Báo cáo khoa học: The subcellular organization of strictosidine biosynthesis in Catharanthus roseus epidermis highlights several trans-tonoplast translocations of intermediate metabolites docx
Báo cáo khoa học: The subcellular organization of strictosidine biosynthesis in Catharanthus roseus epidermis highlights several trans-tonoplast translocations of intermediate metabolites docx
... ª 2011 FEBS 763 The subcellular organization of strictosidine biosynthesis in Catharanthus roseus epidermis highlights several trans-tonoplast translocations of intermediate metabolites Gre´gory ... homo-oligomer in vivoTo complete the characterization of the subcellular organization of the epidermis- located steps of MIA biosynthesis, we analyzed the subcellular localization of TDC using the transient ... organiza-tion and possible protein interaction of TDC, LAMTand SLS, comprising the three enzymatic steps preced-ing the biosynthesis of the first MIA strictosidine within the epidermis. This led us to...
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Báo cáo khoa học: The subcellular localization of vaccinia-related kinase-2 (VRK2) isoforms determines their different effect on p53 stability in tumour cell lines pdf
... role in controlling the binding specificity of the N-terminal transactivation domain of p53. Indeed, the p53 phosphorylated by VRK2B shows a reduction in ubiquitination by Mdm2 and an increase in ... determined by their subcellular localization and the proteins present in the corresponding compartment,and by their C-terminal domain, which mediates inter-actions with different proteins. Their ... the signalling pathway to which these kinases belong. Forinstance, VRK2B and VRK1 are localized in the nucleus but differ in their last 90 amino acids in the C-terminus.Stabilization of p53 is part of...
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Tài liệu Báo cáo khoa học: "The Effect of Corpus Size in Combining Supervised and Unsupervised Training for Disambiguation" pdf
... that the combined sys-tem only improves the performance of the parser f or small training sets. Sur-prisingly, the size of the unannotatedcorpus has little effect due to the noisi-ness of the ... (without Collins) are given in the first lines. #is the size of the test set. The baselines are 73.1% (RC) and 51.4% (PP). The combined methodperforms better for sm all training sets. There is no ... One of its vari-ants computes the estimate in question as the average of three b ackoffs. In addition to the maximum used here, testing other combina-tion strategies for the MI values in the...
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Báo cáo khoa học: "The clinical value of daily routine chest radiographs in a mixed medical–surgical intensive care unit is low"
... endotra-cheal tubes, intravenous lines and chest drains, but not afterinsertion of nasogastric tubes. In addition, CXRs wereobtained in the case of worsening of oxygenation. As a rule, noroutine CXR was ... in case of unex-pected infiltrates on the CXR; repositioning of tubes in case of malposition of orotracheal tubes (ignoring planned extuba-tions); ultrasound of the thorax in case of pleural ... tubes(ignoring planned changes such as removal of intravenouslines). The observers were not involved in the daily care of the patients, and ICU physicians were not aware of this part of the observation....
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Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf
... confirmed by Lin-54 bind-ing to the CHR, cooperating with E2F4 binding to the CDE in EMSAs in vitro [86].ChIP experiments on the Cdc2 gene also providedinsights into the association of other cell ... proteinswith the promoter. E2F4 binding during the cell cyclecoincides with the binding of p107 or p130 [61,85].Another E2F site distal to the E2F ⁄ CDE acts as anactivating element binding ... -3. These acti-vating E2Fs cooperate with NF-Y proteins binding toCCAAT-boxes and with Myb proteins associating witha distal Myb site in activating the Cdc2 promoter.Binding of the activating...
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Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: intersubunit interactions during virus assembly doc
... of the precise residues and interac-tions involved in the NTD–CTD interface [46]. Most of these involve side chains from helix 8 of the CTDwhich pack against the N-terminal end of helix 4 of the ... of the NTD of a neighboring subunit in the hexamer.Additional contacts involve helix 11 of the CTD and the C-terminal end of helix 7 of the NTD of the neigh-boring subunit. The NTD–CTD interface, ... involved either in the assembly of the immatureHIV-1 capsid, or in the reassembly of CA into amature capsid. The detailed description of the structureand conformational dynamics of these interfaces,together...
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Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: designing inhibitors of capsid assembly ppt
... of both the CAI peptide and a-helix 9 of CTD during formation of the peptide–protein and protein–protein complexes.These NMR experiments also allowed the determina-tion of the CTD binding site. ... (allosteric) effect of CAI binding on the assem-bly of the immature capsid lattice, but a direct bindingeffect in the conserved CTD binding pocket duringmature assembly. On the other hand, mutations ... in red, the b-sheets in yellow and the loops in green. The circle at the bottom of the figureindicates the region where the binding of CAP-1 occurs. The figures were producedusingPYMOL (http://www.pymol.org)...
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Tài liệu Báo cáo khoa học: The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding pptx
... that the BMPR-IA binding site of the relatedBMP-7 largely coincides with the noggin-binding area[32,42]. Thus, the proBMP-2 binding to noggindetected here indirectly confirms the interaction of proBMP-2 ... to the ECD of BMPR-IA.Furthermore, the results indicate that both proteinsinteract with the same epitope on the ECD becauseproBMP-2 binding can be inhibited by BMP-2.To assess binding of ... proBMP-2 induced ectopic bone formation in rats, indicating that the pro-peptide does not signifi-cantly impair the bone-inducing activity of matureBMP-2 [8]. We are interested in the role of the...
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Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt
... upregulation in the liver of streptozotocin-induced diabetic rats and the suppres-sion of such elevation following insulin injection[21,22], we decided to investigate the effect of NHCH2CHCOOHNH2L-kynurenineCHOCOOHCOOHNH2Tryptophanα-amino-β-carboxymuconate-ε-semialdehyde ... numbers. The alternative conformations of the Trp–Met couple can beobserved; the arrows indicate the unidirectional movement of the two protein residues upon ligand binding. The dotted line highlights the ... b)8barrel domain is colored in light blue and the ACMSD-specific small insertion domain in blue. The DHAP molecule and the protein residues involved in metal coordination are shown assticks; the Zn2+ion...
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Tài liệu Báo cáo khoa học: The chitinolytic system of Lactococcus lactis ssp. lactis comprises a nonprocessive chitinase and a chitin-binding protein that promotes the degradation of a- and b-chitin doc
... polymorpha-chitin (antiparallel packing of the chitin chains);b-chitin (parallel packing of the chitin chains); and the minor polymorph c-chitin (mixture of parallel andantiparallel chain packing) [1,2]. ... show the general importance of chitin-binding proteins in chitin turnover, and provide the first example of a family 33 chitin-bindingprotein that increases chitinase efficiency towards a-chitin.AbbreviationsCBM, ... Residues involved in the chitin-binding andfunctional properties of CBP21 [10,17], but not conserved in LlCBP33A or ChbB, are shaded grey. The arrow indicates the terminal aminoacid of the N-terminal...
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Từ khóa: tài liệu báo cáo khoa học bản chất của khủng hoảng kinh tế thế giới pdflam the nao de tom tat bao cáo khoa hocbáo cáo khoa họcbáo cáo khoa học mẫubáo cáo khoa học y họcbáo cáo khoa học sinh họcNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Chuong 2 nhận dạng rui roGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMMÔN TRUYỀN THÔNG MARKETING TÍCH HỢP