... [20,21] Therefore, it is likely that other factors combine with the properties ofthe mucus itself to produce the putative reduction in mucociliary clearance in CF Duringthe later stages of disease, ... spite of marked reduction of cross sectional area ofthe airway surface from the alveoli tothe http://respiratory-research.com/content/4/1/8 trachea ENaC is downregulated by functional CFTR: in the ... that there may be CFTR expression in the alveolar epithelium [5], and someofthe migratory cells in the lung as well, including lymphocytes [6] However, the most obvious defects in the lungs of...
... had full access to all ofthe data in the study, and takes responsibility for the integrity ofthe data and the accuracy ofthe data analysis JF participated in the design ofthe project BRW ... 52.9 years for others Patients under 50 years of age made up 41% ofthe former cohort (N = 62/ 150) and 50% ofthe latter (N = 57/115); among the patients with invasive tumors, these fractions ... were still more likely than theothersto be in the latter group (40% vs 26%, respectively, p < 05) Despite these notable race-based discrepancies in level of insurance coverage, there was no significant...
... discounts, the price tothe consumer does not reflect these dimensions of product differentiation Moviegoers normally pay one price for all movie tickets, regardless ofthe popularity ofthe movie, the ... change in the ratio of newly released to re-issued movies The general upward trend in admission prices is due tothe contraction ofthe market for low-price B and C movies, the collapse ofthe uniform ... and the relatively inelastic demand of audiences that continued to patronize the theaters The combination of these factors allowed theaters to select attractive movies, to show early runs, and to...
... dimensions of product differentiation Moviegoers normally pay one price for all movie tickets, regardless ofthe popularity ofthe movie, the day ofthe week, and the time ofthe year The analysis ofthe ... patronize the theaters The combination of these factors allowed theaters to select attractive movies, to show early runs, and to raise pricesThe industry’s gravitation toward A movies duringthe post-Paramount ... in the persistence ofthe practice The paper continues as follows Section presents the puzzle of uniform prices at the movie theater, studies the patterns ofthe demand for movies at the theater,...
... more specifically, the time required from pollination tothe fall ofthe rape-fruit They are: 1) the biotype of annual maturation ofthe acorn (short cycle) and 2) the biotype of biennal maturation ... season, while those ofthe red oaks (Erythrobalanus) require seasons The existence in cork-oak ofthe different reproductive strategies, the ’annual’ (similar to that ofthe Lepidobalanus group) ... flowering is the end of spring and early summer when the possibility of frosts has been reduced The long period of dormancy and theof reactivation of development also appear to be optimal for the climatic...
... clear sense of direction tothe activities ofthe organization and tothe job behavior of managers and others It strengthens their confidence in understanding where the organization is heading ... best to make the organization move along the chosen path, and when should they take what measures to achieve the goals ofthe organization Provides opportunity to analyze alternative courses of ... act, to take hold initiatives, to anticipate crises and threats and to ward them off, to perceive and seize opportunities ahead of other competitions, and to gain a competitive lead over others...
... not work together and often discuss Quang realized that they frequently quarreled and accused each other of interfering in the work ofothersThe fact that, they are so uncooperative that they affect ... leaving the other to feel defeated The "loser" in these situations may feel that the other person emerged victorious due to her favored status, especially if the conflict mediator was forced to choose ... prone to conflict The result of conflict can lead to mutual animosity However conflict can be the engine of development If you know how to solve them scientifically, then they are one ofthe breakthrough...
... students I told them that I was going to address this distinguished group My women students got together and said, “Here are the kinds of things we would like for you to share with them: Mentoring ... so at the request ofthe Council ofthe National Academy of Sciences (NAS) on which I currently serve as a member Every year at the annual meeting the women members ofthe NAS get together to discuss ... then the faculty, then the tenured faculty, then chaired professors, then the upper administration, and then members ofthe National Academies of Sciences and Engineering You find a group distribution...
... in Other Sectors ofthe Economy How does naval ship and weapon system cost escalation compare to other sectors ofthe economy? To examine this, we compare it with the Department of Defense (DoD) ... center sponsored by the Office ofthe Secretary of Defense, the Joint Staff, the Unified Combatant Commands, the Department ofthe Navy, the Marine Corps, the defense agencies, and the defense Intelligence ... Comptroller’s historical deflator, the gross domestic product (GDP) deflator, and with the BLS Consumer Price Index (CPI) DoD Deflator The DoD Comptroller publishes a deflator for the purposes of forecasting...
