Báo cáo khoa học: "Learning Effective Multimodal Dialogue Strategies from Wizard-of-Oz data: Bootstrapping and Evaluation" pot

... 2008.c2008 Association for Computational LinguisticsLearning Effective Multimodal Dialogue Strategies from Wizard-of-Oz data: Bootstrapping and EvaluationVerena RieserSchool of InformaticsUniversity ... learned strategies are then available from theﬁrst moment of online-operation, and tedious hand-crafting of dialogue strategies is omitted. This inde-pendence from large amounts of in-domain dialogue data ... of dialogue strategies: learning effective dialogue strategies when noinitial data or system exists, and evaluating theresult with real users. We use ReinforcementLearning (RL) to learn multimodal...

Báo cáo khoa học: "Learning to Win by Reading Manuals in a Monte-Carlo Framework" pot

... addition to learn-ing game strategies guided by the selectedtext. Our method operates in the Monte-Carlosearch framework, and learns both text anal-ysis and game strategies based only on envi-ronment ... horizons, and high-branchingfactors, this approach can be prohibitively slow and ineffective. An algorithm with access to the text,however, could learn correlations between words inthe text and ... linguis-tic analysis from a situated context (Oates, 2001;Siskind, 2001; Yu and Ballard, 2004; Fleischman and Roy, 2005; Mooney, 2008a; Mooney, 2008b;Branavan et al., 2009; Vogel and Jurafsky, 2010).Within...

Báo cáo khoa học: "A Statistical Spoken Dialogue System using Complex User Goals and Value Directed Compression" pptx

... Statistical Spoken Dialogue System using Complex User Goals and Value Directed CompressionPaul A. Crook, Zhuoran Wang, Xingkun Liu and Oliver LemonInteraction LabSchool of Mathematical and Computer ... extends work presented byCrook and Lemon (2011) in that it embeds thecompressed complex user goal belief space into aworking system and demonstrates planning (and acting) in the compressed space.2 ... limited-domain query -dialogue, also known as a “slot ﬁll-ing” task. The spoken dialogue system has knowl-edge about some set of objects where these ob-jects have attributes and these attributes...

Báo cáo khoa học: "Learning Document-Level Semantic Properties from Free-text Annotations" pot

... distribution. The ﬁrst line follows from Bayes’ rule, and the second line from the conditionalindependence of each keyphrase assignment xℓ from the others, given ψ.φd and θkare resampled in a similar ... alternative strategies by a wide margin.2 Related WorkReview Analysis Our approach relates to previouswork on property extraction from reviews (Popescuet al., 2005; Hu and Liu, 2004; Kim and Hovy,2006). ... cd,n= 0 and cd,n= 1within a constant of proportionality, and then sample from the normalized Bernoulli distribution.6 Experimental SetupData Sets We evaluate our system on reviews from two...

Báo cáo khoa học: PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL pot

... cells and GC-derived malignantlymphoma cells. It inhibits interleukin-6 and SDF-1-induced migration of malignant lymphoma cells and normal GC B lymphocytes by interacting with actin and myosin ... and its downstream effectors by directlybinding and activating the RhoA-speciﬁc guanine nucle-otide exchange factors PDZ-RhoGEF and LARG. Thisstimulates the GDP–GTP exchange rate of RhoA and results ... celllines downregulates endogenous mRNA and proteinexpression of both HGAL and LMO2.PRDM1 binds the HGAL and LMO2 promotersin vivoThe effect of PRDM1 on HGAL and LMO2 expres-sion could be through...

Báo cáo khoa học: Dynamics driving function ) new insights from electron transferring ﬂavoproteins and partner complexes pdf

... dimer of MCAD and ETF are shown for clarity. PDB code for all, 2A1T[25]. a- and b-ETF chains and MCAD are shown as magenta, blue and green cartoons, respectively. The cofactors FAD and AMP are ... product-boundpig ACAD and ETF at 3 °C is multiphasic, composedof two rapid phases (t1 ⁄ 2$ 20 and 50 ms) and twoslower phases (t1 ⁄ 2$ 1 and 20 s) (inset, Fig. 9) [60].The ﬁrst and second phases ... from humans (A) and Methylophilus methylotro-phus W3A1 (B). PDB codes: human, 1EFV[1]; W3A1, 1O96 [3]. a- and b-ETF chainsare shown as magenta and blue cartoons.FAD and AMP are shown as yellow and orange...

Báo cáo khoa học: Protein folding includes oligomerization – examples from the endoplasmic reticulum and cytosol doc

... dynamic and ﬂexible foldingfactory.The ER adapts to changingcircumstancesFusion and ﬁssionThe morphology of the ER is continuously and rapidlychanging in living cells, with tubules and sheets ... activation and timingof the stress sensors.Three main stress sensors reside in the mammalianER: Ire1a (and its homolog Ire1b), activating tran-scription factor 6a (ATF6a) (and its homolog ATF6b) and ... [215], and unspliced XBP1 canform a complex with the transcription factor encodedby spliced XBP1, thereby sequestering it from thenucleus and attenuating the UPR [216]. Pathways dif-ferent from...

Báo cáo khoa học: Molecular imprinting of cyclodextrin glycosyltransferases from Paenibacillus sp. A11 and Bacillus macerans with c-cyclodextrin pptx

... to 6 and 8 to 11, whereas the immobilized and CLIP CGTases from BM showed higher stability inthe ranges from 3 to 7 and 9 to 11 (data not shown).The activities of the native, immobilized and ... range from 8 to 11 was observed. This effect wasmore pronounced with the CGTase from BM. Theimmobilized and the CLIP CGTase from A11 weremore stable than the native enzyme in the pH ranges from ... differentCGTase preparations from A11 and BM wasTable 1. Degree of derivatization of the CGTases from A11 and BM obtained with different protein ⁄ itaconic anhydride ratios and remaining cyclization...

Báo cáo khoa học: Multiple effects of DiS-C3(5) on mitochondrial structure and function pot

... mitochondrial structure and function.Materials and methodsMaterialsDiS-C3(5) and cyclosporin A (CsA) were kindly providedby Hayashibara Biochemical Laboratories, Inc. (Okayama,Japan) and Novartis ... mitochondrial membrane potentialhave the dual effects of (i) inhibiting complex I and (ii) inducing the mitochondrial PT, even though theirchemical struc tures are markedly different from each other.In ... small solutes and ions. However, under certainconditions, such as in the presence of Ca2+ and inorganicphosphate (Pi), the inner mitochondrial membrane becomespermeable to solutes and ions up...

Báo cáo khoa học: Characterization of c-tocopherol methyltransferases from Capsicum annuum L and Arabidopsis thaliana pptx

... [14C]AdoMet(1.85 MBq) was from Pharmacia Biotech (Freiburg, Ger-many) and unlabelled AdoMet and AdoHcy were from Sigma. Chromatographic materials and columns wereobtained from Bio-Rad (hydroxyapatite), ... wereobtained from a local market.ChemicalsThe (+) c -and( +) d-tocopherols were purchased from Sigma(Deisenhofen, Germany). Residual (+/–)-b-tocopherolswere obtained from Merck (Darmstadt, Germany) and additionally ... in plastid envelopes [7] from precursors originating from the plastidial isoprenoid path-way and from the shikimate pathway, providing thehydrophobic phytyl moiety and the polar head grouphomogentisic...

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