Báo cáo khoa học: Functional interplay between viral and cellular SR proteins in control of post-transcriptional gene regulation pptx
Báo cáo khoa học: Functional interplay between viral and cellular SR proteins in control of post-transcriptional gene regulation pptx
... environments.The interplay between viral and cellular SR proteins certainly has a substantial effect on post-Table 1. Functional interplay between viral proteins and cellular SR proteins as well as SR kinases ... proteins SR PABCFig. 2. Viral and host gene expression is modulated through the interplay between viral proteins and cellular SR proteins. (A) Viral SR proteins (rectangle) recruit cellular SR proteins (oval) ... Therefore, SR proteins, together with other RNA-binding proteins, coordinatethe coupling of splicing and polyadenylation. SR proteins participate in viral protein translation SR proteins are primarily...
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Báo cáo khoa học: Functional similarities between the small heat shock proteins Mycobacterium tuberculosis HSP 16.3 and human aB-crystallin docx
... the effect of ATP onsHsps using bovine a-crystallin to stabilize partially dena-turedproteinsduringreactivationinanATP-dependentmanner [24] and indicating the involvement of ATP in substrate ... teinexpression for the pET 16b-MTB HSP 16.3 vector at time point zero, 3 and 6 h after 2 h of induction and post heat shock. (C) SDS/PAGE of cells containing aB-crystallin induced and not induced ... tw o proteins. The conservedcore a-crystallin domain observed in proteins of the sHsp spans resi-dues of E67–I161 in the aB- crystallin sequence.Fig. 5. The chymotrypsin proteolysis of MTB...
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Tài liệu Báo cáo khoa học: Functional interaction between RNA helicase II⁄Gua and ribosomal protein L4 pptx
... activity and GTP-stimu-lated RNA foldase activity [17–19]. The presence of both RNA unwinding and RNA folding activities in two distinct domains of the same protein highly sug-gests a role of Gua in ... is a multifunctional nucleolar protein involved in ribosomal RNA processing in Xenopus laevis oocytes and mammalian cells.Downregulation of Gua using small interfering RNA (siRNA) in HeLacells ... respectively. Thegrowth of yeast cells containing both Gua and RPL4 in a triple drop-out medium that lacks tryptophan,leucine, and histidine indicates interaction of the two proteins (Fig. 1B, right)....
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Báo cáo khoa học: "The Tradeoffs Between Open and Traditional Relation Extraction" potx
... one of the following labels: B-REL,indicating the start of a relation, I-REL, indicatingthe continuation of a predicted relation, or O, indi-cating the token is not believed to be part of an ... set of relational tuples withoutrequiring any relation-specific human input. OpenIE’s extraction process is linear in the number of documents in the corpus, and constant in the num-ber of relations. ... learned in an unsupervised man-ner. Klein and Manning analyze the tradeoffs be-28tween the two approaches to parsing and argue thatstate -of- the-art parsing will benefit from employingboth...
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Báo cáo khoa học: Direct interaction between CD91 and C1q docx
... calreticulininhibition indicates that only a part of the binding siteson C1q is shared between CD91 and calreticulin. Nobinding was detected between CD91 and calreticulin in the ELISA, regardless of ... more of these ligand-binding clusters. Someinhibition was also observed with the CD91 ligandsa-2-macroglobulin and exotoxin A. These ligandsoccupy the CD91 ligand-binding cluster II and IV,thereby ... distinct binding between calreticulin and CD91 and Walters and Berwin [47]reported that the uptake of calreticulin is differentfrom another CD91 ligand, thereby suggesting thatcalreticulin...
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Báo cáo khoa học: "A Tradeoff between Compositionality and Complexity in the Semantics of Dimensional Adjectives" potx
... properties of this kind of reasoning are dependent on the types of relations that appear in the knowledge base. Thus in the present paper, I investigate the kinds of relations that appear in formal ... completeness, termination and time complexity of the algorithm depends on what kinds of relations appear as constraints in the system, and on the order in which constraints are taken off the queue. ... by hand, but some of them, especially those with commonsense domains involving spatial and temporal knowledge, are amenable to interaction by means of a natural language interface. Linguistic...
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Tài liệu Báo cáo khoa học: How to remain nonfolded and pliable: the linkers in modular a-amylases as a case study ppt
... angles between the participatingTable 1. Amino acid frequencies (%) in a-amylase linkers, in a set of globular proteins, in the Swiss-Prot databank and in intrinsicallyunstructured proteins. Aminoacid ... the ring may sterically disfavor extensivebending in this region, which could result in unwantedinteractions between the linker and the binding module. In this respect, 72% of the C-terminal ... structure of this domain in recently available sequence and genomedatabanks. Interestingly, this domain was found in some closely related bacterial species, but mainly in nonvertebrate animals, and invariably...
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Tài liệu Báo cáo khoa học: A novel c-N-methylaminobutyrate demethylating oxidase involved in catabolism of the tobacco alkaloid nicotine by Arthrobacter nicotinovorans pAO1 ppt
... Thesimilarity of the C-terminal domain of MABO to other proteins of the sarcosine dehydrogen ase and oxidase familymay indicate that this is the site of attachment of tetra-hydrofolate to the ... covalently attachedflavin, synthesized only in bacteria grown in the presence of nicotineThe DNA carrying the sarcosine dehydrogenase-likeORF63, corresponding to a protein of 813 amino acidswith a ... blotting of extracts of Arthrobacter nicotinovorans pAO1 grow n in the presence(lane 1) and in the absence (lane 2) of nicotine, as described in theExperimental procedures. Lane 3, 1 lg of purified...
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Tài liệu Báo cáo khoa học: FGF-2, IL-1b and TGF-b regulate fibroblast expression of S100A8 doc
... the S100 family of Ca2+-binding proteins and are now accepted as markers of in ammation. They areexpressed by keratinocytes and in ammatory cells in human ⁄ murine wounds and by appropriately ... cells and keratinocytes in vitro. In this study, regulation and expression of S100A8 and S100A9 were examined in fibroblasts. Endotoxin (LPS), interferon c(IFNc), tumour-necrosis factor (TNF) and ... accumulation of ECM, in some forms of cataract[60]. The pattern of S100A8 gene regulation indicatesthat this protein may be involved in fibroblast-to-myo-fibroblast differentiation at sites of in ammation...
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Tài liệu Báo cáo khoa học: "Word Alignment for Languages with Scarce Resources Using Bilingual Corpora of Other Language Pairs" pptx
... performance of Chinese-Japanese word alignment, we build an interpolated model by interpolating the induced model and the original model. Generally, we can interpolate the induced model and the ... models. In order to obtain fine-grained interpolation models, we in- terpolate the three kinds of parameters using dif-ferent weights, which are obtained in the same way as described in Wu et ... probability is independent of the position of the Chinese word and the length of the Chinese sentence. And we assume that the position probability is in- dependent of the length of Japanese sentence....
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