... centers sponsored by the Office ofthe Secretary of Defense, the Joint Staff, the Unified Combatant Commands, the Department ofthe Navy, the Marine Corps, the defense agencies, and the defense Intelligence ... Although the government has some control on negotiating fee levels, it does not set market expectations for the firms or the level of return the companies must demonstrate to their shareholders Rather, ... rate The regression approach fits the natural logarithm of cost (the dependent variable) as a function ofthe fiscal year (the independent variable) The annual rate is the exponential ofthe coefficient...
... for the changes in prices and reimbursement, the hospital hires a third‑party contractor that studies thepricesof other hospitals in the area to make recommendations for changes topricesof ... facility to provide notice to, and obtain written approval or a waiver from, the Office ofthe Attorney General (attorney general) prior to entering into an agreement to sell, or otherwise dispose of, ... understand what they consider as costs of uncompensated care and how they calculate the costs Tothe extent possible, examine whether the purchases of nonprofit hospitals and the consolidations of community...
... Rotterdam, Stockholm, and Vienna, the four regions that are dominated by large urban areas, is always grouped in the upper part ofthe tables to make identification ofthe special characteristics of these ... output does not rise in proportion to R&D input The elasticity should increase as the quality of inputs tothe R&D process improves and the spillovers stemming from the R&D activities of other actors ... the proportion of enterprises that have implemented at least one process innovation The ratio of new products5 tothe total number of products supplied by an enterprise indicates the amount of...
... distasteful to any bird which attempts to eat it Most learn to avoid them altogether Those that attack them quickly spit them out and then avoid othersofthe same kind One consequence of countering these ... cockatoos attacking his crop As soon as the seeds start to germinate the cockatoos move in They walk down a row of emerging seedlings, pull them out ofthe ground, eat just the base ofthe new ... stark contrast to that of carnivores, is the time they spend eating, the volume of food they consume, and the consequent volume of faeces they produce They spend the greater part of their lives...
... first factor, the second factor, or both, with few participants loading on neither ofthe factors (shown in the center ofthe plot) The Population Preference Function Given the range of individual ... right ofthe square itself, to a more horizontal rectangle, and the peaks ofthe beta factor, corresponding tothe rectangle factor here, are not precisely at the Golden Section but are shifted to ... it conceivable that duringthe act of viewing the golden rectangle we add the width tothe height and obtain the straight line representing the sum? The intellectual factor does not seem relevant...
... the top ofthe tower of Pisa, oVered the following account ofthe event: The stone computes, in accordance with the law soon to be formulated by Newton (a formula the stone knows innately), the ... common Why did the inventive genius ofthe Wright brothers not enable them to design a 747 straight oV the bat? If we ignore the time scale, the path from the Kitty Hawk ‘‘Flyer’’ tothe supersonic ... steam to escape and lowers the pressure The machine slows down As the speed eases, the wings come down and the valve closes, which drives the pressure up again The cycle begins again, keeping the...
... according to their purchasing power they are termed hard, soft and weak Though coins and notes are issued by the Government ofthe country, there is a limit to their minting Let us see why money ... toThe same money which could help bring relief tothe suffering million, can be used to build up armaments The hope of getting money spurs one into action The power decides how to spend the ... enough to spare must look upon himself as the trustee ofthe money and see to it that it is spent in a wise and useful way There is nothing good or evil about money It depends on how one puts it to...
... All of these items, whether they are designed to help us in the kitchen, comfort us in the bathroom, or improve the way we look and feel, are for the most part unnecessary Rather than improve the ... you from the hard bottom ofthe tub as you bathe Of course if it gets mildew on it It might be better located in the trash can Finally you can sit in comfort on the toilet on a plush toilet seat ... Although these devices may save time in the actual cutting, just think of how much time the person lost trying to find the device in the first place and the cleaning it up afterward The same...
... infants of atopic mothers (for TLR-2, p 014; TLR-3, p 048; and TLR-4, p 014), with no significant effects of smoking in the nonatopic group Although there was a trend in the nonatopic group for ... preserves the response to R-848 J Immunol 2004;173:4627–34 De Wit D, Tonon S, Olislagers V, et al Impaired responses to tolllike receptor and toll -like receptor ligands in human cord blood J Autoimmun ... Toll -like receptors in the induction ofthe innate immune response Nature 2000;406:782–7 Caramalho I, Lopes-Carvalho T, Ostler D, et al Regulatory T cells selectively express toll -like receptors...
... components ofthe host immune and inflammatory response Statins modify endothelial dysfunction – effects on inflammatory initiation and perpetuation via endothelial cells Effects of statins on endothelial ... anti-inflammatory and immunemodulatory properties that might be of importance to their efficacy in the prevention and treatment of cardiovascular disease With the recognition ofthe critical role of vascular ... rheumatoid disease activity itself and are likely to be beneficial in the long-term management of patients at higher risk of cardiovascular disease Our group recently reported the findings of a double-blind,...