... towards a malaria vaccine.Naturally acquired immunity)imitatenature to advance the immuneresponses of malaria-naı¨ve individuals A key observation in malaria-endemic regions is thegradual ... AS0 2A candidate malaria vaccine in Gambianchildren. Vaccine 23, 4148–4157.27 Macete E, Aponte JJ, Guinovart C, Sacarlal J, Ofori-Anyinam O, Mandomando I, Espasa M, Bevilacqua C,Leach A, Dubois ... Alonso PL, Sacarlal J, Aponte JJ, Leach A, Macete E,Milman J, Mandomando I, Spiessens B, Guinovart C,Espasa M et al. (2004) Efficacy of the RTS,S ⁄ AS0 2A vaccine against Plasmodium falciparum infection...