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with the aging of the population

Tài liệu Báo cáo khoa học: Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen pdf

Tài liệu Báo cáo khoa học: Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen pdf

Báo cáo khoa học

... be important for the interaction of these MT-MMPs with GRASP55. By contrast,mutation of the VTY636motif to AAA636in MT5-MMP did not affect the binding of the protease with GRASP55. Previous ... with the PDZ2domain of GRASP55. The interaction of PDZdomains with ICD internal motifs has previously beenreported. For example, the interaction of the ErbB2ICD with the Erbin PDZ domain ... reported to affect the normal trafficking of these proteins. The expression of the MT1-MMPAAA573mutant at the cell surface [18] could resultfrom the intracellular traffic of MT1-MMP via analternative...
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Aging of the Respiratory System: Impact on Pulmonary Function Tests and Adaptation to Exertion pdf

Aging of the Respiratory System: Impact on Pulmonary Function Tests and Adaptation to Exertion pdf

Sức khỏe người cao tuổi

... recoil of the lung (Fig. 2) [9]. The kyphotic curvature of the spine and the anteroposterior diameter of the chestincrease with aging, thereby decreasing the curvature of the diaphragm and thus its ... Conversely, there is a progressive decrease invital capacity to approximately 75% of best values.Because of the increased stiffness of the chest wall, the age-related diminished elastic recoil of the ... F, et al. Quality control of spirometry in the elderly. The S.A.R.A. study.SAlute Respiration nell’Anziano = Respiratory aging of the respiratory system 481 Aging of the Respiratory System: Impact...
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The Bravest of the Brave or, with Peterborough in Spain pot

The Bravest of the Brave or, with Peterborough in Spain pot

Khoa học xã hội

... invasion of England. He pushedhis arguments with fiery zeal, urged the disaffection of all classes, the hatred of the Commons, the defection of the Lords, the alarm of the Church, and the wavering ... Bay, at the mouth of the Guadalaviar, on the Valencian coast. On the other side of the roadstead stood the castle and village of Denia. The expedition was received with good will by the people, ... and a few of the other men availed themselves of the permission to escape for a time from the stifling atmosphere below, and made their way on deck. For a time the rush of the wind and the wildconfusion...
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Manhood Perfectly Restored, by Unknown This eBook is for the use of anyone anywhere at no cost and with almost no restrictions whatsoever. You may copy it, give it away or re-use it under the terms of the Project Gutenberg pptx

Manhood Perfectly Restored, by Unknown This eBook is for the use of anyone anywhere at no cost and with almost no restrictions whatsoever. You may copy it, give it away or re-use it under the terms of the Project Gutenberg pptx

Sức khỏe giới tính

... setforth in the Old Testament,probably one-half of the married men of the present dayAll our Doctors are Regular Graduates,and their Diplomas are Registered in the Office of the County Clerk, ... is the mostcommon cause, and we therefore give it the most prominence. The others we willname briefly in about the order of theirfrequency.1. MARRIAGE EXCESSES.—A very the reputation of ourphysicians ... honor, honesty and fair dealing of the Agency. We court the fullest andfreest investigation, either by patientsthemselves or any friends of theirs inthis city, either of whom we shall behappy to...
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Báo cáo khoa học:

Báo cáo khoa học: "Parsing with Treebank Grammars: Empirical Bounds, Theoretical Models, and the Structure of the Penn Treebank" ppt

Báo cáo khoa học

... NN:[2,3])3.1 Time The parser has an theoretical time bound,where is the number of words in the sentence to beparsed, is the number of nonterminal categories in the grammar and is the number of (active) ... shows the effect of the tree transforms ontraversal counts. The NOUNARIES settings are muchmore efficient than the others, however this efficiencycomes at a price in terms of the utility of the ... NOTRANSFORM),then the question of whether this alignment of with matches is determined entirely by the tags. However, with our assumptions, the probability that a randomlychosen set of tags matches...
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A REPORT PREPARED BY THE DEPARTMENT OF THE TREASURY WITH THE COUNCIL OF ECONOMIC ADVISERS docx

