... GuopingZhao1,4 and Qinghua Zhang1,2,41 National Engineering Center for Biochip at Shanghai, China2 State Key Laboratory of Medical Genomics and Shanghai Institute of Hematology, Ruijin Hospital, ... sarcosine dehy-drogenase (Sardh), a flavoenzyme involved in the oxida-tive degradation of choline to glycine in rat [22], wasupregulated.Transcriptome remodeling in group HG rat liver In group ... withretinoid X receptors to initiate the transcriptional regu-lation of target genes. Three subtypes of PPARs (a,b ⁄ d and c) and retinoid X receptors (a, b and c) havebeen identified, and the...