... effects of oxidationand acts as a redox sensor [8,13,32]. Oxidation of RPTPa-D2, like PTP1B, results in the formation of cyclic sulfenamide at the catalytic site, which is stableand reversible by ... role of oxidation in dimerization of a panel of fourdifferent RPTPs.We compared four RPTPs from different subtypes,i.e. RPTPa, RPTPl, CD45 and LAR. We found thatthe cytoplasmic domains of these ... ectodomains of LAR and RPTPl maydrive homophilic interactions [35–38]. To remove con-tributions of the ectodomains to dimerization, we gen-erated chimeras consisting of the extracellular domainof...