... to plant metabolism, stressresistance, growth and development [1–3]. There isgreat interest in dissecting the processes that are involved in the sugar sensing and response pathwaysallowing plants ... metabolized. Invertases (INVs) can in uence plant growth and development either directly (e.g. by in uencing source–sink relationships or by acting as a true regulatory protein)or indirectly via ... invertases are activated, and glucose is not utilized in cells) , glucose diffuses freely into the nucleus, where it binds to nuclear AtHXK1. Glucose binding triggers a conformational change in...
... entry point for carbon into the Krebs cycle. Theregulatory properties of mtPDC have been specialized tominimize activity in an environment where ATP levels are high. Plantcells contain an mtPDC ... concerning the regulatorycomplex in animal cells, there is very little comparableinformation about plant cells. It remains a challenge tounderstand how metabolism can be regulated in a complexeukaryote ... compartmentation. Plantcellsare unique in having two distinct, spatially separated forms of the PDC;mitochondrial (mtPDC) and plastidial (plPDC). ThemtPDC is the site of carbon entry into the tricarboxylic...
... currently on-going 8 Priority areas for action ã Focused Antenatal Care ã Intrapartum Care ã Emergency Obstetric and Newborn Care ã Routine Postnatal Care ã Newborn care ã Infant and Young ... report they have serious problems accessing in health care 2 MNCH In the beginning ã Implementation of disease specific programs ã vertical in- service training of health workers ã Government ... and new thinking on fast tracking comprehensive actions to change the course of maternal and child health ã proposes a new way of thinking, resourcing and putting to action a minimum range...
... paraformal-dehyde in NaCl ⁄ Piat room temperature for 30 min. For Tfinternalization, cells were first incubated for 90 min in DMEM without fetal bovine serum, next incubated at 4 °C in cold DMEM containing ... participate in theendocytic process of GD3 in MDCK cells. ABCFig. 5. GD3 and GM1-CTx are internalized in MDCK cells by clathrin-independent endocytosis. (A) GD3-expressing MDCK cells were ... proteins are seg-regated into separate transport vesicles within the TGNby virtue of sorting signals within the protein [13]. Spe-cifically, the apical targeting of proteins within MDCKcells...
... of infrastructure and information systems to microfinance institutions) Refinancing or commercial loans to sustainable microfinance institutions Acquisition of a stake in microfinance institutions ... resources is intensifying. Financial costs are rising, albeit slowly, and institutions are outgrowing the pool of available funds. Savings services are glaringly absent from the market in light ... hidden role in pushing the frontier to widen access to financial services. Also in Africa, savings banks (including postal savings banks) are progressively moving away from narrow banking to diversify...
... is leading an inspiring fight for justice, despite the terrifying obstacles. Canada must join and support them by actively fighting impunity from within its own borders, in international arenas ... and lucrative mineral wealth found in the areas under their control.141 Because Canadian companies are major investors in the DRC’s mining industry and were accused of wrongdoing there and ... personnel at a time.42 Mining and investments To prove his independence from the international forces that supported him in overthrowing Mobutu in 1997, the newly inaugurated President Kabila...
... addition to globin and other protein-encoding mRNAtranscripts [12], miRNA species in circulating erythroid cells are differentially expressed in association with hemo-globin switching. Among the ... let-7 in adult erythroid cells. We speculate thatlet-7 or other differentially expressed miRNA are involved in the hemoglobin switching phenomenon. Alternatively,the increased let-7 expression in ... transcription regula-tion in erythroid cells. Since miRNA represent a new classof transcription regulators in eukaryotic cells, human cir-culating erythroid cells were used to determine whetherfetal-to-adult...
... during training; awarding degrees uponcompletion; extensive training and research opportunities made available to graduates; and the social capitalacquired during training.BackgroundA key ingredient ... undergraduate train-ing is shown in Table 1. The majority of trainees in both programs were medical doctors.Retention within home country after trainingOf all FETP graduates, 85% are working within theirhome ... field-based training model adoptedby FETPs. FETPs focus on competency-based trainingand field training, with trainees spending 70-75% of theirtime at a field site, which may be a district or provincialhealth...
... replication and the onset of viral CPE in Vero cells are synergistically inhibited by interferon combina-tion. Whereas, individual cytokines were weak inducers of BioMed CentralPage 1 of 10(page ... tract.Methods Cells and virusesVero cells were grown in Eagle's minimum essentialmedium supplemented with 5% inactivated calf serum(MEM 5%) and gentamycin (50 μg/ml) at 37°C in 5%CO2 and maintained ... are depicted in Figure 3a. The antiviraleffect due to interferon alone or in combination is 2-foldincreased incells pretreated with CDM, as an indicationthat CDM treatment did not interfere...
... on the premise that COX-1predominates in the stomach, yielding protectiveprostaglandins, while COX-2 is induced in inflammationgiving rise to pain, swelling and discomfort. It has nowbeen unequivocally ... preconditioning in rabbits, they demonstrated that ischemic precondition-ing resulted in a rapid increase in myocardial COX-2mRNA levels. This was followed by an increase in COX-2protein expression ... doxorubicin-medi-ated cardiac injury in vivo. J Clin Invest 2001, 108:585-590.10. Cheng Y, Austin SC, Rocca B, Koller BH, Coffman TM, GrosserT, Lawson JA, FitzGerald GA: Role of prostacyclin in...
... Farming of Antibodies in Plants 39MinibodyFab fragment Single chain Fv fragment (scFv)Diabody Bispecific scFvCamelid heavy chainscFv-fusionSingle variable domainLarge single chainAntigen ... Overcoming Rate-Limiting StepsThe most important aspects in metabolic engineering are to identify enzymes thatmay be involved in intermediate biosynthesis and subsequently to determine ifany ... resistance in agriculture. It is not surprising that metabolicengineering applications inplant biotechnology in recent years have had incredibleachievements in agriculture, industry, and medicine.This...