Báo cáo khóa học: Three cyclin-dependent kinases preferentially phosphorylate different parts of the C-terminal domain of the large subunit of RNA polymerase II potx
Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx
... constitutes the second largest family of cyto-plasmic tyrosine kinases. In 1993, loss -of- function mutations in the BTKgene were reported as the cause of X-linked agammaglobulinemia. Of all the existing ... of all mutations in the BTK gene are missenseand some of these reduce the stability of the protein.This is exemplified by mutations in the BTK motif of the Tec homology (TH) domain [18]. This ... Conse-quently, the PH–TH domain doublet of ITK fusesdirectly with the linker B kinase region of SYK. The PH domain of TFKs usually binds to phosphatidylino-sitol-3,4,5-trisphosphate, thereby bringing them...
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Tài liệu Báo cáo khoa học: Three-dimensional structures of thermophilic b-1,4-xylanases from Chaetomium thermophilum and Nonomuraea flexuosa Comparison of twelve xylanases in relation to their thermal stability pdf
... However, the extension of the N-terminus of TRX II has been reportedto increase the thermostability [57]. The third region witheffect on the thermotolerance seems to be the Ser/Thrsurface. The ... some of the trends in the amino acid frequenciescould be related to the thermostability of xylanases.There was found an increased occurrence of arginines in the thermophilic xylanases. Large- scale ... xylanase II [39]. These results showed that the introduction of fivearginines into the Ser/Thr surface increased considerably the thermotolerance in the presence of the substrate.Another trend...
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Tài liệu Báo cáo khoa học: "Three BioNLP Tools Powered by a Biological Lexicon" doc
... of the BioLexicon, in order to illustrate the utility of the lexicon within the biomedical NLP field. The three applications are: • BLTagger: a dictionary-based POS tagger based on the ... • bigram of adjacent POS • bigram of adjacent BIOMED • bigram of adjacent POS-BIOMED During the construction of the trellis, white space is considered as the delimiter unless otherwise ... biomedical domain. To further tune Enju to the biology domain, (especially molecular biology), we have modified Enju to parse sentences based on the output of the BLTagger. As the BioLexicon...
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Báo cáo khoa học: Three-step hydroxylation of vitamin D3 by a genetically engineered CYP105A1 doc
... describe the identifica-tion of the novel metabolites, and the mechanism of a three- step hydroxylation by the R73V ⁄ R84A variant.In addition, we evaluated the biological significance of the recombinant ... stability of the oxygenated forms of the wild-type CYP105A1 and itsvariants.Figure 8 shows spectral analysis of the NADPH-dependent reduction of heme iron of the P450s.Although the wild-type ... system of Amycola-ta autotrophica, which is one of the successful applica-tions of the P450 enzymatic reaction, on an industrialscale [8]. The primary structure of the cloned genereveals that the...
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Báo cáo khoa học: Three novel carp CXC chemokines are expressed early in ontogeny and at nonimmune sites ppt
... arguably the most pleiotropic CXC chemokine. But the key to the conservation of CXCL12 is not so much the myriad of functions it is involved in, but in the critical importance of some of these functions ... in case of the deletion of one receptor, allows the other to take over the majority of its functions. The fact that fish haveduplicate genes for both CXCL12 and CXCR4 is a likelyresult of a genome ... at the ÔDe Haar Vis senÕfacility in Wageningen. Fish were fed dry food pellets(Provimi, Rotterdam, the Netherlands) at a daily ration of 0.7% of their estimated body weight. R3xR8 are the offspring...
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Báo cáo khoa học: "Veterinary decision making in relation to metritis - a qualitative approach to understand the background for variation and bias in veterinary medical records"
... category of motivation, but they might have been more or lessfocussed on each of the three levels/categories of motiva-tion.At the level of the individual cow, the veterinariansseemed to base their ... the collection of the data in and of itself as the basis for taking relevant actionat the farm. They may skip the process of systematic anal-ysis of data and give advice based on their immediate ... adjusting of the score to fit to the treatment decision. This category of veterinarians based the treatment decision on an overallevaluation of the case, irrespective of the existence of scores.5)...
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Tài liệu Báo cáo khoa học: Aldehydes release zinc from proteins. A pathway from oxidative stress⁄lipid peroxidation to cellular functions of zinc pptx
... MT protect the liver and the heartagainst the toxic effects of ethanol [45–47]. The aboveresults suggest that a critical aspect of the protectivefunction of MT is the scavenging of the acetaldehydeformed ... none of the aldehydes affects the absorbance of PAR. The data for the reaction of MT with formalde-hyde were corrected for the absorbance changes in the absence of MT.Thiol reactivities of MT ... transcription of the apoprotein thionein, which also reacts with alde-hydes. Indeed, addition of a hexapeptide that contains three of the 20 cysteines of thionein suppresses the for-mation of protein–hydroxynonenal...
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Tài liệu Báo cáo khoa học: Hu-K4 is a ubiquitously expressed type 2 transmembrane protein associated with the endoplasmic reticulum ppt
... Exon–intron structure of the Hu-K4 gene. (A) Position of the exons on the BAC clone CTC-492K19 (GenBank AC010271.8). The firstand the last nucleotide of each exon are given. The positions of the polyadenylation ... site, the stop codon and the putative start codons ATG1and ATG4are indicated. The size of exons 1–5 is drawn in scale. (B) Alternative splicing of the 5¢-UTR. The splice variants, the number of nucleotides ... not reveal any alternativesplicing in the ORF or in the 3¢ untranslated region(UTR). To explain the splice variants observed in the Northern blot we analysed the 5¢-UTR of the availableseveral...
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Tài liệu Báo cáo khoa học: A second novel dye-linked L-proline dehydrogenase complex is present in the hyperthermophilic archaeon Pyrococcus horikoshii OT-3 pptx
... subunit of PDH2 and the a subunit of the T. profundus enzyme, respectively (Fig. 3), while the b1 subunit showed 56% and 64% sequence identitieswith the b2 subunit of PDH2 and the b subunit of the T. ... show the amino-acidalignment of the a and b subunits of PDH1, PDH2 andT. profundus dye-l-proDH. The amino-acid sequence of the a1 subunit of PDH1 showed 31% and 32% identi-ties with the a2 subunit ... analyses of the prosthetic groups. Elution profiles of extracts of recombinant PDH1 (A), the b subunit of PDH1 (B), the a subunit of PDH1(C), native PDH1 prepared from P. horikoshii cells(D), and the...
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Báo cáo khoa học: How a lipid mediates tumour suppression Delivered on 29 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden pdf
... used to predict the outcome of disease, and to guide the choice of thera-peutic regimens.Fig. 3. Alternative tumour suppressormechanisms of PI3K-III. Three alternative(hypothetic) tumour suppressor ... ESCRT-III is recruited, cargo is deubiquitinat-ed by deubiquitinating enzymes recruited by ESCRT-III[61], and ESCRT-III serves to sever the neck of the forming invagination, thereby securing the ... known about the specific functions of the various PI3K-III subunits in autophagy. However,recent evidence suggests that the specific function of ATG14 in autophagy may reflect the ability of thisprotein...
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Từ khóa: báo cáo khoa học mẫubáo cáo khoa học y họcbáo cáo khoa học sinh họcbáo cáo khoa học nông nghiệpbáo cáo khoa học lâm nghiệpbáo cáo khoa học thủy sảnchuyên đề điện xoay chiều theo dạngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Nghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Thơ nôm tứ tuyệt trào phúng hồ xuân hươngBT Tieng anh 6 UNIT 2Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015MÔN TRUYỀN THÔNG MARKETING TÍCH HỢP