Báo cáo khoa học: Adenine, a hairpin ribozyme cofactor – high-pressure and competition studies potx

... the activity to abasic ribozyme variantslacking A3 8. Detailed analysis of the pH dependenceof hairpin ribozymes variants with covalent substitu-tions indicates that the optimal cleavage and ... [8] and lower eukaryotes, amphibians, prokaryotes, bacterio-phages, and viroids and satellite viruses that infectplants. A ribozyme also exists in hepatitis delta virus, a serious human pathogen ... respect,we produced two adenine-dependent hairpin ribozymes[adenine-dependent hairpin ribozyme 1 (ADHR1) and adenine-dependent hairpin ribozyme 2] that requireadenine as a catalytic cofactor for their...

Tài liệu Báo cáo khoa học: "TOWARDS A DICTIONARY SUPPORT ENVIRONMENT FOR REAL TIME PARSING" potx

... syntactic analysis of substantial fragments of natural language. These developments also demonstrate that if natural language processing systems are to be able to handle the grammatical and ... to domain knowledge already encoded in the knowledge base of a limited domain natural language application such as a database query system. Given a hand-coded hierarchical organization of ... especially on grammatical theory - for example, Generalised Phrase Structure Grammar' (GPSG) (Gazdar et al., In Press), Lexical Functional Grammar (LFG) (Kaplan & Bresnan, 1982) - and...

Báo cáo khoa học: Novel a-conotoxins from Conus spurius and the a-conotoxin EI share high-afﬁnity potentiation and low-afﬁnity inhibition of nicotinic acetylcholine receptors doc

... a 3b2AnIB GGCCSHPACAANNQDYC a a3b2>> a 7PnIA GCCSLPPCAANNPDYC a a3b2>> a 7PnIB GCCSLPPCALSNPDYC a a7> a 3b2EpI GCCSDPRCNMNNPDYC a a3b4, a 3b2; a 7AuIA ... neuronal nAChR, and toxin SrIB a probable antagonist of musclenAChR, we decided to test peptides SrIA and SrIB inbiological preparations separately expressing neuronal(central, a 4b2, and ganglionic, ... 631 7–6 326.27 Sharpe IA, Gehrmann J, Loughnan ML, Thomas L,Adams DA, Atkins A, Palant E, Craik DJ & Lewis RJ(2001) Two new classes of conopeptides inhibit the a1 -adrenoceptor and noradrenaline...

Báo cáo khoa học: "WHAT A TYPE OF INTERACTION IS IT TOBE HT" potx

... micro-pauses) can, and regularly do, have substantial sequential and interactional conse- quences. The character of the talk after them is regularly different, or is subject to different analysis, ... sequential organization. Nearly all the technological interventions I have heard about whether replacing an interactant, or inserted as a medium between interactants impacts on this aspect ... this area that of understanding and misunderstanding. It is the sequential (including temporal) organization of the talk which, in ordinary conversation, provides running evidence to participants...

Báo cáo khoa học: cGMP transport by vesicles from human and mouse erythrocytes potx

... ⁄ – ⁄ Abcc4 – ⁄ – ,Abcc4 – ⁄ – ⁄ Abcc5 – ⁄ – and Abcc4 – ⁄ – ⁄ Abcg2 – ⁄ – , were generatedby crossbreeding of the single-KO mice. Male and female Abcc1 – ⁄ – , Abcc4 – ⁄ – , Abcc5 – ⁄ – , Abcc1 ... – , Abcc1 ⁄ 4 – ⁄ – , Abcc4 – ⁄ – ⁄Abcc5 – ⁄ – , Abcg2 – ⁄ – and Abcc4 – ⁄ – ⁄ Abcg2 – ⁄ – mice and WTmice were of comparable genetic background (FVB ormixed Ola ⁄ B6 and FVB) and were killed ... examinepotential differences in substrate afﬁnity between human and murine variants of the ABCC ⁄ Abcc transporters.Experimental proceduresAnimalsAbcc4 – ⁄ – [20], Abcc1 – ⁄ – [36] and Abcg2 – ⁄ – [37]...

Báo cáo khoa học: "Task-oriented Evaluation of Syntactic Parsers and Their Representations" potx

... data in the target domain is available, asis the case with the GENIA Treebank (Kim et al.,2003) for biomedical papers, a parser can be re-trained to adapt to the target domain, and larger ac-curacy ... include dependency parsers (Mc-Donald and Pereira, 2006; Nivre and Nilsson, 2005;Sagae and Tsujii, 2007) and deep parsers (Kaplanet al., 2004; Clark and Curran, 2004; Miyao and Tsujii, 2008). ... Adriaans, 2006; Erkan et al., 2007; Sætre et al.,2007). PPI identiﬁcation is a reasonable task forparser evaluation, because it is a typical informationextraction (IE) application, and because...

