Báo cáo khoa học: Trigger factor interacts with the signal peptide of nascent Tat substrates but does not play a critical role in Tat-mediated export pptx
Báo cáo khoa học: Trigger factor interacts with the signal peptide of nascent Tat substrates but does not play a critical role in Tat-mediated export pptx
... Trigger factor interacts with the signal peptide of nascent Tat substrates but does not play a critical role in Tat- mediated export Wouter S. P. Jong1, Corinne M. ten Hagen-Jongman1, ... pTorA/P2 [ 17] a s a template and the primersRRTorA-SacI-fw (5¢-GCGCGGAGCTCAAGAAGGAAGAAAAATAATGAAC-3¢, SacI site underlined) andTorA/Lep2-BamHI-rv (5¢-GCATGGATCCCGCGCGCTTGATGTAATC-3¢, BamHI site ... for the Tat machineryconsisting of the i ntegral membrane proteins TatA/E, TatBand TatC [11].Little is known about the molecular mechanism of targeting and export of Tat- dependent proteins. In...
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Báo cáo khoa học: Peroxin Pex21p interacts with the C-terminal noncatalytic domain of yeast seryl-tRNA synthetase and forms a specific ternary complex with tRNASer potx
... USAAccurate aminoacylation of tRNA by aminoacyl-tRNAsynthetases (aaRSs) is a crucial step in the faithfultranslation of mRNA. In addition to their fundamental role in translation, aaRSs are ... A freestanding proofreading domain is required for pro-tein synthesis quality control in Archaea. Proc NatlAcad Sci USA 101, 10260–10265.29 Dagkessamanskaia A, Martin-Yken H, Basmaji F, BrizaP & ... In yeast, the tRNA-binding protein Arc1p is associated with MetRS andGluRS [17,22,23], and enhances the binding affinity forcognate tRNAs. The association of an aaRS with a puta-tive metabolic...
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Tài liệu Báo cáo khoa học: Platelet factor 4 disrupts the intracellular signalling cascade induced by vascular endothelial growth factor by both KDR dependent and independent mechanisms ppt
... affectsRaf1 activity in HUVEC. Increases in cAMP levels and the activation of the cAMP-dependent protein kinase A (PKA) may be involved [44]. Indeed, P KA inhibits the MAP k inase pathway by blocking ... (PLCc), a s ubstrate of KDRkinase, i s then phosphorylated and activated, leading to the activation of p rotein kinase C (PKC), followed by the serine/threonine kinase, Raf1 and then the threonine/tyrosinekinase, ... proliferation b y an intracellular mechanism involving the modulation of R af1 activity. The i nhibition of the MAP kinase pathway by an intracellular mechanisminduced by PF-4 suggests that this...
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Tài liệu Báo cáo khoa học: Branched N-glycans regulate the biological functions of integrins and cadherins doc
... findings mayexplain why bisecting GlcNAc-containing N-glycansare abundant in the brain [65]. In fact, mice carryingan inactive GnT-III mutant have an atypical neurolog-ical phenotype [66]. The ... has a large extracellularregion, a single transmembrane domain, and a shortcytoplasmic tail (except for b4). The N-terminaldomains of the a- and b-subunits associate to form the integrin ... Noda K, Higashiyama S, IharaH, Matsuura N, Hayashi N, Kawata S, Matsuzawa Y& Taniguchi N (2001) The addition of bisecting N-acet-ylglucosamine residues to E-cadherin down-regulatesthe...
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Tài liệu Báo cáo khoa học: Rotary F1-ATPase Is the C-terminus of subunit c fixed or mobile? docx
... the coiled-coil region of c and the complete a- helical C-terminusas held within the top of (ab)3. The rotary axis z was alignedalong the main axis of the shaft. The ‘bearing’ included a total of 138 residues ... revealedthat rotation around the w Ramachandran angle w aspreferred over that around /. We calculated the potentialbarrier f or the rotation around w and / angles in the dipeptide Ala-Gly by ab ... 2).Molecular dynamics simulations of the rotary mobility of c within the ‘hydrophobic bearing’ at the top of a 3b3 The molecular model of the rotary part of c and the surrounding part of (ab)3was...
