... pacing CRT is not indicated for patients whose functional status and life expectancy are limited predominantly by chronic noncardiac conditions *All primary SCD prevention ICD recommendations apply...
... time of each measurement to assess the level of organ dysfunction [14] Dobutamine, norepinephrine requirement represented the dose of drug during the StO2 measurement Also reported is use of intra-aortic ... men; age 40 ± 12 years) were included in the control group Patients in group A received higher doses of dobutamine (Table 2) There was no difference in lactate value, haemoglobin level and leucocyte ... can track systemic DO2 during and after resuscitation of trauma patients [36] StO2 overestimated SvO2 (bias -2.5%) in the present study This may be due to the NIRS method, which does not discriminate...
... of dobutamine has a sustained beneficial effect on vascular endothelial function for two weeks or longer and after four months, respectively [25,26] Despite this effect of dobutamine on endothelial ... Treatment of patients Treatment Norepinephrine (mg/h, n) Dobutamine (μg/kg/min) All (n = 52) Treatment with dobutemine (n = 43) Treatment without dobutamine (n = 9) P value 0.09 ± 0.10 (43) 0.08 ± ... failure and additional sepsis treated with and without dobutamine Hemodynamic data All (n = 52) Treatment with dobutemine (n = 43) Treatment without dobutamine (n = 9) P value HR (bpm) 113 ± 20 113...
... signaling Procedures All treatments including milrinone dosing was at the discretion of the patient's attending physician, with initial dosing between 0.25 and 0.5 μg/kg/min Patients were observed ... example, there are studies suggesting differences in biomarker effects between dobutamine vs levosimendan [12], and dobutamine vs milrinone [13] Furthermore, there is little or no data regarding ... similar hemodynamic properties For example, dobutamine failed to decrease NTproBNP or TNF while levosimendan significantly decreased both in one randomized study [12] On the other hand, levosimendan...
... contradict several randomized studies suggesting no difference in mortality outcome between CRRT and IHD; however, these studies have methodological concerns, including failure of randomization, inadequate ... failure requiring dialysis Arch Intern Med 1995, 155:1505-1511 Manns B, Doig CJ, Lee H, Dean S, Tonelli M, Johnson D, Donaldson C: Cost of acute renal failure requiring dialysis in the inten- ... surgery Am J Med 1998, 104:343-348 Uchino S, Kellum JA, Bellomo R, Doig GS, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, et al.: Acute renal failure in critically ill patients: a...
... concentration and drug half-life are similar in patients with or without renal failure; therefore, no dose adjustment is required [9] However, no specific data are available on the safety of DrotAA, ... with severe sepsis admitted to the adult intensive care unit (ICU) at St Thomas' Hospital in London, UK We included all patients who received DrotAA for severe sepsis with two or more organs in ... mean ± SD * Impaired renal function was defined as patients receiving chronic dialysis or with documented elevated creatinine prior to current illness APACHE = Acute Physiology and Chronic Health...
... injury or illness index (NACA) score 4-7 ETI: Endotracheal intubation ED: Emergency department Table Cases of failed or complicated pre-hospital endotracheal intubation (ETI) Case ETI Successful ... esophageal and endobronchial intubations performed by emergency physicians Anesth Analg 2007, 104:619-623 Wang H, Cook LJ, Chang CC, Yealy D, Lave J: Outcomes after out-ofhospital endotracheal intubation ... hospital, ** 58 dead before arriving at hospital † Three patients in the “Attempted pre-hospital endotracheal intubation” and five in the “Not intubated” group were scored as NACA but were first...
... addition to the German TTO weights, we also calculated utilities based on the UK tariff according to Dolan [16] to compare our results with studies from other countries The second part of the EQ-5D ... specifically developed for patients with chronic airflow limitation Three component scores for the domains symptoms, activity and impact on daily life can be calculated as well as a total score [18] ... models, adjusting for age, sex, smoking status and time of assessment (admission or discharge) Random effects were employed to account for cluster effects due to multiple admissions Analyses were...
... widely between patients, the optimal dose and the optimal infusion interval for infliximab is also likely to be different from patient to patient The best dosage probably needs to be defined individually ... Activity Index J Rheumatol 1994, 21:2286-2291 Braun J, Pham T, Sieper J, Davis J, van der Linden S, Dougados M, van der Heijde D: International ASAS consensus statement for the use of anti-tumour necrosis ... Metrology Index J Rheumatol 1994, 21:1694-1698 Anderson JJ, Baron G, van der Heijde D, Felson DT, Dougados M: Ankylosing spondylitis assessment group preliminary definition of short-term improvement...
