... ( and A is calculated for methods II and III according to formula (20) As a matter of fact, methods I, II III can be compared only when using the same amount of information, v.i.z the same n and ... D )a; , Notice that k can be interpreted as in selection index theory as the ratio ofa within sire toa sire variance, since p(l - p)/(p2(.) is the asymptotic variance ofthe normit transformation ... in asymptotic theory (see for instance, formula 6a. 23, page 386 in Rao, 1973) and knowing that: is also one has, given Assuming toa i a as in section II B that, a priori, the f-Li’S i -L f with...
... which was within 10% (as shown fora point at 240 s) the equation H=[ (a+ Rt)/3]1/3, where a and R were used as the fitting parameters in order to obtain the growth rate R from the experimental data ... shown in Fig The good approximation tothe data for island heights larger than nm by a constant rate indicates that the late-stage growth rate was almost independent ofthe island height The early-stage ... decrease at the area around the island and, hence, the growth should cause the growth rate to decrease according tothe mechanism ofthe early stage of growth described above This corresponds to the...
... domain in an active conformation RLjunRP is an 40 kDa protein that forms an 80-kDa protein–DNA adduct To assess approximate molecular mass ofthe factors interacting withthe )148 to ) 124 region ... acrylamide) and analysed by autoradiography changes of · binding buffer over a period of 30 and autoradiographed Affinity purification ofthe factor(s) interacting withthe )148 to ) 124 region of ... Phosphatase-treated nuclear extracts were assayed for their DNA-binding capacity in standard EMSA UV crosslinking of DNA–protein adduct The EMSA reaction was carried out using ng labelled Jun)25 and...
... coordination, data interpretation, performed the statistical analysis, and drafted the manuscript AC participated inthe study design and coordination TL participated inthe analyses ofthe ovarian ... used for all the experiments All ofthe surgical procedures and the care given tothe animals were approved by the local committee for animal welfare The histopathological examination ofthe different ... compassionate patient treatment in which the DTA-H19 plasmid was intraperitoneally injected into the peritoneum ofa woman with advanced and recurrent ovarian carcinoma Following several infusions, a...
... bladder was determined by ImagePro Plus software Another healthy mice were used as control The total tumor area of each bladder was determined and the mean ofthe total areas was calculated for ... using the RNA STAT-60TM Total RNA/mRNA isolation reagent, according tothe manufacture’s instructions The RNA was treated by RNAse-free DNAse I to eliminate any contaminating DNA Total cDNA was ... activation was reported as a major mechanism forthe IGF2 overexpression ina variety of tumors including bladder carcinoma, hepatocellular carcinoma, breast cancer, ovarian cancer and prostate cancer...
... lives These data indicate a need for an improved approach to GERD management inthe primary care setting, tailoring treatment on an individual basis in order to lessen the impact ofthe disease ... (Germany) to 3.43 (Spain) forother acid-related gastrointestinal symptoms The mean overall impact score ranged from 3.30 (Germany) to 3.51 (Spain) Among extra-esophageal symptoms evaluated using ... interpretation and manuscript preparation Data analysis was provided by AstraZeneca All authors read and approved the final submission 13 14 Additional material 15 Additional file Extra-esophageal...
... pre-testing to check for errors or problems The data collectors were all fluent in Luo and English A final forward and back-translation was then produced and a final review conducted by the study team ... Boas MHA: Northern Uganda IDP Profiling Kampala: UNDP/ GoU/FAFO; 2005 Internally Displaced Camps in Lira and Pader, Northern Uganda A Baseline Health Survey Preliminary Report [http://www.msf .or. jp/news/baseline/Baseline.pdf] ... distribution of responses was acceptable forother response point for item one and fortheother items inthe SF-8 This suggests that the SF-8 was able to capture the range of health responses witha conflict-affected...
... Hawai‘i’s laws provide the Auditor with broad powers to examine all books, records, files, papers, and documents and all financial affairs of every agency The Auditor also has the authority to ... propose to mandate certain health insurance benefits Such bills cannot be enacted unless they are referred tothe Office ofthe Auditor for an assessment ofthe social and financial impact ofthe proposed ... cannot be demonstrated The tourism industry has begun to embrace performance management practices For example, inthe handbook Standard CVB Performance Reporting, the Destination Marketing Association...
... to manage program planning and marketing strategies for leisure tourism forthe North American market (United States and Canada) and corporate meetings and incentives domestically and internationally ... and the NFL The major contractors, the Hawai‘i Visitors and Convention Bureau (HVCB), Hawai‘i Tourism Japan (HTJ), SMG forthe marketing and operations ofthe Hawai‘i Convention Center, and the ... plan “intended to guide all stakeholders in working together to attain the state’s vision fora Hawai‘i that is the best place to live, work and visit.” Adopted in 2004, the Hawai‘i Tourism Strategic...