A REPORT PREPARED BY THE DEPARTMENT OF THE TREASURY WITH THE COUNCIL OF ECONOMIC ADVISERS docx

Cao đẳng - Đại học

... reauthorization of the surface transportation program and the creation of a National Infrastructure Bank. In support of this commitment, the Department of the Treasury, with the Council of Economic ... conditions); the higher the TTI index, the larger the share of peak travel time that is subject to congestion. The TTI is independent of the total amount of peak travel – it simply measures the fraction ... intimate community of interests, the most remote quarters of the United States. No other single operation, within the power of Government, can more effectually tend to strengthen and perpetuate...
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A REPORT PREPARED BY THE DEPARTMENT OF THE TREASURY WITH THE DEPARTMENT OF EDUCATION ppt

A REPORT PREPARED BY THE DEPARTMENT OF THE TREASURY WITH THE DEPARTMENT OF EDUCATION ppt

Cao đẳng - Đại học

... the lower end of the income distribution, increased levels of education do not make them as likely to end up in the top part of the distribution as someone who was born into the upper end of ... $100,000. The refundable portion of the AOTC almost exclusively benefited households at the lower end of the income distribution, with approximately 89 percent of the benefit going to households with ... student populations than four-year schools, and these students now constitute the bulk of the student population at for-profit schools. Eighty percent of students at for-profit schools are the...
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Báo cáo Y học: The role of the second binding loop of the cysteine protease inhibitor, cystatin A (stefin A), in stabilizing complexes with target proteases is exerted predominantly by Leu73 pdf

Báo cáo Y học: The role of the second binding loop of the cysteine protease inhibitor, cystatin A (stefin A), in stabilizing complexes with target proteases is exerted predominantly by Leu73 pdf

Báo cáo khoa học

... loss of a number of interactions with the enzyme and therefore to considerably decrease the contribution of the second binding loop of cystatin A to the inhibition of target proteases. However, the ... Search FixingÕ of the side chains within the Leu73–Asn77 segment in the second binding loop of cystatin A. After each of these steps, the conformation of the second binding loop in the complex was ... reaction, with  80% of the enzymebeing saturated with the inhibitor. The substrate was thenadded to a final concentration of 100 lM with minimaldilution of the complex. Alternatively, the complex...
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The Eve of the Revolution, A Chronicle of the Breach with England doc

The Eve of the Revolution, A Chronicle of the Breach with England doc

Khoa học xã hội

... period in the garret of TomDawes's house. "There they smoke tobacco till you cannot see from one end of the garret to the other. Therethey drink flip, I suppose, and there they choose ... toestimate the value of colonies in terms of what they could buy, and not merely, as of old, in terms of whatthey could sell. From this point of view, the superiority of the continental over the insular ... most part earned their bread by the sweat of their brows, lived the life and esteemed the virtues of a primitive society, and braced their minds with the tonic of Calvin's theology a tonic...
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the effect of the hydrothermal treatment with aqueous naoh solution on the photocatalytic and photoelectrochemical propertiesof visible light-responsive TiO2thin films

the effect of the hydrothermal treatment with aqueous naoh solution on the photocatalytic and photoelectrochemical propertiesof visible light-responsive TiO2thin films

Vật lý

... that the surface morphology of Vis-TiO2/Tiare drastically changed from the assembly of the TiO2crystallites to the stacking of nanowires with diameters of 30–50 nm with increasinghydrothermal ... found that the hydrothermal treatment of the Vis-TiO2/Ti with NaOH aqueous solution led to the drastic increase in the surface area of Vis-TiO2/Ti as well as an enhancement of the anodic ... in the modification of the electronic properties, thus, enabling the absorption of visible light.Fig. 2 shows the anodic photocurrent of the NaOH(X)-Vis-TiO2/Ti electrode as a function of the...
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The Eugenic Marriage, Vol 2 (of 4), by W. Grant Hague This eBook is for the use of anyone anywhere at no cost and with almost no restrictions whatsoever. You may copy it, give it away or re-use it under the terms of the Pro pptx

