... as shown in Fig. 7B.Binding of monophenols to resting met-tyrosinaseresults in the inactive dead-end complex, but binding of o-diphenols leads the enzyme to the oxy-tyrosinaseform, the active ... related to the presence or absence of a seventhhistidine, adjacent to the sixth histidine involved in copper binding. Preceding the sixth histidine(H3Baccording to the nomenclature used in [6]), ... that the most characteristic signatures in the sequences are present in both proteins, tyrosinases andcatechol oxidases; these include the six histidine resi-dues involved in the binding of a...