Báo cáo khoa học: "Hybrid Methods for POS Guessing of Chinese Unknown Words" pot
Tài liệu Báo cáo khoa học: "Generalization Methods for In-Domain and Cross-Domain Opinion Holder Extraction" pdf
... includes the lexical form of the predicateis most likely a sparse feature. For the opinionholder me in (10), for example, it would corre-spond to A1 shock. Therefore, we introduce for each generalization ... In-Domain Evaluation of Learning-based Methods Table 7 shows the performance of the learning-based methods CRF and CK on an in-domainevaluation (ETHICS-domain) using differentamounts of labeled training ... F-score than RB.6.3 Out -of- Domain Evaluation of Learning-based Methods Table 9 presents the results of out -of- domain clas-sifiers. The complete ETHICS-dataset is used for training. Some properties...
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Tài liệu Báo cáo khoa học: Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat docx
... (Sigma)was performed as previously described [21]. However for easier hand ling of the cells, treatment was performed onHeLa cells instead of CHO K1 cells. C ells were thenincubated with of 5 lgámL)1Tat±GFP ... sterichindrance of the heterologous protein itself could reducethe exposure of these shorter peptides to cellular structures,and therefore, reduce the ef®ciency of translocation. For recombinant ... rightward shift of the s ignal was observedsignifying a reduction of the uptake of the Tat peptide atlow temperature. Likewise, a threefold r eduction of theuptake at 4 °C has been reported for the...
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Báo cáo khoa học: " A Tool for Error Analysis of Machine Translation Output" doc
... search for in the error typology, andthen search backwards or forwards for error annota-tions of that type. It is possible both to search for specific errors deep in the typology, and to search for ... tool for human annotations of bilingualmaterial. Its main purpose is error analysis for ma-chine translation. BLAST is designed for use in anyMT evaluation project. It is not tied to the informa-tion ... especially in combination with a part -of- speech analysis (Popovi´c et al., 2006).Human evaluation is also often quantitative, for instance in the form of estimates of values such asadequacy and...
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Báo cáo khoa học: GTP binding and hydrolysis kinetics of human septin 2 pot
... guaninenucleotides with a Kd of 0.28 lm for GTPcS and 1.75 lm for GDP. It hasa slow exchange rate of 7 · 10)5s)1 for GTPcS and 5 · 10)4s)1 for GDP,and an apparent kcatvalue of 2.7 · 10)4s)1, ... completion of most of the studies describedherein. Given the conserved nature of this residue we there-fore mutated the residue back to arginine and found thatnone of the properties of the protein ... nonphosphorylat-able S218A form of SEPT2 was examined, it had amuch higher Kdvalue of 2.5 lm for GTPcS and4.4 lm for GDP (Table 1). This was very similar tothe values obtained for SEPT2 produced...
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Báo cáo khoa học: "Medical treatment for the terminally ill: the ‘risk of unacceptable badness’"
... maintained comfortably for long enough,then a cure may eventually become possible.3. Surrogates dislike being in a position of making decisionsthat directly result in the death of a loved one. ... processes [2].An unintended side effect of modern technological advanceshas been the plausibility of maintaining moribund patients in astate of suspended animation for prolonged and sometimesindefinite ... options because of theirproximate knowledge of what the patient would have wantedbefore they became incompetent [7]. This position is basedon the postulate that any attempt to interject physicianpaternalism...
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Tài liệu Báo cáo khoa học: A strategy for discovery of cancer glyco-biomarkers in serum using newly developed technologies for glycoproteomics ppt
... previouslydemonstrated the application of this method to thedetermination of the glycan structure of a form of AFP [10]. However, identification of the details of aglycan structural change on a ... microarray system is the best tool for a ‘cell profiler’, and it is expected to be applicable for selection of cancer-specific lectins and for qualitycontrol of stem cells before transplantation [12–15].Recently, ... methylesteri-fication of sialic acid moieties. All spectra wereobtained in the positive ion mode using MALDI–quadrupole ion trap (QIT)-TOF MS.A strategy for discovery of cancerglyco-biomarkersOn the basis of...
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Tài liệu Báo cáo khoa học: Structural bases for recognition of Anp32⁄LANP proteins doc
... of PP2A-C protrudes out enough to fit well into the grooveformed by the concave surface of the LRR domain.Stabilizing interactions could form between His230 of PP2A-C and Asp119 and Asn94 of ... of theLRR domain only indirectly. By screening of a humanbrain cDNA library (Clonetech, Mountain View, CA,USA) for a total of approximately 5 million clones, wefound about 600 potential positives ... Phosphorylation of Ser158, which is immediately downstream of theLRR domain, could, for instance, induce a conforma-tional change of the adjacent region, which could berequired for Atx1 binding.Finally,...
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Tài liệu Báo cáo khoa học: Structural basis for cyclodextrin recognition by Thermoactinomyces vulgaris cyclo⁄maltodextrin-binding protein ppt
... (Fig. 5A). The positionsand the conformations of the three loops of EcoMBPare different from those of TvuCMBP. Trp62, locatedat region N-I, is found at the center of the curvedform of maltotetraose ... (Glc1–Glc4) of the round shape of c-CD bound to TvuCMBP. The conformations of Glc3 bound to TvuCMBP and the third glucose resi-due, Glc3¢, of maltotetraose bound to EcoMBP aresuperimposed well, ... architecture of the C-domain of Tli TMBP may be more s uitable for thespecific b inding to small oligosaccharides lik e trehalose.Comparison of the N-domain parts of thesugar-binding sites of TvuCMBP,...
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Tài liệu Báo cáo khoa học: Design, structure and biological activity of b-turn peptides of CD2 protein for inhibition of T-cell adhesion ppt
... constant of most of theamide protons was in the range of 6–8 Hz, suggestive of rapidly interconverting conformers that coexist in solution.The temperature coefficients of chemical shift of amidesGlu1 ... National University of Singapore for the use of computationalfacilities; Prof. Arthur J. Olson, the Scripps Research Institute , USA, for providing us with the AutoDock software. This research ... Ser4-Thr5-Asn6-Gly7 for conformations of peptide cVY.Appendix 3. Peptides cEL and cYT: CD58 docking resultsstarting from the potential binding sites out of 100 runs.Fig. S1. Amide region of 500 MHz...
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Tài liệu Báo cáo khoa học: Complex transcriptional and translational regulation of iPLA2c resulting in multiple gene products containing dual competing sites for mitochondrial or peroxisomal localization docx
... sequences) inisoforms that carry both signals. It is important to note t hatsynthesis of the 63 kDa isoform obligatorily is relegated tothe peroxisomal compartment by virtue of the absence of any N-terminal ... compartme nt(expression of the 63 kDa isoform which does not possess amitochondrial localization signal) or into the mitochondrialcompartment (by production of isoforms containing amitochondrial ... up-regulation of the iPLA2c 63 kDa isoform in adipose tissue of Zuckerobese rats [67]. These results suggest that iPLA2c biosyn-thesis is highly regulated in regard to specific isoformexpression...
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