... data from the Multi-Center Health Survey in the State of São Paulo (ISA-SP), 2001–2002 in four areas of the state of São Paulo, southeastern Brazil: the cities of Botucatu and Campinas; an ... Campinas; an area covering the cities of Itapecerica da Serra, Embu, and Taboão da Serra; and the district of Butantã in the city of São Paulo. The sample was obtained through two-stage stratifi ed ... For each domain in each study area a minimum sample size of 200 was esti-mated based on a prevalence of 0.5, an error of 0.10, an alpha error of 0.05 and a design effect of 2. Considering a...