Tài liệu Báo cáo khoa học: "Word Vectors and Two Kinds of Similarity" pptx

... constructingword vectors and the type of similarity in a sys-tematic way. Especially this study addresses threemethods, LSA-based, cooccurrence-based, and dictionary-based methods, and two kinds of sim-ilarity, ... degree to which theyreﬂect these two kinds of similarity.2 Two Kinds of SimilarityIn this study, we divide word similarity into two categories: taxonomic similarity and associativesimilarity. Taxonomic ... asthe dimension of the vectors increased as in thecase of synonym judgment, the scores of bothLSA-based and cooccurrence-based vectors hada peak around 200 dimensions, as Landauer and Dumais (1997)...

Tài liệu Báo cáo khoa học: "WORD, PHRASE AND SENTENCE" pptx

... understanding what the discourse is about. Scripts, frames, stereotypes, schemas are all studied in these areas; and often morphological and gra~natical analysis is bypassed in favor of keyword ... statistical treatment of text and with semantic analysis at the single sentence level. Yet, with regard to most of the topics in this and other sessions, there is a stronK sense of de~a vu; the ... of language at the sentence level. The most glamourous areas of natural language research are at levels above the sentence, concerned with dialogues and discourse, frequently disdainful of...

Tài liệu Báo cáo khoa học: Helix mobility and recognition function of the rat thyroid transcription factor 1 homeodomain – hints from 15N-NMR relaxation studies pdf

... dis-tribution of the energy between the overall tumbling and the internal mobility, and is indicative of thedegree of internal restraint of each15N–1H vectormotion. In Fig. 4, most of the points ... graph of R1, R2 and {1H}–15N NOE val-ues along the sequence of the TTF1 HD at 11.7 T and 286 K.Fig. S2. Plot of J(0.87xN)–J(0) correlation from15Nrelaxation measurements of the ... N-terminal and C-terminal resi-dues and the structured core of the molecule, suggesting the occurrence of a hinge point. Finally, slow-time-scale motions observed at the end of helix I, at the end of...

Tài liệu Báo cáo khoa học: Puriﬁcation and structural characterization of a D-amino acid-containing conopeptide, conomarphin, from Conus marmoreus docx

... Pro, Val or Lys, c-carboxylation of Glu, glycosylation of Ser or Thr, bromination of Trp, sulfation of Tyr, cyclization of N-terminal Gln, and epimerization of several different residues. It ... +3hydrogenbonds for Asn11(CO)–Trp14(HN) and Ser12(CO)–Thr15(HN), and conﬁrmed by the slow solventexchange kinetics of the amide protons of Trp14 and Thr15. The observation of two small3JHN-Hacou-pling ... structure of conomarphinwas similar to those of other conotoxin cDNAs. ThecDNA-encoded precursor of conomarphin consisted of a conserved M-superfamily signal peptide of 25 resi-dues, a proregion of...

Tài liệu Báo cáo khoa học: The antibacterial and antifungal properties of trappin-2 (pre-elaﬁn) do not depend on its protease inhibitory function pptx

... and the CFU counted. The per-centage of surviving CFU was calculated by the formulaN ⁄ Ncontrol· 100, where N and Ncontrolwere the numbers of CFU obtained after 3 h of incubation with and ... (2006)Secretion of serine peptidase by a clinical strain of Candida albicans: inﬂuence of growth conditions and cleavage of human serum proteins and extracellularmatrix components. FEMS Immunol Med ... exacerbations of COPD. Infection 35, 143–149.38 Higuchi R, Krummel B & Saiki RK (1988) A generalmethod of in vitro preparation and speciﬁc mutagenesis of DNA fragments: study of protein and DNA...

Tài liệu Báo cáo khoa học: Molecular modeling and functional characterization of the monomeric primase–polymerase domain from the Sulfolobus solfataricus plasmid pIT3 doc

... concentration of Rep245 pre-pared in 10 mm sodium phosphate (pH 7.4) was 5 lm. CDspectra were recorded at 60, 70 and 80 °C between 190 and 260 nm with a step increase of 0.2 nm, and a bandwidth of 1 ... 2008 FEBS 4391Zn-binding motif and the two disulﬁde bonds respec-tively connecting the a4-helix to the b4 strand and theb9 strand to the b10 strand at the bottom of theZn-stem loop in the pRN1 ... X family of human DNApolymerases, which includes the TdT enzymes and two additional members, Pol k [29] and Pol l [30]. Thelatter two enzymes are functionally malleable to thepoint of carrying...

Tài liệu Báo cáo khoa học: Tissue expression and biochemical characterization of human 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, a key enzyme in tryptophan catabolism pptx

... electrophoresis of the PCR product indicated thepresence of two distinct bands between 1000 and 1100 bp of roughly the same extent (not shown). Clo-ning and nucleotide sequencing of these two productsindicated ... software swiss-pdbviewer and visual molecular dynamics [49].AcknowledgementsWe thank G. Magni and S. Ruggieri for helpful com-ments and suggestions and T. Begley (Department of Chemistry and ... brain, no ACMSD II expression is detected, and ACMSD I is present at very low levels. Cloning of the two cDNAs in yeastexpression vectors and production of the recombinant proteins, revealedthat...

Tài liệu Báo cáo khoa học: Biochemical characterization and inhibitor discovery of shikimate dehydrogenase from Helicobacter pylori docx

... catalytic proper-ties of HpSDH and the effects of pH and temperatureon HpSDH. The results show that HpSDH has a kcat of 7.7 ± 0.9 s)1, Km of 0.148 ± 0.028 mm and kcat⁄ Km of 5.2 · 104m)1Æs)1toward ... shikimate, kcat of 7.1 s)1 and Km of 0.182 mm toward NADP, kcat of 5.2 s)1 and Km of 2.9 mm toward NAD. The optimum pH of theenzyme activity is between 8.0 and 9.0, and the optimum temperature ... expressed, and puriﬁed in Escherichia coli system. The enzymatic characterization of HpSDH demonstrates its activity with kcat of 7.7 s)1 and Km of 0.148 mmtoward shikimate, kcat of 7.1 s)1and...

Tài liệu Báo cáo khoa học: Receptor association and tyrosine phosphorylation of S6 kinases pdf

... domains and have a similar mode of activation [1].There are two isoforms of S6 kinase, S6K1 and 2.Both have highly homologous kinase and kinaseextension domains ﬂanked by the less conservedN- and ... activated by an array of mitogenicstimuli and is a key player in the regulation of cell growth. The activationprocess of S6 kinase involves a complex and sequential series of multipleSer ⁄ Thr ... phosphorylation of S6K. In addition, we mapped the sites of tyrosine phosphorylation in S6K1 and S6K2 to Y39 and Y45, respectively.Mutational and immunoﬂuorescent analysis indicated that phosphorylationof...

Tài liệu Báo cáo khoa học: Design, structure and biological activity of b-turn peptides of CD2 protein for inhibition of T-cell adhesion ppt

... bonds between NH of Thr5 and CO of Arg2, as well as NH of Arg2 and CO of Thr5.Structure of cyclic hexapeptides – cYT peptide. TheNMR data of the cYT peptide wer e indicative of its ﬂexiblenature. ... structure of peptide cERconsists of two b-turns, located at the N- and C-termini. Acomparison of the b-turn structure of cER with the similarregion in the crystal structure of rat and human ... heconformation of backbone had an interproton error of lessthan 0.2 A˚compared to upper and lower boundaries of distances from ROE/NOE data and (b) the conformationhad / angles within 30° of the...

Xem thêm