... section and scheme of the coronal section at E14.5 in (F). (A) At E11.5, HSF2 is expressed in forebrain, midbrain and in hindbrain except for the midbrain, hindbrain midline. Surprisingly, the ... of cHSF2,mHSF2 and rHSF2 are associated with nuclear locali-zation within the developing neural tube [3,62,121]. In addition, mHSF2 is associated with DNA binding in the developing brain, including ... abnormal mor-phology in correlation with increased proliferation,premature differentiation and elongation, inhibition of denucleation and of loss of organelles [101]. In line with this phenotype,...