The Eugenic Marriage, Vol 2 (of 4), by W. Grant Hague This eBook is for the use of anyone anywhere at no cost and with almost no restrictions whatsoever. You may copy it, give it away or re-use it under the terms of the Pro pptx

Sức khỏe giới tính

... reproductive organs atpuberty The female generative organs The function of the reproductiveorgans The age of puberty in the female The function of the ovary The function of the womb—Why—Venereal ... futuremother—Motherhood the highestfunction of the sex—Health the onenecessary essential—Symptoms of the first, or beginning menstruation The period of puberty in the female—Changes in the reproductive ... vesicles, testicles, and of the kidneys. Gonorrheal rheumatism mayfollow, and even disease of the liningmembrane of the heart, and death.that the combined ravages of the GreatWhite Plague,...
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Báo cáo khoa học: Characterization of the interactions of the nephrin intracellular domain Evidence that the scaffolding protein IQGAP1 associates with nephrin potx

Báo cáo khoa học: Characterization of the interactions of the nephrin intracellular domain Evidence that the scaffolding protein IQGAP1 associates with nephrin potx

Báo cáo khoa học

... of the Ig superfamily and the first identified component of the slit diaphragm that forms the criticaland ultimate part of the glomerular ultrafiltration barrier. The extracellulardomains of the ... nephrinor in the regulation of contacts with the cytoskeleton.Tyrosine phosphorylation in the C-terminal half of nephrin has more likely this kind of functions.Having confirmed the functionality of GST–nephri-ncyt, ... on the stage of a light microscope to give a spray-ing orifice of  5 lm. The needle voltage was optimized in the range 900–1700 V, with the cone voltage set at 40 V.For the acquisition of collision-induced...
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Báo cáo khoa học: Site-directed mutagenesis and footprinting analysis of the interaction of the sunflower KNOX protein HAKN1 with DNA ppt

Báo cáo khoa học: Site-directed mutagenesis and footprinting analysis of the interaction of the sunflower KNOX protein HAKN1 with DNA ppt

Báo cáo khoa học

... of the interac-tion of helix III of wild-type and mutant HAKN1 homeodomains with DNA. The model was constructed with the programSWISS-MODEL [41] using the structures of the DNA complexes of ... towards the 3¢ end of the topstrand and the 5¢ end of the bottom strand (Fig. 4B).This agrees with the presence of a larger residue thatmakes stable contacts with this region of DNA. The interaction ... calculate the position of the footprint. Letters to the right of eachpanel indicate the DNA sequence (5¢ end in the upper part) of the corresponding strand in this region. In the lower part, the sequence...
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Báo cáo Y học: Chimeric receptor analyses of the interactions of the ectodomains of ErbB-1 with epidermal growth factor and of those of ErbB-4 with neuregulin potx

Báo cáo Y học: Chimeric receptor analyses of the interactions of the ectodomains of ErbB-1 with epidermal growth factor and of those of ErbB-4 with neuregulin potx

Báo cáo khoa học

... investigate the roles of the extracel-lular domains (I–IV) in the ligand specificities. As compared with ErbB-1 and the chimeras with both domains I and III of ErbB-1, the chimeras with only one of these ... of the receptors was confirmed byimmunoblotting of the cell lysates (Fig. 1B). As oftenobserved for membrane proteins, the bands were ratherbroad in the blots, due to the heterogeneity of the ... activated the chi-meras with either domain I or III of ErbB-1. In contrast,NRG activated the chimeras with the ErbB-4 domain I and the ErbB-1 domain III, but not those with the ErbB-1domain I and the...
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The State of the Population in the Western Cape Province potx

The State of the Population in the Western Cape Province potx

Khoa học xã hội

... weighting the ratios by the number of deaths in the respective categories in each of the health districts. A linear trend was then fitted to the index over the period in Cape Town and in each of the ... below the age of 15 years. Based on the 2001 census, the population of Cape Town is predominantly coloured (48%) and African (32%), with the white population making up 19% and the Indian population ... 1.5%. There are marked differences between the population structures of the four population groups in Cape Town. The African population is 6 Mortality rates in the other years were compared with...
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