Báo cáo khoa học: LRRK2 in Parkinson’s disease: genetic and clinical studies from patients ppt

... uncertainPARK14 PLA2G6 22q13.1 AR ⁄L-dopa responsive dystonia-parkinsonismAwaiting more dataPARK15 FBX07 22q12-q13 AR ⁄ parkinsonism–pyramidal syndromeAwaiting more dataAD, Autosomal dominant; ... from four generations. Two large families withautosomal-dominant late-onset parkinsonism, family A (German–Canadian) and family D (Western Nebraska)are also linked to this PARK8 locus. In 2004, ... [3 3–3 5]. In2005, Mata et al. [24,36] reported a G2835R variant a PD family from Taiwan and it was thought that itcould be a pathogenic mutation. However, Tan et al.[37] and Di Fonzo et al....

Báo cáo khoa học: "COPYING IN NATURAL LANGUAGES, CONTEXT-FREENESS, AND QUEUE GRAMMARS" potx

... additional arguments, such as Kac (to appear), Kac, Manaster-Ramer, and Rounds (to appear), and Manaster-Ramer (to appear a; to appear b) may appear to be no more than flogging of dead horses. ... pluralize by reduplication. Rounds, Manaster-Ramer, and Friedman (to appear) argue that facts like this mean that a natural language should not be modeled as a formal language but rather as a ... a) and Manaster- Ramer and Rounds (to appear). The classificatory capacity is the set of languages generated by the various subgrammars of a grammar, and if we are willing to assume that linguists...

Báo cáo khoa học: Adenine and adenosine salvage pathways in erythrocytes and the role of S-adenosylhomocysteine hydrolase A theoretical study using elementary ﬂux modes Stefan Schuster and Dimitar Kenanov ppt

... esaKGPmiCLGPTAPDAP6GDHesaLGPOGP6OC2URP5PDANHSG2GGSSHPDANSGxoHGRGSSP5RP5XP7SAGP3P6FP4EKTIT A IP5REP5uXKTIIAGP3GP2MGPPDAPT A PEPNEKPPDAPTARYPtxeRYPsn a rtRYPCALCALetxC A LtrasnHDLHDANDANNEDAIENPPRPTRPDAPMAPMIODAONIPMADACUNADACUNXPYHPPRPTRPGHP1RXPYHetxP5RMRPysPPRPnPT A PMAPTAKAPDAPD A PMApAKesaPNPPTAPDA a N+aN+kaelaNK+K+k a elKKaNaPT A seenarbmemMAStxeMAS2HHASodA-SHycTMYCH1HHASobiRoteK'3escAcYCHFPKHDP6LGXHartnsccAteM++Fig. ... notapply to such cells.In metabolic pathway analysis, usually a distinction ismade between internal and external metabolites. Internalmetabolites are intermediates that have to fulﬁl a balanceequation ... standard function-ality of SAHH (here denoted as SAHH1) and another10 pathways starting from adenosine (rather thanS-adenosylmethionine) and involving SAHH1 in thebackward direction and SAHH2...

Tài liệu Báo cáo khoa học: TMPRSS13, a type II transmembrane serine protease, is inhibited by hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor pdf

... Tsubouchi H, Naka D, Takahashi K,Okigaki M, Arakaki N, Nakayama H, Hirono S, Sakiy-ama O, Takahashi K et al. (1989) Molecular cloning and sequence analysis of cDNA for human hepatocytegrowth factor. ... Yokohama, Japan2 Advanced Medical Research Laboratory, Mitsubishi Tanabe Pharma Corporation, Kamoshida-cho, Aoba-ku, Yokohama, JapanIntroductionType II transmembrane serine proteases (TTSPs) arestructurally ... sets: 5¢-TCCCATCTGTAGCAGCAACT-3¢ and 5 ¢-GGATTTTCTGAATCGCACCT-3¢ forTMPRSS13 (34 cycles), and 5¢-ATGGAGGCTGCTTGGGCAACA-3¢ and 5¢-ACAGGCAGCCTCGTCGGAGG-3¢for HAI-1 (26 cycles). The GAPDH-speciﬁc...

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