... all-alpha domain, STATprotein DNA-binding domain and SH2 domain of stat6, and the zinc-finger domain, leucine-zipperdomain and fork-head domain of foxp3. In addition,for stat6 and foxp3, there were ... adjacent DNA-binding sites,a coiled-coil STAT protein all-alpha domain, which isimplicated in other protein–protein interactions, aSTAT protein DNA-binding domain and an SH2domain, which binds phosphorylated ... the inducible chain of the IL-12 receptor (IL-12Rb2).Binding of IL-12 to its receptor induces signallingthrough STAT4, which further enhances IFN-c pro-duction and induces the expression of...