... cagC and cagf reached values analogous togenes important for bacterial survival and homeostasis,such as catalase, urease and NapA; by contrast, the transcript abundance of other cag genes appeared ... lymphoma [1–3]. CagA, a major anti-genic factor of the bacterium, is the main signature of the cagPAI-positive strains. Indeed, cagPAI confersH. pylori the capability to express and translocate the CagA ... protein rather than being a component of the T4SS apparatus. Finally, interaction studies indicatedthat CagI might interact with CagZ and CagG, andweak evidence of interaction with Cagb was alsoobserved...