... participatingTable 1. Amino acid frequencies (%) in a-amylase linkers, in a setof globular proteins, in the Swiss-Prot databank and in intrinsicallyunstructured proteins.Aminoacid LinkersaGlobularproteinsbSwiss-ProtcIntrinsicallyunstructuredproteinsbAla ... (Table 1).There is therefore a much weaker driving force for folding the connecting linkers when compared with aglobular protein. In addition, the main polaruncharged side chains (Asn, Gln, Ser, ... ofthis domain in recently available sequence and genomedatabanks. Interestingly, this domain was found in some closely related bacterial species, but mainly in nonvertebrate animals, and invariably...