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Tài liệu Báo cáo khoa học: Unfolding and aggregation during the thermal denaturation of streptokinase pptx
... to the sum of a number of two-state transitions. In these fittings the heat capacity change, DCp,fortheunfolding of each domain was fixed by using the valuesobtained from the analysis of the ... from these equations using the following set of parameters: a linear heat capacity function for the nativestate, Cp(N); the enthalpies and the heat capacities of the unfolded state, DHUand ... It appears thenthat domain B is not correctly folded in the aggregatesbecause part of its sequence is involved in interactionsassociated with the formation of the aggregate.At mildly acidic...
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Báo cáo khoa học: Human telomeric G-quadruplex: The current status of telomeric G-quadruplexes as therapeutic targets in human cancer pdf
... anticancer activity in tumour xenograft models, which indicatethat the approach may be applicable to the treatment of a wide range of human cancers. This minireview summarizes the available data on thesecompounds ... p16INK 4a kinase and p53 pathways [32–35]which can be visualized by the appearance of charac-teristic DNA damage foci using an antibody to the damage response protein cH2AX [36], or by a signifi-cant ... number of assays. The mostimportant are: (a) high-affinity in vitro telomeric quad-ruplex binding, with a K a value of at least 106m)1; (b) a low level of binding to duplex DNA, with a K a valueat...
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Báo cáo khoa học: Transcript profiling during the early development of the maize brace root via Solexa sequencing pot
... profiling of early lateral root initiation. Proc Natl Acad Sci USA101, 5146–5151.22 Inukai Y, Sakamoto T, Ueguchi-Tanaka M, Shibata Y,Gomi K, Umemura I, Hasegawa Y, Ashikari M, Kit-ano H & ... construction and sequencingFor Solexa tag preparation and sequencing, 1 lg of totalRNA was incubated with oligo(dT) beads to capture the mRNA with a poly (A) tail. First- and second-strand cDNAwas synthesized ... shared betweenbrace root and lateral or adventitious root development, such as genes par-ticipating in cell wall degradation and synthesis, auxin transport and signal- ing, ethylene signaling,...
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Báo cáo khoa học: Odorant binding protein has the biochemical properties of a scavenger for 4-hydroxy-2-nonenal in mammalian nasal mucosa doc
... the 16-h incubations, in which at least 50% of residual lig-and-binding capacity was maintained at the highest[HNE] ⁄ [OBP] values. In the case of 20-min incuba-tions, HNE inactivation was even ... HNE andAMA are shown for porcine (C) and bovine (D) OBP. Protein samples were incubated with a fixed saturating amount of AMA and increasingHNE. Each point on the y-axis shows the concentration ... formation of HNE–OBP adducts after incubation with increasingamounts of the aldehyde, and a spectrophotometric ti-tration that allowed quantitative determination of the HNE reactive amino acids...
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Báo cáo khoa học: "TWO THEORIES FOR COMPUTING THE LOGICAL FORM OF MASS EXPRESSIONS" doc
... bottle of wine on the table or the 250ml in this glass. Note that these can again be abstract entities: but rather than potentially being abstract conventional kinds of wine, they can be abstract ... as Wine is wine (two readings, both analytic) Wine is a wine (false) All wine is wine (analytic) Claret is a wine (true) Cheap wine is a wine (false) *All wine is a wine (semantically anomalous) ... postulate that A larab has fur. The s-theory can do this without difficulty: lamb' is true of individual lambs and the meaning postulate says of each of them that they have fur. But the...
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Từ khóa: báo cáo khoa học mẫubáo cáo khoa học y họcbáo cáo khoa học sinh họcbáo cáo khoa học nông nghiệpbáo cáo khoa học lâm nghiệpbáo cáo khoa học thủy sảnchuyên đề điện xoay chiều theo dạngNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXchuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMMÔN TRUYỀN THÔNG MARKETING TÍCH HỢPTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