ưu điểm của loại này làm việc tin cậy chính xác và phù hợp với dai rộng vận tốc quay đến 9000 vg ph vi không dùng tiếp điểm
Sensory evaluation techniques
... Chemistry, Ms Civille began her career as a product evaluation analyst with the General Foods Corporation B Thomas Carr is Principal of Carr Consulting, a research consulting firm that provides project ... Difference and Similiarity Testing III Triangle Test IV Duo-Trio Test V Two-out-of-Five Test VI Same/Different Test (or Simple Difference Test) VII “A” – not “A” Test VIII Difference-from-Control ... (Attribute Diagnostics) VI Design of Quantitative Affective Tests A Questionnaire Design B Protocol Design VII Using Other Sensory Methods to Supplement Affective Testing A Relating Affective and...
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Báo cáo y học: "Characterization of Human Erythrocytes as Potential Carrier for Pravastatin: An In Vitro Study"
... Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors Clin Pharmacokinet 2002; 41(5):343-370 Hatanaka T Clinical pharmacokinetics of pravastatin: mechanisms of pharmacokinetic ... Erythrocyte- A Review Int J Pharm 2010; 2(1):23-30 Shavi GV, Doijad RC, Deshpande PB, Manvi FV, Meka SR, Udupa N, Omprakash R, Dhirendra K Erythrocytes as carrier for prednisolone: in vitro and in vivo evaluation ... releasing curves of pravastatin show release phases, the first is rapid release phase and the second is slow sustained release phase with hemoglobin release similar pattern Pravastatin release in PBS...
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Báo cáo khoa học: The oxidative effect of bacterial lipopolysaccharide on native and cross-linked human hemoglobin as a function of the structure of the lipopolysaccharide A comparison of the effects of smooth and rough lipopolysaccharide ppt
... shown) As was observed previously by others [5], the reaction is biphasic at pH 7.4 and below, with an initial fast phase followed by a slower phase To determine the optimum pH at which to study the ... Ana, CA, USA) and was diluted with deionized water to produce a buffer, pH 7.4, 0.1 M phosphate and 0.15 M NaCl All other phosphate buffers used were prepared from monobasic NaH2PO4 (Fisher Scientific ... by pH The biphasic reaction was shown to consist of a rapid initial reaction followed by a slower second phase over a wide pH range from 5.3 to Tsuruga and Shikama [21] confirmed that the fast phase...
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Financial Relationships and Interests in Research Involving Human Subjects: Guidance for Human Subject Protection pdf
... 56.107(e) prohibit an IRB member with a conflicting interest in a project from participating in the IRB’s initial or continuing review, except to provide information as requested by the IRB Policies ... 54.4) Note that when the PHS regulations were promulgated, the National Science Foundation (NSF) Investigator Financial Disclosure Policy was revised to match closely the PHS regulations The NSF ... who review research have no conflicting interest 45 CFR 46.107(e) directly addresses conflicts of interest by requiring that “no IRB may have a member participate in the IRB's initial or continuing...
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BELMONT REPORT: ETHICAL PRINCIPLES AND GUIDELINES FOR THE PROTECTION OF HUMAN SUBJECTS OF RESEARCH ppt
... regarding whether or not the activity requires review; the general rule is, that if there is any element of research in an activity, that activity should undergo review for the protection of human ... important to distinguish between biomedical and behavioral research, on the one hand, and the practice of accepted therapy on the other, in order to know what activities ought to undergo review for ... objective is to provide an analytical framework that will guide the resolution of ethical problems arising from research involving human subjects This statement consists of a distinction between...
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Báo cáo khoa học: Hematopoietic differentiation from human ESCs as a model for developmental studies and future clinical translations Invited review following the FEBS Anniversary Prize received on 5 July 2009 at the 34th FEBS Congress in Prague docx
... producing factor VIII, and were transplanted into mice suffering from hemophilia A The transplanted cells engrafted and expressed endogenous factor VIII protein in vivo, resulting in phenotypic correction ... Using similar methodology, another study has shown phenotypic correction of the clotting factor VIII disorder in a hemophilia A mouse model [30] Hemophilia A is a genetic blood disorder characterized ... the monocyte–macrophage lineage Retrovirology 6, 118 16 Volberding PA & Deeks SG (2010) Antiretroviral therapy and management of HIV infection Lancet 376, 49–62 17 Zhan X, Dravid G, Ye Z, Hammond...
