... that chemists can t understand one another because the physical chemists speak a different jargon from synthetic organic chemists and so on And he says that biologists are better off because most ... them So here’s a simple idea: At every big meeting of the American Chemical Society and the American Physical Society and so forth, there ought to be a special plenary lecture by a biologist, one ... start with an introduction to some important area of biology and end with a list of some of the major outstanding problems in that area and what sort of things would help get them solved That way,...
... receptor phosphatase LAR [23] In addition, it has been proposed that glypicans canbe involved in the uptake of polyamines [24] Glypicans can also be shed into the extracellular environment This ... extracellular environment, glypicans can also befound in the cytoplasm In particular, there have been several studies reporting the presence of GPC3 in the cytoplasm of liver cancer cells [34,35] Whether ... of glypican-5 and chromosomal localiza tion of human GPC5, a new member of the glypican gene family Genomics 1997, 40:24-30 44 Paine-Saunders S, Viviano BL, Saunders S: GPC6, a novel member of...
... derived profile identified additional candidate members of the PerR regulon, alkyl hydroperoxide reductase ahpC in D vulgaris (D desulfuricans has no ortholog of ahpC), and a hypothetical gene of unknown ... novel set of genes involved in biotin synthesis Regulation of metal-ion homeostasis A number of regulators believed to be involved in metal-ion homeostasis were identified on the basis of orthology ... alternative cofactor adaptation These profiles were used to scan the set of palindromes again, and the procedure was iterated until convergence Thus a set of profiles was constructed The profile with...
... number of non-unicast packets received by the interface ifInErrors The number of errors found on received packets ifOutOctets The number of bytes sent by the interface ifOutUcastPkts The number ... to modify the behavior of the utility There are lots of options that canbe used with all of the net-snmp utilities To see a complete list of the available options, you can refer to the man page ... library T I P Besides the most current production version of winpcap, there is often a development version of winpcap available for testing As with all development software, you should be careful...
... bumps or hard areas that might be a cancer The prostate gland is found just in front of the rectum, and most cancers begin in the back part of the gland, which canbe felt during a rectal exam ... chance of having prostate cancer is over 50% and increases more as your PSA level increases The PSA level can also be affected by a number of factors other than prostate cancer: It rises with non-cancerous ... But about 15% of men with a PSA below will have prostate cancer on biopsy If your PSA level is in the borderline range between and 10, you have about a in chance of having prostate cancer If it...
... microplate horn for PCR tubes Ninety microliters of NBH or 0.2 mgỈmL)1 rPrP were mixed with 10 lL of various concentrations of ScBH in a volume of 100 lL in 0.2 mL PCR tubes The tubes were positioned ... converted into a PK-resistant isoform in the presence of NADPH Aliquots of ScBH of SHa-263K were serially diluted into solutions of rSHaPrP or rHuPrP, with final ScBH dilutions of 10)3, 10)4, 10)5 and ... round of PMCA consisted of 24 cycles (24 h), which was considered to be more efficient at increasing PrPSc aggregation [19] and allowed low levels of PrPSc to be detected [23] After one round of...
... mutations have been found to cause altered trafficking of Cx43 For example, the C260fsX306 mutation (leading to truncation of most of the Cx43 cytoplasmic tail) and the G60S mutation have been found to ... distribution of Cx43–eYFP This analysis confirmed that the majority of the signal is found on the basolateral surface of cell lines expressing WT Cx43–eYFP, although there appeared to be a small amount of ... biotinylation The percentage of signal found on the basolateral surface of Y286A, LSYTRF and L90V was significantly different from that of WT (*) Error bars indicate SEM n = 3–6 (varies between cell lines)...
... the other hand canbe more easily recorded Thus the IR technique is especially suitable e.g for relatively short-term testing of methods, while limited number of thermocouples canbe applied for ... absence of sap flow this axial distance should be named aax In presence of sap flow there will be thermal conduction along a similar distance aax , but in addition there will be a displacement of heat ... fact, be a reliable strategy towards a reasonably accurate continuous determination of sap flow rates through the dynamics of ellipses? Since it could be shown that the dynamics of ellipses of isotherms...
... a high number of TIL in colorectal cancer is strongly associated with a favorable outcome in the patients with colorectal cancer [15-18] Among them, the density of TIL was shown to be positively ... clinical effectiveness of CRT for advanced rectal cancer For the cases with low TIL, other anti-cancer drugs may be useful instead of 5Fu based drugs combined with RT Also, addition of biological response ... software, and p-values less than 0.05 were considered to be statistically significant Results The number and distribution of T cells in biopsy samples before CRT were evaluated with immunostainig withm...
... reporting American Journal of Infection Control 2007, 35(3):145-149 47 Althabe F, Buekens P, Bergel E, Belizán JM, Campbell MK, Moss N, Hartwell T, Wright LL, Guidelines Trial Group: A behavioral ... especially in basic health facilities where supplies of running water may be limited [21,28,29] Systematic reviews have not however, found an established link between use of hand hygiene products and ... use of benchmarking to identify better and less well performing institutions have also been proposed [26,34,46] The effect of introducing opinion leaders to motivate and change the practice of...
