a are summa-rized in Table 1. Our findings that 3 and 4, that contain typeIandII¢ b-turn-promoting substitutes, had the samehypocalcemic ... Biologically ac tive cyclic (lactam) analogs of growth hormone-releasing factor: Effect of ring size and locationon conformation and biological activity. In Pe ptides: Chemistr y and Biology (Smith, ... constrained human calcitonin (hCt) analoguesreveal a critical role of sequence 17–21 for the oligomerizationstate and bioactivity of hCtAthanasios Kazantzis1, Michaela Waldner1, John W. Taylor2and...
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Báo cáo Y học: Extra terminal residues have a profound effect on the folding and solubility of a Plasmodium falciparum sexual stage-specific protein over-expressed in Escherichia coli pptx
... Pfg27D:5¢-AAAGAATTCATGAGTAAGGTACAAAAG-3¢ and 5¢-AAACTGCAGTTAAATATTGTTGTGATGTGGTTCATC-3¢ (EcoRI-PstI); Pfg27E:5¢-AAACTGCAGATGAGTAAGGTACAAAAG-3¢ and 5¢-AAAAGCTTTCACTTCGAATTCCATGGTACCAG-3¢ (PstI-HindIII); ... Pfg27B:5¢-AAACTGCAGATGAGTAAGGTACAAAAG-3¢ and 5¢-AAACTGCAGTTAAATATTGTTGTGATGTGGTTCATC-3¢ (PstI); Pfg27C:5¢-AAAAAGCTTATGAGTAAGGTACAAAAG-3¢ and 5¢-AAAAAGCTTTTAAATATTGTTGTGATGTGGTTCATC-3¢ (Hin-dIII); ... sites are shown in bold and the respective enzymes in parentheses): Pfg27 A :5¢-AAACTGCAGATGAGTAAGGTACAAAAG-3¢ and 5¢-AAAAAGCTTAATATTGTTGTGATGTGGTTCATC-3¢ (PstI-HindIII); Pfg27B:5¢-AAACTGCAGATGAGTAAGGTACAAAAG-3¢...
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Báo cáo y học: "Emergency intraosseous access in a helicopter emergency medical service: a retrospective study"
... contributionsGAS and JKH conceived the study and participated in its design and coordination, and in drafting the manuscript. BEH participated in the design of the study and the statistical analysis, and participated ... (SPSS Inc., Chicago, IL, USA) and Statistical Analy-sis System (SAS) version 0.2 software for Windows (SASInstitute, Inc., Cary, North Carolina). Exact confidenceintervals were obtained by using ... participated in drafting themanuscript. BHV participated in the design of the study, and the drafting of the manuscript and tables and figures. All authors have read and approvedthe final manuscript.Competing...
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Báo cáo y học: "Iraqi health system in kurdistan region: medical professionals’ perspectives on challenges and priorities for improvement"
... provided and facilities available at their workinginstitutions including the quality of offered health ser-vices, availability of the required quantity and quality of medicines, availability of medical ... selection of participants and contacting them was logistically difficult especiallythat no funds were available for this study. A statisticallyrepresentative sample size of medical professionals in Erbil ... Falah H Shwani2, Abubakir M Saleh1, Tariq S Al-Hadithi1AbstractBackground: The views of medical professionals on efficiency of health system and needs for any changes arevery critical...
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Báo cáo y học: "Strict glycaemic control in patients hospitalised in a mixed medical and surgical intensive care unit: a randomised clinical trial"
... infections in the ICU (ventilator-associated pneumonia, uri-nary infections, catheter-related infections and primary bacter-aemias); ICU length of stay; days of mechanical ventilation and incidence of ... Intensive insulin therapydecreases morbidity and mortality rates in patients in a surgicalintensive care unit (ICU) and decreases morbidity in patients in a medical ICU. The effect of this therapy ... González3, Nora Elena Saldarriaga4, Marisol Bedoya1, Juan Manuel Toro5, Jorge Byron Velásquez4, Juan Carlos Valencia4, Clara Maria Arango5, Pablo Henrique Aleman1, Esdras Martin Vasquez4,...
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Báo cáo y học: "Line bisection performance in patients with generalized anxiety disorder and treatment-resistant depressionLine bisection performance in patients with generalized anxiety disorder and treatment-resistant depression"
... China; 2. Department of Clinical Psychology and Psychiatry, Zhejiang University School of Medicine, Hangzhou, China; 3. Department of Psychiatry, Second Hospital, Zhejiang University School of ... Medicine, Hangzhou, China Corresponding author: Dr. Wei WANG, B.Med., D.Sc.; Department of Clinical Psychology and Psychiatry; Zhejiang University School of Medicine; Yuhangtang Road 388; Hangzhou, ... the associa-tion of left hemisphere predominance and risk-taking in healthy university students has also proven by studying the line bisecting performance and Zucker-man’s sensation seeking...
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Báo cáo y học: "Ultra-low microcurrent in the management of diabetes mellitus, hypertension and chronic wounds: Report of twelve cases and discussion of mechanism of action"
... mellitus and cardiovascular diseases including hypertension. The low levels of antioxidants accompanied by raised levels of markers of free radical damage play a major role in delaying wound healing. ... complications (11-13). The combination of the low levels of antioxi-dants and raised levels of free radical play a major role in delaying wound healing in aged rate and dia-betic rats (14). ... CR, Carey AL, Hawley JA, Febbraio MA. Intramuscular heat shock protein 72 and heme oxygenase-1 mRNA are re-duced in patients with type 2 diabetes: evidence that insulin resistance is associated...
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