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ETHICAL AND LEGAL ASPECTS OF HUMAN SUBJECTS RESEARCH ON THE INTERNET docx
... community, giving false information in order to study the reactions and behavior of community members Guidelines in the physical world allow for deception in the study of human phenomena, providing ... research will provide greater convenience than research in the physical world for someone with online access to participate in the study 8, It has also been shown that interviews conducted via e-mail ... interviews.9 Furthermore, Internet research enables some individuals or populations, who might not be able to or willing to so in the physical world, to participate in the research, hence giving...
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Báo cáo hóa học: " Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects" potx
... a growth factor cocktail consisting of erythropoietin (EPO, U/mL), granulocyte-macrophage-colony-stimulating factor (GM-CSF, 20 ng/mL), granulocyte colony-stimulating factor (G-CSF, 20 ng/mL), ... by visual colony counting as well as using the AlphaEase image analysis system These data suggest Stem-Kine supplementation augments circulating levels of cells that not only bear the EPC phenotype, ... mobilization induced by G-CSF or cyclophosphamide [68] Not mutually exclusive is the possibility that Stem-Kine is activating bone marrow resident macrophages, elaborating cytokines associated with...
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Báo cáo hóa học: " Are quantum dots ready for in vivo imaging in human subjects?" docx
... broader pH range [35] The third method maintains the native ligands on the QDs and uses variants of amphiphilic diblock and triblock copolymers and phospholipids to tightly interleave the alkylphosphine ... provide a robust platform for QD functionalization QDs for in vitro and cell-based applications Numerous in vitro and cell-based uses have been discovered for QDs because of their unique photophysical ... (alphafetoprotein, a marker for hepatocellular carcinoma cell lines) antibody for in vivo tumor targeting and imaging [174] No in vitro validation of the QD probe was carried out before the in vivo...
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báo cáo khoa học: " Human subjects protection issues in QUERI implementation research: QUERI Series" pptx
... along with an overview of the entire project We then submitted additional project activities for individual review in the context of the project overview This approach allowed IRB reviewers to judge ... review boards (IRBs) can and differ Central review boards, dual systems of central and local review, review boards affiliated with universities or hospitals, or un-affiliated independent review ... contact, advance phone call consent, telephone interview protocol, recording interview protocol, time estimated for interviews, why patients were being interviewed, and obtaining consent Concerns...
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Báo cáo y học: "valuation of a recombinant human gelatin as a substitute for a hydrolyzed porcine gelatin in a refrigerator-stable Oka/Merck live varicella vaccine." pps
... hydrolyzed porcine gelatin, phosphate, glutamate, and urea, as well as a live attenuated varicella virus (Oka/ Merck) and residual components of MRC-5 cells [1] Hydrolyzed porcine gelatin is a major ... exact mechanism of gelatinmediated protection to the vaccine virus is unknown It is believed that gelatin provides non-covalent and non-specific protective binding to the virus particles that enhances ... gelatin (>100,000 Da) to low molecular weight gelatin (between 2000 and 5000 Da) [4] Low molecular weight gelatin is less likely to stimulate gelatin-specific IgE than high molecular weight gelatin...
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Báo cáo khoa học: "Bench-to-bedside review: Human subjects research – are more standards needed" ppsx
... Review Boards: Their Role in Reviewing Approved Research Washington, DC: US Government Printing Office; 1998 44 Vick CC, Finan KR, Kiefe C, Neumayer L, Hawn MT: Variation in Institutional Review ... decrease costs and delays, and to provide compensation for injured individuals, a no-fault compensation system be created for individuals injured by research, as previously called for by the Institute ... publish a case series or retrospective review However, such an approach, although avoiding potentially burdensome regulation, would provide less useful and less convincing data than a formal, prospective,...
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Tài liệu Báo cáo khoa học: Trophoblast-like human choriocarcinoma cells serve as a suitable in vitro model for selective cholesteryl ester uptake from high density lipoproteins pdf
... these replicating trophoblasts, derived from the malignant tumor or produced by viral transformation of normal trophoblasts, are appropriate systems to mimick trophoblast behaviour in vitro Exogenous ... trophoblast cells develop along a cell lineage forming the villous cytotrophoblast with the overlaying syncytiotrophoblast, both responsible for hormone production and fetomaternal exchange (reviewed ... absence or presence of 300 lM 8-(4-Chlorophenylthio)adenosine 3¢,5¢-cylic monophosphate (8-CPTcAMP, Sigma, Vienna) particles only specific cell-associated radioactivity (the difference between total...