... response to gold, dermatitis after indomethacin) The histological findings were compatible with the diagnosis in all cases Perivascular infiltrations – predominantly lymphocytic – epidermal exocytosis, ... also been reported [42] TNF-αblocking therapy down-regulates Th1 immune responses [43], which might induce a shift of the Th1/Th2 balance towards Th2-dominated immune responses and which might promote ... tumor necrosis factor receptor p55-Fc IgG1 fusion protein Ro 45-2081 (lenercept): a double blind, placebo controlled dose-finding study in rheumatoid arthritis J Rheumatol 2003, 30:680-690 Welsing...
... Andrews B, Abeles M, Seibold JR: High-dose versus low-dose D-penicillamine in early diffuse systemic sclerosis: analysis of a two-year, double-blind, randomized, controlled clinical trial Arthritis ... were treated with dosages >7.5 mg/day (32.5% vs 20.2%) (P < 0.005) Dosages
... echocardiographic assessment included standard M mode, 2D and color Doppler study using Sonos 2500 system (Hewlett Packard, Andover, MA, USA) LV volumes and EF were calculated from apical two- ... obtain continuous wave Doppler recordings to measure maximal velocity across the aortic valve Maximal systolic pressure gradient over aortic valve was calculated from the Doppler velocities using ... the same approach is advised in the case of combined aortic valve disease, if the stenosis is predominant lesion [1] Following successful AVR due to AS, in the majority of the patients significant...
... feedback on treatment outcomes On the other hand, unmet needs in the domain of psychopathology did not predict a met need in the same domain at the next assessment This could have been expected, as ... functioning (GAF < 45) and needs in at least two of the four following domains: accommodation, welfare benefits, alcohol and drugs These four domains of need were a priori selected from the CAN Accommodation ... necessities of life; needs in these domains therefore indicate major problems related to independent living and justify inclusion in the SMI group Needs in the domain of alcohol and drugs indicate...
... illness The randomized controlled studies found significant weight reductions or modest reductions on body weight in patients taking antipsychotic medication [10-17] A small number of nonrandomized ... general obesity Moreover waist circumference, a well documented proxy for visceral obesity [25], was significantly decreased in our Hassapidou et al BMC Psychiatry 2011, 11:31 http://www.biomedcentral.com/1471-244X/11/31 ... JC, Lean ME: Predicting intra-abdominal fatness from anthropometric measures: the influence of stature Int J Obes Relat Metab Disord 1997, 21:587-593 Hassapidou et al BMC Psychiatry 2011, 11:31...
... Library, Issue 2; 2001: www.update-software.com Dominioni L, Dionigi R, Zanello M, Chiaranda M, Dionigi R, Acquarolo A, Ballabio A, Sguotti C: Effects of high-dose IgG on survival of surgical patients ... IgG immunotherapy in a special subgroup of septic patients has already been shown in the study by Dominioni et al [3] In conclusion, it seems that there is a subgroup of patients with severe sepsis...
... who were randomly assigned to receive placebo by 28-day survival and causative micro-organism Methods This report utilized a portion of the data collected as part of a randomized, double-blind, ... cytometric methodology Antigenic levels of TNF-α, IL-1β, IL-8, and IL-10 were measured simultaneously with validated multiplexed technique (FlowMetrix, Dynamic System Solutions, Herndon, VA, USA) ... markers of inflammation, endothelial injury, coagulation, and fibrinolysis indicate that 28-day survival in severe sepsis is associated with decreased inflammation, endothelial injury, and thrombin...
... increased intra-abdominal pressure (≥ 25 cmH2O), which is related to body weight, to be a risk factor for early organ dysfunction, and therefore they recommended monitoring of intra-abdominal pressure ... no doubt that pancreatic infection is the major risk factor in necrotizing pancreatitis with regard to morbidity and mortality’ [13] Recently, the validity of that statement was cast into doubt ... treated surgically However, there were unexpected findings that demonstrate that enclaves of heterodox practice in the treatment of SAP persist in Europe; for example, some surgeons advocated nonoperative...
... alter the incidence and severity of ARDS Chronic alcohol abuse is independently associated with a doubling in risk for developing ARDS, and once ARDS has developed it is associated with a nearly ... ICU (n = 7) in the remaining 12 patients The sources of sepsis were pneumonia (n = 16), intra-abdominal infection (n = 6), primary bloodstream infection (n = 4), and urosepsis (n = 3) The incidence ... of acute respiratory distress syndrome in adults JAMA 1996, 275:50-54 Moss M, Steinberg KP, Guidot DM, Duhon GF, Treece P, Wolken R, Hudson LD, Parsons PE: The effect of chronic alcohol abuse...