Báo cáo khoa học: The N-terminal region of the bacterial DNA polymerase PolC features a pair of domains, both distantly related to domain V of the DNA polymerase III s subunit ppt
Báo cáo khoa học: The N-terminal region of the bacterial DNA polymerase PolC features a pair of domains, both distantly related to domain V of the DNA polymerase III s subunit ppt
... compilation ª 2011 FEBS The N-terminal region of the bacterial DNA polymerase PolC features a pair of domains, both distantly related to domain V of the DNA polymerase III s subunit Ke˛stutis Timinskas ... conserved modules. E. coli, similar to many other Gram-negative bacteria, possesses DnaEas its sole replicative polymerase. By contrast, Gram-positive bacteria such as B. subtilis have both PolC and ... revealed that the N-terminal region of the bacterial replicative polymer-ase PolC includes two structural domains: PolC- NIand PolC- NII. Both domains are distantly related to domain V of the DNA...
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Báo cáo khoa học: Translation initiation region dependency of translation initiation in Escherichia coli by IF1 and kasugamycin pdf
... pCMS71 plasmid[44] was replaced with some of the correspondingDR -A cuagcuaauaaauuaAGGAGGauuuaaauAUGAAAGCAAUUUUCGUAc DR-B cuagcuaauaaauuaAGGAGGauuuaaauAUGAGUGAAUCACAAGCCc DR-C cuagcuaauaaauuaAGGAGGauuuaaauAUGAAAAAGGAGUCGACUc ... ratioCVR40D/MG1655CVR69/MG1655MG1655 + ksg/MG1655pSS101 3A TIR cuagcuaauaaauuaAGGAGGauuuaaauAUGaaaccucuagagucgacu 2A TIR cggauaacaauuucacacAGGAaacagaccAUGgaauugcaacacgauaag Fig. 1. Protein expression ... sequence(4–10 bases) was used. As shown in Fig. 3A, the genevariants with a long SD sequence (6–10 bases) gaveincreased 3A ⁄ 2A values in the mutants, whereas a four base SD sequence gave very similar...
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Báo cáo khoa học: "You Can’t Beat Frequency (Unless You Use Linguistic Knowledge) – A Qualitative Evaluation of Association Measures for Collocation and Term Extraction" pot
... precluding the ap-pearance of alternative tokens in various token slotcombinations, which results in higher scores formore constrained candidates. All measures assign a score to the candidates and ... terminological resource for the biomedical domain. 3.3 The Association MeasuresWe examined both standard statistics-based andmore recent linguistically rooted association mea-sures against mere ... well1Obviously, this goal is similar to ranking documents ac-cording to their relevance for information retrieval.compared with various more sophisticated as-sociation measures (AMs such as t-test,...
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Báo cáo khoa học: "Trace Prediction and Recovery With Unlexicalized PCFGs and Slash Features" pptx
... p, SBAR/SBAR-CLR to b, S/ fin to sf, S/ ppres/gap to sg, S /to/ gap to st,other S nodes to so, VP/ppres to vg, VP/ppast to vn, VP/pas to vp, VP/inf to vi, and other VPs to vo. A verb with an NP and ... classes are ordered. If a string is matched by the regular expressions of more than one word class, then it is assigned to the first of these word classes. For each word class,we compute part -of- speech ... class [A- Za-z0-9-]+-old which con-tains the word 20-year-old, the class [a- z] [a- z]+ifies which contains clarifies, and a classwhich contains a list of capitalized adjectives likeAdvanced. The...
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Báo cáo khoa học: "Learning More Effective Dialogue Strategies Using Limited Dialogue Move Features" ppt
... user simulations used here (see(Georgila et al., 200 5a) for details and evaluationresults) treat a dialogue as a sequence of pairs of speech acts and tasks. They take as input the n− 1most ... explore the effects of differ-ent features on learned dialogue strategies.Our results show that adding the dialoguemoves of the last system and user turnsincreases the average reward of the auto-matically ... 5-gram user sim-ulations has been established through a variety of metrics and against the behaviour of the ac-tual users of the COMMUNICATOR systems, see(Georgila et al., 200 5a) .2.4.1 Limitations...
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Báo cáo khoa học: Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon a-induced early antiviral signalling pdf
... receptor, and these kinasesphosphorylate signal transducers and activators of transcription STAT1 and STAT2. In contrast to otherJAK ⁄ STAT signalling pathways, type I IFN signallingadditionally ... behaviour of the system. (A) Sensitivity analysis using the original parameter set. (B) Global sensitivity analysisusing 998 parameter sets.IRF9 accelerates IFNa signal transduction T. Maiwald ... shown to play an important role in the antiviral response [33]. Here, SOCS1 expressionwas rapidly activated and repressed, whereas the acti-vation of USP18 was sustained. These observationsare...
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Báo cáo khoa học: "EM Can Find Pretty Good HMM POS-Taggers (When Given a Good Start)∗" docx
... ambiguityclass. Our ambiguity-class guesser assigns for eachword the set of all open-class tags that appearedwith the word suffix in the dictionary. The wordsuffix is the longest (up to 3 characters) suffix ... (about 5%) contradict these basic and ap-parently simple constraints. As an alternative to these common-sense constraints, we tried to use a small seed of randomly selected sentences (10K an-notated ... unsupervised learning of stochastic processes is Hidden Markov Models(HMM). For the case of tagging, the states corre-spond to the tags ti, and words wiare emitted eachtime a state is visited....
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Tài liệu Báo cáo khoa học: The intracellular region of the Notch ligand Jagged-1 gains partial structure upon binding to synthetic membranes docx
... mm SDS), as estimated fromCDSSTR (Fig. 6). At the same SDS concentration(3 mm), the a- helical content reversibly increases as the pH decreases (17% of a- helix at pH 7.4 versus 33% atpH 6) (Supplementary ... transmembrane segment and the intracellular region expressed in COS cells was shown to localizemainly in the nucleus, and to activate gene expressionthrough the transcription factor activator ... view of the factthat most of the presenilin ⁄ c-secretase substrates con-sidered in Fig. 9 release fragments that are translocat-ed to the nucleus and are involved in transcriptionalregulation....
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Tài liệu Báo cáo khoa học: A novel type of highly negatively charged lipooligosaccharide from Pseudomonas stutzeri OX1 possessing two 4,6-O-(1-carboxy)-ethylidene residues in the outer core region ppt
... phosphatecolorimetric assays gave positive results. The LOS fraction was then subjected to both alkaline andacid degradations and complete structural characterization.NMR spectroscopy and MALDI-TOF MS spectrometry of ... G.M., Shashkov, A. S. , Knirel, Y .A. , Vinogradov, E .V. &Kochetkov, N.K. (1988) A computer-assisted structural analysis of regular polysaccharides on the basis of 13C-n.m.r. data.Carbohydr. Res. ... representative of core region- lipid A. Allsugars areD-pyranoses and a- linked, if not stated otherwise.Based on the structure found, the hypothesis can be ad-vanced that pyruvate residues are...
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Tài liệu Báo cáo khoa học: Solution structure of the matrix attachment region-binding domain of chicken MeCP2 ppt
... by the rmsdvalues given in Table 1. Analysis of the Ramachandran plotshows that the dihedral angles / and w for the secondarystructure elements are all found in the most favored or the additionally ... regions and agrees with the results of the chemical-shift analysis (see above). Additional efforts were made to confirm the helical structure of residues 153–155, as theseresidues were not always ... structureStructure calculations are based on a data set consisting of 891 different NMR-derived distance and torsion anglerestraints. Among the distance restraints, 447 intraresidual,186 sequential, and 196...
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