... that should serve as a roadmap forthe organization and its partners The HTA also plays a central role inthe management ofthe TSP, the state’s overall tourism road map, which identifies a shared ... measures in their plans for activities related to tourism promotions Tourism agencies in Montana, Florida, Texas, and Louisiana use a range of performance measures to establish baseline starting points, ... embrace performance management practices For example, inthe handbook Standard CVB Performance Reporting, the Destination Marketing Association International (DMAI) has developed best practice...
... provisions inthe HTJ contract that are not enforced by HTA, all relating to financial accountability, and a payment that appears to be based on an informal departure from the contractual compensation ... competent and independent scrutiny ofthe contractor’s accounting systems and related financial information Errors we found in financial reports relied on by HTA and a haphazard method for tracking an ... Authority Practices an Approach to Tourism Promotion That It Was Designed To Replace Informal deviations with Hawai‘i Tourism Japan impair financial accountability The contract with Hawai‘i Tourism...
... before and during an event include sending a delegation toa mainland conference in order to build attendance fora Hawai‘i event the following year In one case, SMG spent $8,000 to send Hawaiian ... ignored those documents as they pursued an annual budgetary approach to planning and spending Inother words, by choosing to map out their strategy and appropriate funds on a year -to- year basis, ... feasible With regard to its oversight over contractors, the Hawai‘i Tourism Authority should: aTothe extent possible, incorporate objectively measurable outcomes and performance indicators in its...
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... consideration and intention to travel to Hawaiʻi as the most controllable and measurable performance metrics” and contracted witha leading international research company to track the impact and ... opinions and subjective evaluations for an accounting of taxpayer funds Finally, the use of performance measures is not limited to broad, agencylevel activities Measures are useful for planning for and ... brand marketer as suggested inthe response The authority has a dual role as lead agency forthe development ofthe state-wide Hawai‘i Tourism Strategic Plan and that of an active partner in...
... numeric rating scale ranging from (indicating no pain) to 10 (indicating pain as bad as you can imagine) Higher scores indicate greater pain severity Based on previous analyses, scores oftoare considered ... important forthe evaluation of FM treatments and priority setting in health care, for example by providing input data forthe evaluation of medical resource utilization, costs and quality of ... trials for FM therapies and aspects of domains and outcome measures that should be part ofa concerted research agenda for FM researchers [12] The identified domains included pain, patient global...
... lymphoma incidence in Wales witha ratio of 1:4 [1] Table 1: Anatomical location of lymphomatous lymph nodes (n = 62) Anatomical location Number of cases Cervical Inguinal Axillary Intra-abdominal ... lymphomas, in particular HL, was stimulated by a report from Stanford University inthe late 1960s which showed that the performance ofa staging laparotomy altered the stage of disease in 42% of cases, ... half ofthe cases although this was performed in 81% of head and neck lymphadenopathy in accordance with practice guidelines [4] The importance of performing an FNAC in patients with cervical...
... Acetylcholine and excitatory amino acids J Neurotrauma 1992, 9:S173-S187 Katayama Y, Becker DP, Tamura T, Hovda DA: Massive increases in extracellular potassium and the indiscriminate release of glutamate ... activated by increases in [Ca2+]i and is also known to phosphorylate GABAAR [22] Kao et al [21] suggested that injuryinduced increases in glutamate activated NMDA receptors, increasing [Ca2+]i and subsequently ... similarities of action that alter excitatory/inhibitory balance, rather than a direct effect on the GABAAR Both diltiazem and DZ inhibit Ca2+ release induced by sodium presence in rat brain mitochondria...
... Written informed consent was obtained from the patient for publication of this case report and accompanying images A copy ofthe written consent is available for review by the Editor -in- Chief of this ... ultrasonography when postoperative impingement is suspected because of inflammatory changes inthe subacromial space because of surgery The introduction of rotator cuff MITEK anchors brought forth ... subacromial space and was inconclusive The intra-operative photographs ofthe repair did not show any abnormality or evidence of impingement syndrome (Figure 1) The patient was taken back to theatre for...
... Written informed consent was obtained from the patients for publication of these case reports and any accompanying images A copy ofthe written consent is available for review by the Editor -in- Chief ... urethral stricture was found Biodegradable grafts seem to be an ideal solution forthe repair ofthe urethra as well as other segments ofthe urinary tract SIS acts like a framework forthe host-tissue ... described, and various types of autologous materials have been used in order to bridge urethral defects [1] In some cases, the search for new applicable materials became mandatory because ofthe morbidity...
... at SEPs once information about the availability of citrate became ubiquitous among drug injectors Finally, this study demonstrates the value of utilising routinely collected monitoring data to ... £20 of heroin normally prepared and because packaging a smaller amount would be unfeasible Injectors liked the idea of single use sachets which were also deemed to decrease the risk of contamination ... affect attendance either, indicating that citrate can be added tothe spectrum of interventions offered by SEPs without any apparent negative consequences Furthermore, injectors who already attended...