Báo cáo khoa học: Examining multiprotein signaling complexes from all angles The use of complementary techniques to characterize complex formation at the adapter protein, linker for activation of T cells pdf
Báo cáo khoa học: Examining multiprotein signaling complexes from all angles The use of complementary techniques to characterize complex formation at the adapter protein, linker for activation of T cells pdf
... alsointeract with LAT, but whether these proteins directly or indirectlyassociate with LAT is still controversial. The result of the formation of LAT-mediated complexes is the activation of signaling ... 5435MINIREVIEW Examining multiprotein signaling complexes from all angles The use of complementary techniques to characterize complex formation at the adapter protein, linker for activation of T cells Jon ... able to quantitatively examine the multiprotein complexes that form at LAT, provi-ding insights into the formation and function of these complexes that could not be observed using othermethods....
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Tài liệu Báo cáo khoa học: Long-distance interactions between enhancers and promoters The case of the Abd-B domain of the Drosophila bithorax complex pdf
... enhancer targeting in the Abd-B domain. The observation that the larger the deletion within this region, the stronger the resultingtrans regulation, indicates that the critical region isbuilt up from ... difference in the tim-ing of somatic pairing perhaps reflects the differencebetween the complexities of the regulation of the twosystems: a longer time is required for the formation of the complex ... accord-ing to the spatial activity pattern of the ‘early enhanc-ers’. These alternative chromatin conformations willeventually restrict the action of ‘cell-specific enhancers’ to segmental boundaries....
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Báo cáo khoa học: Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression docx
... the absence of STARS. The actin mutant that favorsF-actin formation and increases the F-actin ⁄ G-actinratio [56] stimulates MRTF activity, even in the absence of STARS, and abolishes further activation ... G-actin, but does not alter the F-actin ⁄G-actin ratio, reduced the ability of STARS to activateMRTF-dependent transcription. Wild-type actin didnot significantly alter the activity of MRTF in the absence ... interact physicallywith the AR to modulate its transcriptional activity,disruption of the AR–ABP interaction may be animportant strategy by which to regulate AR-mediatedgrowth of prostate cancer...
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Báo cáo khoa học: Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L-gulono-1,4-lactone dehydrogenase doc
... in vitro, eitherbecause its concentrations were below the detectionlimit or because of the lack of the l-gulono-1,4-lactonesubstrate in these cells. l-Gulono-1,4-lactone can beformed by the ... to determine the enzymatic activity of the GST-tagged Rv1771 protein of M. tuberculosis, the oxidase activity was tested in the presence of the l-gul-ono-1,4-lactone and l-galactono-1,4-lactone ... represent anovel weapon in the antioxidative arsenal of the pathogen at least in some, although still unknown,stages of M. tuberculosis infection. Interestingly, the promoter of the cell wall catalase-peroxidase...
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Báo cáo khoa học: UDP-galactose 4-epimerase from Kluyveromyces fragilis – catalytic sites of the homodimeric enzyme are functional and regulated docx
... inactive. This led to the assumption thatthere is regulation between the catalytic sites. Func-tionality could be restored after replacement of the inhibitor by a substrate [14]. Therefore, either ... circumference of the lobe next to the site indicates susceptibility to the protease; +UMP and –UMP indicate its association and dissociation; the arrow on the top of the schemeindicates the direction of ... of four tryptophans per subunit is located at the catalytic site [20]. Thus, perturbation of the catalyticsites is likely to be reflected in the fluorescence spectra of its tryptophans (excitation...
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Báo cáo khoa học: End-damage-specific proteins facilitate recruitment or stability of X-ray cross-complementing protein 1 at the sites of DNA single-strand break repair docx
... include identifica-tion of these lesions as a strand break, verification of the nature of the 3¢ end, and identification of a satis-factory pathway for repair. The XRCC1 component of the XRCC1–DNA ... specific protein that is required to progress the particular lesion to the next stage of repair. Therefore,Pol b initiates repair of single-nucleotide gaps, PNK isrequired for the initiation of repair ... to the gap-containing substrate to agreater extent than to the control substrate (Fig. 2A),indicating damage specificity of cross-linking. When 5¢-labelled gap-containing oligonucleotide attached...
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Báo cáo khoa học: "Are These Documents Written from Different Perspectives? A Test of Different Perspectives Based On Statistical Distribution Divergence" ppt
... document collection pairs. The little the overlap of the range of distribution di-vergence, the sharper the test of different perspec-tives. To account for large variation in the number of words ... Quality of Monte Carlo Estimates The Monte Carlo estimates of the KL divergence from several document collection pair are listed inTable 2. A complete list of the results is omit-ted due to the ... of θ between two posterior distributionsp(θ|A) and p(θ|B). The marginal distribution of the i-th coordinate of θ, that is, the i-th word in the vocabulary, is a Beta distribution, and thus the...
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Báo cáo khoa học: Functionally distinct dopamine and octopamine transporters in the CNS of the cabbage looper moth* potx
... does the moth OAT substitute for DAT in dopami-nergic signaling pathways in the moth CNS, and what is the nature of the mechanism that substitutes for OAT in the octopaminergic pathways in the ... indicating that the KTrnDATm for Na+must be greater than 100 mM,asseeninTrnOAT[12]. The uptake of [3H]DA by cells expressing TrnDAT andTrnOAT was inhibited by the five putative competitivetransport ... protein. The putative translational start site for this ORF was selectedbased on the presence of an in-frame stop codon locatedimmediately upstream of it. The protein encoded by the ORF (TrnDAT)...
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Báo cáo khoa học: Upstream and intronic regulatory sequences interact in the activation of the glutamine synthetase promoter pot
... differences in activity of the respective regulatory elements due to interactionsrather than in the use of distinct, tissue-specific regulatoryelements.Glucocorticoid sensitivity of the regulatory sequences All ... respect to their regulatory activity. To test this hypothesis, we examined the combinatorial effects of modular deletions in the distal upstream and first intronregions of the rat GS gene on reporter ... not shown).Correction for experimental variation and statistics The transactivation potential of the tested DNA con-structs was expressed as the ratio between their luciferaseactivity (light...
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Báo cáo khoa học: Cyclosporin A-induced oxidative stress is not the consequence of an increase in mitochondrial membrane potential doc
... during the transfer of these electrons is used to pump protons from the mito-chondrial matrix towards the inner membrane space,thereby creating a proton gradient. The energy storedin the proton ... accu-mulation between non-P-glycoprotein-containing cells and the same cells transfected in such a way that theyexpress this protein. We demonstrated that in cells thatdo not contain P-glycoprotein, ... mitochondrial ATP synthesis and respirationrate would be expected to alter. Our results showedthat neither ATP synthesis nor mitochondrial respir-ation rate was influenced by CsA, which is similar to the...
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Từ khóa: báo cáo khoa họcbáo cáo khoa học mẫubáo cáo khoa học y họcbáo cáo khoa học sinh họcbáo cáo khoa học nông nghiệpbáo cáo khoa học lâm nghiệpNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíQuản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Nguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMMÔN TRUYỀN THÔNG MARKETING TÍCH HỢPTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