... Development of an HSV-tk transgenic mouse modelfor study of liver damageYan Zhang, Shu-Zhen Huang, Shu Wang and Yi-Tao ZengShanghai Institute of Medical Genetics, Shanghai Children’s ... Institute of Switzerland, Basel, Switzerland) for pTK-neo plasmid,polyclonal rabbit anti-(HSV-tk), Hep-G2 and HC-11cell lines, respectively. We would like to thank DrsZhao-Rui Ren, Jing-Zhi Zhang ... shown).Fig. 3. RT-PCR of HSV-tk expression in the transgenic mouse TK 5- F 1-4 55. M, 100-bp marker; 1, positive control (Hep-G2 cells trans-fected with plasmid of pCMV-TK); 2, negative control (Hep-G2cells);...