... considered abnormal An abdominal CT scan is of great help in diagnosing and detecting the etiology of intestinal obstruction in 73–95% of cases [1012] A CT scan may also be able to demonstrate the foreign ... confirm the presence of a duodenal anomaly Duodenoduodenostomy or duodenojejunostomy should be performed after removal of the foreign object(s) However, in spite of the persistence of the radio-opaque ... loops ofpresence of ain the left Plain radiograph of the abdomen showing the metallic foreign body in the right lower quadrant, the presence of a 'double bubble sign', and a few dilated loops of...
... epithelium may be one of several mechanisms of recruitment and activation of neutrophils in the airways When both responders and nonresponders were considered together, a significant correlation between ... and/or oxidative stress canbe observed also in asthmatic subjects who not functionally respond to ozone The low rate of functional response canbe due to the blunting effect of the previous regular ... scientist can read your work free of charge "BioMed Central will be the most significant development for disseminating the results of biomedical researc h in our lifetime." Sir Paul Nurse, Cancer...
... clinically relevant because it may be used for point -of- care testing to assess fluid volume Key messages • • IDVG has been proposed to be an indirect measure of cardiac preload without significant ... of patients receiving mechanical ventilation 26 Number of patients receiving catecholaminesa 14 Number of patients receiving insulinb Number of patients receiving on continuous haemodiafiltration ... volume of glucose (IDVG), determined using injection of a small amount of glucose (5 g), as a measure of central extracellular fluid volume status [1-3] Neither the plasma glucose values present before...
... the onset of tissue hypoxia [6,7] Thus, for antioxidant strategies to be effective, they must be administered as soon as possible after the onset of shock So what is the optimal dose of selenium ... Laviolle B, Annane D, Vitoux D, Bleichner G, Korach J-M, Cantais E, Georges H, Soubirou J-L, Combes A, Bellissant EB: Effects of high doses of selenium, as sodium selenite, in septic shock: a placebo-controlled, ... first dosing study of its kind that asked this specific question: What is the optimal dose of selenium and other antioxidants in critically ill patients? We studied a range of doses of selenium from...
... 2007 A 'best estimate' of approximately 70,000 was deducted from Dili's population in view of displacement of Dili's residents to districts inside Timor-Leste's territory The exact number of displaced ... provision of microscopy and RDT services in camp settings As a result of this policy, a number of 24-hour fixed clinics had to be closed down in July 2006 with the intention that the IDPs can use ... Ministry of Health, RDTL; 2005 The Global Fund: Program Grant Agreement between the Global Fund to fight AIDS, Tuberculosis and Malaria and the Ministry of Health of the Government of the Democratic...
... onset of professional activity, working area, population of working city, and distance between their office and the nearest university hospital ICU In addition, information concerning the number of ... kind of information has been shown to be preferred to written letters [10] However, the efficiency of such practices requires further assessment The implementation of such practices cannot be envisaged ... point has been well explored, especially regarding end -of- life decisions [1,17,18] This could beof particular importance in France, as half of families not want to participate in end -of- life decisions...
... interactions canbe used to identify novel components of molecular pathways and can reveal the redundancy that underlies the robustness of genetic networks Thus, although analyzing the loss -of- function ... feeding we can identify the majority of a testset of previously described genetic interactions We used this technique to provide the first large-scale analysis of the redundant functions of duplicated ... redundancy between these 14 genes has been maintained for more than 80 million years of evolution merely as a consequence of the rate of neutral evolution, that is, that there has been insufficient...
... described above To compute the position of the cluster, we calculated the distance between the start of the protein and the start of the cluster, and between the end of the cluster and the end of ... clusters of consensus matches, but that there is some subset that canbe predicted in this way In order to estimate the number of CDK consensus cluster containing proteins that canbe recognized ... addition of the least significant term to the model The total numbers of proteins in each set are slightly smaller than that reported [11] because since the time of that study proteins have been...
... reactions The preparation of polymeric materialscanbe used to illustrate many of the fundamental concepts of organic chemistry Inclusion of some treatment of polymeric materials serves to stimulate ... world of science Further, they are the single most important class ofmaterials Polymers are the materialsof life, of commerce, of health, of communication, etc Polymers are a natural bridge between ... to be integrated into foundational courses Goal: To enhance foundational courses through integration of macromolecules/polymers into foundational courses Four groups of scholars, one for each of...
... calculated to be 0.881 (0.86-0.903).(Figure 2) The coordinates of the curve confirmed that a cut-off score of 4.0 provides the best combination of sensitivity and specificity for the prediction ofrelevant ... detecting the presence and recurrence of hemodynamically relevant CAD Materials and Methods Data from three published trials of the use of MCG in the identification ofrelevant coronary stenosis was ... case of prior PCI, patients with relevant stenosis were identified correctly by MCG 89% of the time and in the case of prior CABG, patients with relevant stenosis were identified correctly 93% of...