... understanding of diseases.Materials and methodsTyping of miRNAs by positional relationship tomRNA transcriptsInformation about the localization and strand direction of 939 miRNAs, 35245 Refseq genes and ... excluded from the Refseq data set.Using matlab, version 201 1a (Mathworks, Natick, MA,USA), we compared localization and strand directionbetween miRNAs and transcripts (Refseq genes and mRNAs). ... HDAC-1,whereas Bcl-6, Stat3 and YY1 are targeted by HDAC-2. By regulating both histone and nonhistone proteins,HDACs 1 and 2, classified as class I HDACs, areimplicated in cell proliferation, apoptosis...