... highsequence identity, Fig. 1, and many other residues displayconservative changes. The region between residues 54 and 79 of CR I – II, encompassing the linker, helix C and start of the second calcium-binding ... allowed us to analyze the biochemical and structural properties of CR I–II and tocompare them with Calb I–II. Our data show that CR I–II and Calb I –II share virtually the same EF-hand structures.However, ... the calcium-binding ligands are designated by their coordinates: x, y, z, -y, -x and -z [60]. Residues discussed in the text are given in bold (G34,K60 and G81 of CR I –II and G29, G66, R68, G71 and G74 of CalbI–II)....