Báo cáo khoa học: Enzymes in organic media Forms, functions and applications potx

... ARTICLE Enzymes in organic media Forms, functions and applications Munishwar N. Gupta and Ipsita RoyChemistry Department, Indian Institute of Technology, Delhi, Hauz Khas, New Delhi, IndiaEnzyme ... medium engineering [13], solvent freesystems and eutectic mixtures [1,3,14], smart biocatalysts in organic media [15], and bioanalysis and biosensors in organic media [2–5].Forms and formulationsWhile ... that enzymes are not stable in neat organic solvents. Unfortunately, a clear distinction between expo-sure to organic media and working in such media has notbeen made by many workers. When enzymes...

Báo cáo khoa học: LRRK2 in Parkinson’s disease: genetic and clinical studies from patients ppt

... WD40domain. Because WD40 domain is involved in mediat-ing protein–protein interactions, the LRRK2 G2385Rvariant may impact on interactions with substrates and ⁄ or regulatory proteins. Preliminary ... multidomain protein comprising (fromN-terminal to C-terminal), armadillo (ARM), ankryn(ANK), LRR, Ras of complex proteins (ROC), C-ter-minal of ROC (COR), mitogen-activated proteinkinase kinase kinase ... fromEuropean and US origin and for 1–3% of sporadicPD from most Caucasian populations. This mutationis located in the kinase domain of the protein and maybe associated with increased kinase activity...

Báo cáo khoa học: Acetylcholinesterase in cell adhesion, neurite growth and network formation pot

... binding partner, speciﬁcally the globulardomain IV of the b1 chain of laminin [23]. In vitrobinding studies similarly indicated binding of acetyl-cholinesterase to laminin-1 [24], which was inhibitedby ... site inhibitors (fasciculin, propi-dium and gallamine) and an anti-acetylcholinester-ase mAb. Increasing the ionic strength, or decreasingthe pH decreased this binding [23,24], indicating adominant ... ofacetylcholinesterase, for example, protein–protein interactions. Recent ﬁnd-ings have revealed that laminin-1 is an interaction partner for acetylcholin-esterase. The binding of acetylcholinesterase...

Báo cáo khoa học: AKAP12 in astrocytes induces barrier functions in human endothelial cells through protein kinase Cf pptx

... scaffold protein, and has been shown toassociate with protein kinase C (PKC), protein kina-se A, calmodulin, cyclins, F-actin, and b-adrenergicreceptors [11–13]. Thus, AKAP12 functions as adynamic ... and migration [7,30,31]. These data showthat AKAP12 plays a critical role in mediating impor-tant interactions between retinal endothelial cells and astrocytes during retinal angiogenesis and ... movement and differentiation in developing retina. Brain Res DevBrain Res 118, 135–145.3 Stone J, Itin A, Alon T, Pe’er J, Gnessin H, Chan-LingT & Keshet E (1995) Development of retinal vascula-ture...

Báo cáo khoa học: "COPYING IN NATURAL LANGUAGES, CONTEXT-FREENESS, AND QUEUE GRAMMARS" potx

... grammar modulo the terminal vocabulary and the rules which insert terminals. Another way of stating this is that the lexicon of Indonesian is finite but of an indefinite size (what Gurevich ... copying constructions which, while productive, cannot be easily shown to apply to infinite sublanguages. To allow such finite copying constructions to be taken into account in formal modeling, ... formal languages with indefinite terminal vocabularies, is intended in the same spirit. The allure of identifying formal language theoretic cor~cepts with linguistic ones in the simplest possible...

Báo cáo khoa học: " a Movie Dialogue Corpus for Research and Development" potx

... created and how it is structured are pro-vided along with its main statistics and cha-racteristics. 1 Introduction Data driven applications have proliferated in Com-putational Linguistics during ... are: information retrieval (Qin et al., 2008), machine translation (Brown et al., 1993), question answering (Molla-Aliod and Vicedo, 2010) and dialogue systems (Rieser and Lemon, 2011). In ... The extracted information was finally organized in dialogical units, in which the information regar-ding turn sequences inside each dialogue, as well as dialogue sequences within each movie...

Báo cáo khoa học: "Semantic Role Labeling via FrameNet, VerbNet and PropBank" potx

... contains the number of training and testing in- stances and each of the other rows contains theperformance obtained for different feature com-binations. The results are reported for the label-ing ... on FN, we trained our clas-siﬁer on 46,734 training instances and tested on11,650 testing instances, obtaining an accuracy of91.11%. For ILC detection the results are depicted in Table 4. The ... for the uniﬁed usage of FN, VN and PB, ex-plaining why and how it is possible to link them.3 Linking FrameNet to VerbNet and PropBank In general, predicates belonging to the same FNframe have...

Báo cáo khoa học: "Dependency Parsing of Hungarian: Baseline Results and Challenges" potx

... using cascaded chunking. In Proceedings of the 6th Conference on Natural Lan-guage Learning - Volume 20, COLING-02, pages1–7.Ryan McDonald and Joakim Nivre. 2011. Analyzing and integrating ... extending the training dataset without-of-domain parses is not convincing. In spiteof the ten times bigger training datasets, thereare two subcorpora where they just harmed theparser, and the ... struc-turale. Klincksieck, Paris.64Kristina Toutanova, Dan Klein, Christopher D. Man-ning, and Yoram Singer. 2003. Feature-rich part-of-speech tagging with a cyclic dependency net-work. In Proceedings...

Tài liệu Báo cáo khoa học: Enzymes for the NADPH-dependent reduction of dihydroxyacetone and D-glyceraldehyde and L-glyceraldehyde in the mould Hypocrea jecorina doc

... tagged protein had a similar activity in crude yeastextract as the untagged protein, indicating that the tagwas not interfering with the protein activity. Thetagged protein was puriﬁed and then ... histidines tothe end of the open reading frame, and then expressed in S. cerevisiae. The tagged protein had a similar activ-ity in the crude extract as the nontagged protein, indi-cating that ... dehydrogenases in mould. The previouslypuriﬁed enzymes showed activity with glycerol and NADP in the oxidizing direction and activities withDHA or d-glyceraldehyde and NADPH in the redu-cing direction....

Báo cáo khoa học: Enzymes of creatine biosynthesis, arginine and methionine metabolism in normal and malignant cells Soumen Bera1, Theo Wallimann2, Subhankar Ray1 and Manju Ray1 potx

... thecytosolic enzymes, arginase I and ODC direct ornithinetowards polyamine synthesis and the mitochondrial enzymes arginase II and ornithine aminotransferasefavor the channeling of ornithine to proline ... respective enzymes in tumor cell metabolism. Against this back-ground, we studied creatine synthesizing enzymes, AGAT and GAMT, as well as CT-1 and actual creatinetransport. The enzymes intimately linked ... signiﬁcant increase in theenzymatic activity and protein expression of bothAGAT and GAMT in sarcoma and in two othermalignant cell lines compared to the levels of thesetwo creatine synthesizing enzymes...

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