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Báo cáo khoa học: Human telomeric G-quadruplex: The current status of telomeric G-quadruplexes as therapeutic targets in human cancer pdf
... G-quadruplex-interactive potent small-molecule inhibitor of telomerase exhibiting in vitro and in vivo antitumor activity Mol Pharmacol 61, 1154–1162 55 Martins C, Gunaratnam M, Stuart J, Makwana V, Greciano O, Reszka ... Phatak P, Cookson JC, Dai F, Smith V, Gartenhaus RB, Stevens MF & Burger AM (2007) Telomere uncapping by the G-quadruplex ligand RHPS4 inhibits clonogenic tumour cell growth in vitro and in vivo ... telomestatin: in vitro and in vivo studies in acute leukemia Oncogene 25, 5719–5725 42 Fedoroff OY, Salazar M, Han H, Chemeris VV, Kerwin SM & Hurley LH (1998) NMR-based model of a telomerase-inhibiting...
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Báo cáo khoa học: Identification of carbonic anhydrase 9 as a contributor to pingyangmycin-induced drug resistance in human tongue cancer cells ppt
... solid tumors maintain a high intracellular pH (pHi) but a low extracellular pH (pHe) Adaptation of tumor cells to hypoxia and acidosis is a critical driving force in tumor progression and metastasis ... alkaline resting pHi Importantly, the efficiency of caspase activation by cytC was found to be pH- sensitive, and lower pH contributed to more caspase activation [24] The change in cytosolic pH may ... were then transferred to a poly(vinylidene difluoride) membrane, and immunoblotting 4516 Caspase activity assay Caspase activity was determined with a caspase activity kit (Beyotime), through cleavage...
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Báo cáo khoa học: Novel repressor of the human FMR1 gene ) identification ¨ of p56 human (GCC)n-binding protein as a Kruppel-like transcription factor ZF5 ppt
... a probe Electrophoretic separation of DNA-protein complexes was carried out in 5% nondenaturating polyacrylamide gels using V P Kalinovski’s device for preparative gel electrophoresis [37] Two-milliliter ... Dulbecco’s modified Eagle’s medium containing 10% fetal bovine serum, 5% CO2 at 37 °C Ca-phosphate tranfection was performed as described previously [42] Ten micrograms of DNA per dish was used in ... ultrafiltration and checked for DNA-binding activity by analytical EMSA (Fig 2C) The slower migrating complex (Complex I) spontaneously converted into the faster migrating one (Complex II) (Fig 2C) Therefore,...
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Báo cáo khoa học: Identification of NF1 as a silencer protein of the human adenine nucleotide translocase-2 gene pptx
... TGGTAATGCTCCAAGGGTTTTTGTCC-3¢; Site-3 wt, Chromatin immunoprecipitation Chromatin immunoprecipitation of NF1 from exponentially growing HeLa cells was performed as described previously [13] Immunoprecipitation ... was carried out on samples fractions from the Heparin Sepharose XK 16/20 column that contained Site-2/Site-3 DNase I footprinting activity (see above) A Superdex 200 HR 10/30 column (Amersham ... Site-2/ Site-3 (Fig 4C) In vivo occupation of Site-2 and Site-3 as revealed by chromatin immunoprecipitation (ChIP) analysis To determine if Site-2 and Site-3 are occupied in vivo, ChIP analysis was...
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Bacteria are often maligned as the causes of human and animal disease (like this one, Leptospira, which causes serious disease in livestock)
... Characterization of the virus – – – – Order: Mononegavirales Family: Filoviridae Genus: Ebolavirus Species: Ebola-Zaire, Ebola-Sudan, Ebola-Cote d-Ivoire, Ebola-Reston Morphology under electron ... conjunctivitis - rash all over body except in face ** If the patients don’t recover gradually at this point, there is a high probability that the disease will progress to the second phase, resulting ... breathing) ** Patients who progressed to phase two EHF almost always die (Ndambi et al., 1999) Late Complications: -Arthralgia - ocular diseases (ocular pain, photophobia and hyperlacrimation) - hearing...
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Báo cáo khoa học: Functional analysis of cell-free-produced human endothelin B receptor reveals transmembrane segment 1 as an essential area for ET-1 binding and homodimer formation pptx
... Strep-Tactin Spin columns (IBA, Gottingen, ¨ Germany) according to the manufacturer’s recommendations Precipitates produced CF in the absence of detergent were suspended in 1% LMPG in 20 mm phosphate ... association is initiated by hydrophobic interactions, and specific targeting or translocation systems are therefore not necessary The endothelin (ET) system is involved in many physiologic processes, such ... completely solubilized in 1% 1-myristoyl-2-hydroxy-sn-glycero-3-[phospho-rac(1-glycerol)] (LMPG) and purified by Ni-chelate chromatography Coelution of purified ETB with ET-1 The mode of CF expression,...
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