... (F)consists of the conserved N-terminal domain that con-tains active-site residues and part of the C- terminaldomain. The structure of the N-terminal domain is conserved among species (E. coli, ... which is distinct from the corresponding structures in the N, T and G forms, inwhich Tris is not identified.In contrast to l-glutamate, Tris binding induces alesser degree of structural changes, ... Tris, and Tris analogues, such as Bistris ortricine, induce no such effect. Similar speci c activa-tions have also been observed in other proteins [24–30]. As shown in Fig. 8, Tris is identified...