... 275 (2008) 3016–3030 ª 2008 The Authors Journal compilation ª 2008 FEBSREVIEW ARTICLEInsights into and speculations about snake venommetalloproteinase (SVMP) synthesis, folding and disulfidebond ... metalloproteinases (SVMPs), as thisgroup of proteinases is now named, were further cate-gorized into the PI, PIIa and PIIb, PIIIa and PIIIb,and PIV classes [4,5]. The criterion for this differentialclassification ... Although recent transcriptome and proteomestudies on venoms have provided us with tremendousinsights into venom complexity, very little is empiri-cally known about how the biosynthetic process ofnascent...