Báo cáo khoa học: Kinetic hybrid models composed of mechanistic and simpliﬁed enzymatic rate laws – a promising method for speeding up the kinetic modelling of complex metabolic networks pptx

... used for the analysis of stability. Enzymatic rate laws and otherdetails of the full kinetic model are given in App-endix S1.Comparing simpliﬁed and mechanistic rate equations for individual ... designates the type of load parameter varied and the range of variation relative to the normalvalue of the reference state. The last four columns show the percentage of the total variation range of the ... rate laws approximate the kinetics of G6PD (see Table 2): the approximate models based on PL-, MM- and MA-type rate equations provided a reasonably good reproduc-tion of the exact load characteristics,...

Báo cáo khoa học: "Maximum Expected BLEU Training of Phrase and Lexicon Translation Models" pptx

... a reference translation. Therefore, instead of pushing the parameter update towards the reference translation (a. k .a. bold updating), the author proposed a local updating strategy where the ... as the objective, and train the models on a large parallel dataset. For training, we derive growth transformations for phrase and lexicon translation probabilities to iteratively improve the ... open-domain spoken language translation task show that the proposed method leads to significant translation performance improvement over a state -of- the- art baseline, and the system using the...

Tài liệu Báo cáo khoa học: "Cross-Domain Co-Extraction of Sentiment and Topic Lexicons" pdf

... requiressome annotated words in the target domain. In thispaper, we do not assume any predeﬁned rules and labeled data be available in the target domain.2.2 Domain AdaptationDomain adaptation aims at ... CRF algorithm proposed by (Jakob and Gurevych, 2010).TrAdaBoost We apply TrAdaBoost (Dai et al.,2007) on the source domain labeled data and the generated seeds in the target domain to train a ... the adaptive bootstrapping method and the RAP method perform much better than other meth-ods in terms of F-score. The reason is that part of the source domain labeled data may be useful for learning...

Báo cáo khoa học: "Bilingual Hebrew-English Generation of Possessives and Partitives: Raising the Input Abstraction Level" pptx

... addition to these pragmatic factors and as is the case for the English genitive, the construct state can realize a wide variety of semantic relations (Dahan-Netzer and Elhadad, 1998b), (Azar, ... mination of the default value of the definite feature remain difficult and vary a lot be- tween the two languages. This case study has demonstrated that the methodology of contrastive analysis of ... in an NP and it remains attached closest to the head. In (Dahan-Netzer, 1997) and (Dahan- Netzer and Elhadad, 199 8a) , we have refined the D/Q classification and preferred using functional...

Báo cáo khoa học: Tyrosine-dependent basolateral targeting of human connexin43–eYFP in Madin–Darby canine kidney cells can be disrupted by the oculodentodigital dysplasia mutation L90V ppt

... sur-face biotinylation on the apical and basolateral surfaces and western blot analysis using the Cx43 antibody inorder to visualize the apical ⁄ basolateral distribution of Cx43–eYFP. This analysis ... cross the monolayer via the paracellular pathway, thus the accumulation of dye on the basolateral side represents paracellular ﬂux. Accumulation of the dye was determined by taking 25 lL aliquots ... directed to the basolateral surface. From our data, itremains unclear by what mechanism gap junctionalplaques are retained at the basolateral surface.We found that the ODDD-associated L90V mutantdisrupts...

Báo cáo khoa học: "Combining POMDPs trained with User Simulations and Rule-based Dialogue Management in a Spoken Dialogue System" docx

... after each user utterance and the reranking of the action set. At the end of each dialogue ses-sion, the reward and the policy updates are shown,i.e. new or updated state entries and action val-ues. ... exploration/exploitation trade-off inreinforcement learning The RL-DM maintains a policy, an internal datastructure that keeps track of the values (accumu-lated rewards) of past state-action pairs. The goal of ... candidate se-mantic parses using the semantics of a domain on-tology and the output of ASR. The visualization of the internal representation of the POMDP-DM includes the N best dialoguestates after...

Báo cáo khoa học: "Beyond Projectivity: Multilingual Evaluation of Constraints and Measures on Non-Projective Structures" doc

... provides anaccurate and at the same time expressivemeans for capturing non-projective struc-tures in natural language.1 IntroductionDependency analysis of natural language has beengaining an ever ... syntax, but only converted to a uniﬁeddependency format from other representations). The CoNLL data format is a simple tabular for- mat for capturing dependency analyses of naturallanguage ... structures. The interested reader can ﬁnd a more in-depth and broader-coverage discussion of properties of depen-dency trees and their application to natural languagesyntax in (Havelka, 200 7a) .As future...

Báo cáo khoa học: Vibrio cholerae hemolysin Implication of amphiphilicity and lipid-induced conformational change for its pore-forming activity ppt

... monitored accumulation of the toxin at the interface of water and chloroform. The ratio of the aqueous phase concentration of the HlyA followingpartitioning with chloroform, c to the initial value, ... a nonionic detergent that forms a single phasemixture with water at 4 °C and separates into a water-rich and detergent-rich phase at 23 °C [20], and (b) by using the interface of water and a ... choleraehemolysinImplication of amphiphilicity and lipid-induced conformational change for its pore-forming activityKausik Chattopadhyay1, Debasish Bhattacharyya2 and Kalyan K. Banerjee11National...

Tài liệu Báo cáo khoa học: Suppressed catalytic efﬁciency of plasmin in the presence of long-chain fatty acids Identiﬁcation of kinetic parameters from continuous enzymatic assay with Monte Carlo simulation ppt

... of plasmin and sub-strate, the initial reaction rate cannot be approximatedreliably with a linear function, and the differential rate equation of the classic Michaelis–Menten frameworkcannot ... The ‘0 ’ indicates the set of parameters in the absence of fatty acids. Shaded ellipses combine parametersbelonging to the same type of fatty acid (data for oleate and the absence of fatty acids ... its natural substrates.Materials and methodsMaterialsSodium salt and free acid forms of oleic, stearic and arachi-donic acids were purchased from Sigma-Aldrich Kft (Buda-pest, Hungary) and...

Báo cáo khoa học: "Conﬁdence-Weighted Learning of Factored Discriminative Language Models" pptx

... represent each token by multiple factors – such as part -of- speech, lemma and surface form– and capture linguistic patterns in the target languageat the appropriate level of abstraction. Instead of estimating ... highly overlapping and correlated factoredfeatures, and extend a robust learning algorithm tohandle them and cope with a high rate of label noise. For discriminatively learning language models, we ... standard Matrax features for re-ranking.Finally, we measure the quality of the translationsre-ranked to the top.In order to obtain the required factors for the target-side tokens, we ran the...

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